Polyvinylpyrrolidone storage disease presenting as pathologic fracture and anemia: Report of a case with imprint cytology

Diagnostic Cytopathology

Volumn 40, Issue 1, 2012, Pages 69-72

  Huang, Wen Chih ^a   Chang, Chih Hung ^a   Tsai, Chien Chen ^a  

^a FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

Author keywords

imprint cytology; pathologic fracture; polyvinylpyrrolidone storage disease

Indexed keywords

BLOOD SUBSTITUTE; CD68 ANTIGEN; CONGO RED; POVIDONE;

AGED; ANEMIA; ARTICLE; AVASCULAR NECROSIS; BLOOD ANALYSIS; BONE BIOPSY; BONE LESION; BONE METASTASIS; BONE SCINTISCANNING; BONE TUMOR; CASE REPORT; CHORDOMA; CYTOLOGY; DIFFERENTIAL DIAGNOSIS; FEMALE; FEMUR FRACTURE; GENETIC DISORDER; HIP PAIN; HIP RADIOGRAPHY; HUMAN; HYPERTENSION; IMMUNOHISTOCHEMISTRY; IMPRINT CYTOLOGY; LIPOSARCOMA; NEUROGENIC BLADDER; NUTRITIONAL SUPPORT; OPEN REDUCTION; OSTEOPOROSIS; OSTEOSYNTHESIS; PATHOLOGIC FRACTURE; POLYVINYLPYRROLIDONE STORAGE DISEASE; PRIORITY JOURNAL; SPINAL CORD ATROPHY; STORAGE DISEASE;

AGED; ANEMIA; BONE NEOPLASMS; DIAGNOSIS, DIFFERENTIAL; FEMALE; FEMORAL FRACTURES; HUMANS; HYPERTENSION; INCLUSION BODIES; INTERVERTEBRAL DISC DEGENERATION; METABOLIC DISEASES; OSTEONECROSIS; OSTEOPOROSIS; PLASMA SUBSTITUTES; POVIDONE; URINARY BLADDER, NEUROGENIC;

EID: 84055189767     PISSN: 87551039     EISSN: 10970339     Source Type: Journal    
DOI: 10.1002/dc.21607     Document Type: Article

References (15)

1. Ravin HA, Seligman AM, Fine J,. Polyvinylpyrrolidone as a plasma expander. Studies on its excretion, distribution and metabolism. N Engl J Med 1952; 247: 921-929.
2. Reske-Nielsen E, Bojsen-Moller M, Vetner M, Hansen JC,. Polyvinylpyrrolidone-storage disease. Light microscopical, ultrastructural and chemical verification. Acta Pathol Microbiol Scand 1976; 84: 397-405.
3. Kuo TT, Hu S, Huang CL, et al. Cutaneous involvement in polyvinylpyrrolidone storage disease: A clinicopathologic study of five patients, including two patients with severe anemia. Am J Surg Pathol 1997; 21: 1361-1367. (Pubitemid 27460863)
4. Kuo TT, Hsueh S,. Mucicarminophilic histiocytosis. A polyvinyl- pyrrolidone (PVP) storage disease simulating signet-ring cell carcinoma. Am J Surg Pathol 1984; 8: 419-428. (Pubitemid 14112134)
5. Dunn P, Kuo TT, Shih LY, Wang PN, Sun CF, Chang MJ,. Bone marrow failure and myelofibrosis in a case of PVP storage disease. Am J Hematol 1998; 57: 68-71. (Pubitemid 28047202)
6. Kepes JJ, Chen WY, Jim YF,. "Mucoid dissolution" of bones and multiple pathologic fractures in a patient with past history of intravenous administration of polyvinylpyrrolidone (PVP). A case report. Bone Miner 1993; 22: 33-41. (Pubitemid 23272788)
7. Hewan-Lowe K, Hamners Y, Lyons JM, Wilcox CM,. Polyvinylpyrrolidone storage disease: A source of error in the diagnosis of signet-ring cell gastric adenocarcinoma. Ultrastruct Pathol 1994; 18: 271-278. (Pubitemid 24131638)
8. Burks RI,. Povidone-iodine solution in wound treatment. Phys Ther 1998; 78: 212-218. (Pubitemid 28106239)
9. Bühler V,. Polyvinylpyrrolidone excipients for pharmaceuticals. New York: Springer; 2005. 1-254 p.
10. Lachapelle JM, Tennstedt D,. Polyvinylpyrrolidone (povidone) storage in RX-damaged skin following procaine-povidone intramuscular injections. Dermatologica 1982; 165: 573-579. (Pubitemid 13141906)
11. Dupont A, Lachapelle JM,. Dermatitis due to a medicamentous deposit during the treatment of diabetes insipidus. Bull Soc Fr Dermatol Syphiligr 1964; 71: 508-509.
12. Thivolet J, Leung TK, Duverne J, Leung J, Volle H,. Ultrastructural morphology and histochemistry (acid phosphatase) of the cutaneous infiltration by polyvinylpyrrolidone. Br J Dermatol 1970; 83: 661-669.
13. Chi CC, Wang SH, Kuo TT,. Localized cutaneous polyvinylpyrrolidone storage disease mimicking cheilitis granulomatosa. J Cutan Pathol 2006; 33: 454-457.
14. Adachi A, Fukunaga A, Hayashi K, Kunisada M, Horikawa T,. Anaphylaxis to polyvinylpyrrolidone after vaginal application of povidone-iodine. Contact Dermatitis 2003; 48: 133-136. (Pubitemid 36683479)
15. Rönnau AC, Wulferink M, Gleichmann E, et al. Anaphylaxis to polyvinylpyrrolidone in an analgesic preparation. Br J Dermatol 2000; 143: 1055-1058.