Liquid-chromatographic profiling of Saponinum album (Merck)

Pharmazie

Volumn 66, Issue 10, 2011, Pages 744-746

  Weng, Alexander ^a   Thakur, M ^a   Schindler, A ^b   Fuchs, H ^a   Melzig, M F ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SAPONIN DERIVATIVE; SAPONINUM ALBUM; SAPORIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ELECTROSPRAY MASS SPECTROMETRY; ELECTROSPRAY TIME OF FLIGHT MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MEDICINAL PLANT; NONHUMAN; PLANT SEED; SAPONARIA OFFICINALIS;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARBOHYDRATE SEQUENCE; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MOLECULAR SEQUENCE DATA; SAPONARIA; SAPONINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRITERPENES;

EID: 84055200296     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2011.1575     Document Type: Article

References (7)

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2. Barbieri L, Valbonesi P, Gorini P, Pession A, Stirpe F (1996) Polynucleotide: adenosine glycosidase activity of saporin-L1: effect on DNA, RNA and poly(A). Biochem J 319 (Pt 2): 507-513.
3. Francis G, Kerem Z, Makkar HP, Becker K (2002) The biological action of saponins in animal systems: a review. Br J Nutr 88: 587-605. (Pubitemid 36082888)
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5. Weng A, Bachran C, Fuchs H, Melzig MF (2008) Soapwort saponins trigger clathrin-mediated endocytosis of saporin, a type I ribosome-inactivating protein. Chem Biol Interact 176: 204-211.
6. Weng A, Bachran D, Gorick C, Bachran C, Fuchs H, Melzig MF (2009) A simple method for isolation of Gypsophila saponins for the combined application of targeted toxins and saponins in tumor therapy. Planta Med 75: 1421-1422.
7. Weng A, Jenett-Siems K, Schmieder P, Bachran D, Bachran C, Gorick C, Thakur M, Fuchs H, Melzig MF (2010) A convenient method for saponin isolation in tumour therapy. J Chromatogr B Analyt Technol Biomed Life Sci 878: 713-718.