Synthesis, absolute configuration, and bacterial mutagenicity of the 8 stereoisomeric vicinal diol epoxides at the terminal benzo ring of carcinogenic dibenz[ a,h ]anthracene

Chemical Research in Toxicology

Volumn 24, Issue 12, 2011, Pages 2258-2268

  Frank, Heinz ^a,b   Funk, Mario ^a,c   Oesch, Franz ^a   Platt, Karl L ^a,b  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b Prof Dr Gernot Grimmer Foundation   (Germany)

^c EVONIK INDUSTRIES AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 CHLOROPERBENZOIC ACID; 3,4 BIS(BENZOYLOXY) 3,4 DIHYDRODIBENZ[A,H]ANTHRACENE; 3,4 DIHYDROXY 1,2 EPOXY 1,2,3,4 TETRAHYDRODIBENZ[A,H] ANTHRACENE; 3,4 DIHYDROXY 3,4 DIHYDRODIBENZ[A,H]ANTHRACENE; ANION; C 3,T 4 DIHYDROXY R 1,2 EPOXY 1,2,3,4 TETRAHYDRODIBENZ[A,H] ANTHRACENE; DIBENZ[A,H]ANTHRACENE; DIHYDROXYBENZO[A]PYRENE OXIDE; HISTIDINE; MUTAGENIC AGENT; T 2 BROMO R 1,T 3,C 4 TRIHYDROXY 1,2,3,4 TETRAHYDRODIBENZ[A,H] ANTHRACENE; T 3,C 4 DIHYDROXY R 1,2 EPOXY 1,2,3,4 TETRAHYDRODIBENZ[A,H] ANTHRACENE; UNCLASSIFIED DRUG;

ANION EXCHANGE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; DRUG CONFORMATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MUTAGENICITY; OXIDATION; SALMONELLA TYPHIMURIUM; STEREOCHEMISTRY; SYNTHESIS;

BENZ(A)ANTHRACENES; CARCINOGENS; EPOXY COMPOUNDS; MOLECULAR CONFORMATION; MUTAGENICITY TESTS; OXIDATION-REDUCTION; SALMONELLA TYPHIMURIUM; STEREOISOMERISM;

EID: 84055223003     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx200398b     Document Type: Article

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