Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection

Circulation

Volumn 124, Issue 25, 2011, Pages 2892-2902

  Horstkotte, Jan ^a   Perisic, Tamara ^c,d   Schneider, Manuela ^a   Lange, Philipp ^a   Schroeder, Melanie ^a   Kiermayer, Claudia ^e,j   Hinkel, Rabea ^a   Ziegler, Tilman ^a   Mandal, Pankaj K ^c,d   David, Robert ^a   Schulz, Sabine ^f   Schmitt, Sabine ^f   Widder, Julian ^e,g   Sinowatz, Fred ^b   Becker, Bernhard F ^a   Bauersachs, Johann ^e,g   Naebauer, Michael ^a   Franz, Wolfgang M ^a,e,j   Jeremias, Irmela ^b   Brielmeier, Markus ^b,e   Zischka, Hans ^f   Conrad, Marcus ^c,h,i   Kupatt, Christian ^a,b,e   more..

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b Department of Veterinary Anatomy II ^*  (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e INSTITUTE OF EPIDEMIOLOGY   (Germany)

^f Institute of Toxicology   (Germany)

^g Klinik für Kardiologie und Angiologie   (Germany)

^h HANNOVER MEDICAL SCHOOL   (Germany)

ⁱ GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^j Munich Heart Alliance   (Germany)

more..

Author keywords

Infarct size; Ischemia reperfusion injury; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CYCLOSPORIN A; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOCHONDRIAL THIOREDOXIN REDUCTASE; REACTIVE OXYGEN METABOLITE; TAMOXIFEN; THIOREDOXIN REDUCTASE; THIOREDOXIN REDUCTASE 1; THIOREDOXIN REDUCTASE 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; CELL DEATH; EMBRYONIC STEM CELL; ENDOTHELIUM CELL; ENZYME ACTIVITY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HYPOXIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REOXYGENATION; REPERFUSION INJURY; REVIEW; SYSTOLIC DYSFUNCTION;

ACETYLCYSTEINE; ANIMALS; CELL DEATH; CELLS, CULTURED; CYCLOSPORINE; EMBRYONIC STEM CELLS; ENDOTHELIAL CELLS; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEMATOPOIETIC STEM CELLS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; OXIDATIVE STRESS; SULFHYDRYL COMPOUNDS; THIOREDOXIN REDUCTASE 1; THIOREDOXIN REDUCTASE 2;

EID: 84155162827     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.111.059253     Document Type: Review

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