A dose-volume analysis of radiation pneumonitis in non-small cell lung cancer patients treated with stereotactic body radiation therapy

International Journal of Radiation Oncology Biology Physics

Volumn 82, Issue 1, 2012, Pages 457-462

  Barriger, R Bryan ^a   Forquer, Jeffrey A ^b,c   Brabham, Jeffrey G ^d   Andolino, David L ^a   Shapiro, Ronald H ^a   Henderson, Mark A ^a   Johnstone, Peter A S ^a   Fakiris, Achilles J ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Toledo Radiation Oncology Inc   (United States)

^c MEDICAL COLLEGE OF OHIO   (United States)

^d FLORIDA HOSPITAL CANCER INSTITUTE   (United States)

Author keywords

Lung cancer; Pneumonitis; Radiotherapy; SBRT; Toxicity

Indexed keywords

AFTER-TREATMENT; CHEST RADIATION; DATA POINTS; DOSE-VOLUME ANALYSIS; DOSE-VOLUME HISTOGRAMS; LUNG CANCER; MEAN LUNG DOSE; NODE-NEGATIVE; NON SMALL CELL LUNG CANCER; OVERALL RATE; PNEUMONITIS; RADIATION DOSE; RADIATION PNEUMONITIS; RISK FACTORS; SBRT; STEREOTACTIC BODY RADIATION THERAPY; STEREOTACTIC BODY RADIOTHERAPY;

BIOLOGICAL ORGANS; DISEASES; DOSIMETRY; PATIENT MONITORING; RADIATION; TOXICITY;

RADIOTHERAPY;

ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; DISEASE SEVERITY; DOSIMETRY; FEMALE; FOLLOW UP; HUMAN; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIATION PNEUMONIA; RISK ASSESSMENT; STEREOTACTIC BODY RADIATION THERAPY; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; DOSE FRACTIONATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM GRADING; RADIATION PNEUMONITIS; RADIOSURGERY; RISK FACTORS; STATISTICS, NONPARAMETRIC; TUMOR BURDEN;

EID: 83955164332     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.08.056     Document Type: Article

References (27)

1. R. Timmerman, R. Paulus, and J. Galvin Stereotactic body radiation therapy for inoperable early stage lung cancer JAMA 303 2010 1070 1076
2. H. Onishi, T. Araki, and H. Shirato Stereotactic hypofractionated high-dose irradiation for Stage I nonsmall cell lung carcinoma: Clinical outcomes in 245 subjects in a Japanese multiinstitutional study Cancer 101 2004 1623 1631
3. Y. Nagata, K. Takayama, and Y. Matsuo Clinical outcomes of a Phase I/II study of 48 Gy of stereotactic body radiotherapy in 4 fractions for primary lung cancer using a stereotactic body frame Int J Radiat Oncol Biol Phys 63 2005 1427 1431
4. R.C. McGarry, L. Papiez, and M. Williams Stereotactic body radiation therapy of early-stage non-small-cell lung carcinoma: Phase I study Int J Radiat Oncol Biol Phys 63 2005 1010 1015
5. A.J. Fakiris, R.C. McGarry, and C.T. Yiannoutsos Stereotactic body radiation therapy for early-stage non-small-cell lung carcinoma: Four-year results of a prospective Phase II study Int J Radiat Oncol Biol Phys 75 2009 677 682
6. U. Ricardi, A.R. Filippi, and A. Guarneri Stereotactic body radiation therapy for early stage non-small cell lung cancer: Results of a prospective trial Lung Cancer 68 2010 72 77
7. M. Uematsu, A. Shioda, and A. Suda Computed tomography-guided frameless stereotactic radiotherapy for Stage I non-small cell lung cancer: A 5-year experience Int J Radiat Oncol Biol Phys 51 2001 666 670
8. N.C. van der Voort van Zyp, J.B. Prevost, and M.S. Hoogeman Stereotactic radiotherapy with real-time tumor tracking for non-small cell lung cancer: Clinical outcome Radiother Oncol 91 2009 296 300
9. K.L. Stephans, T. Djemil, and C.A. Reddy A comparison of two stereotactic body radiation fractionation schedules for medically inoperable Stage I non-small cell lung cancer: The Cleveland Clinic experience J Thorac Oncol 4 2009 976 982
10. Grills IS, Mangona VS, Welsh R, et al. Outcomes after stereotactic lung radiotherapy or wedge resection for Stage I non-small-cell lung cancer. J Clin Oncol xxx;28:928-935.
11. G.M. Videtic, K. Stephans, and C. Reddy Intensity-modulated radiotherapy-based stereotactic body radiotherapy for medically inoperable early-stage lung cancer: Excellent local control Int J Radiat Oncol Biol Phys 77 2010 344 349
12. R.C. McGarry, G. Song, and P. des Rosiers Observation-only management of early stage, medically inoperable lung cancer: Poor outcome Chest 121 2002 1155 1158
13. R. Timmerman, L. Papiez, and R. McGarry Extracranial stereotactic radioablation: Results of a Phase I study in medically inoperable Stage I non-small cell lung cancer Chest 124 2003 1946 1955
14. M. Henderson, R. McGarry, and C. Yiannoutsos Baseline pulmonary function as a predictor for survival and decline in pulmonary function over time in patients undergoing sterotactic body radiotherapy for the treatment of Stage I non-small-cell lung cancer Int J Radiat Oncol Biol Phys 72 2008 404 409
15. R. Timmerman, R. McGarry, and C. Yiannoutsos Excessive toxicity when treating central tumors in a Phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer J Clin Oncol 24 2006 4833 4839
16. J.A. Forquer, A.J. Fakiris, and R.D. Timmerman Brachial plexopathy from stereotactic body radiotherapy in early-stage NSCLC: Dose-limiting toxicity in apical tumor sites Radiother Oncol 93 2009 408 413
17. D.L. Andolino, J.A. Forquer, and M.A. Henderson Maximum dose to chest wall greater than 60 Gy and volume of chest wall receiving greater than 30 Gy predict risk of chest wall toxicity following stereotactic body radiation therapy (SBRT) Int J Radiat Oncol Biol Phys 75 suppl. 2009 S60
18. J.D. Bradley, A. Hope, and I. El Naqa A nomogram to predict radiation pneumonitis, derived from a combined analysis of RTOG 9311 and institutional data Int J Radiat Oncol Biol Phys 69 2007 985 992
19. A.J. Hope, P.E. Lindsay, and I. El Naqa Modeling radiation pneumonitis risk with clinical, dosimetric, and spatial parameters Int J Radiat Oncol Biol Phys 65 2006 112 124
20. M.V. Graham, J.A. Purdy, and B. Emami Clinical dose-volume histogram analysis for pneumonitis after 3D treatment for non-small cell lung cancer (NSCLC) Int J Radiat Oncol Biol Phys 45 1999 323 329
21. Barriger RB, Fakiris AJ, Hanna N, et al. Dose-volume analysis of radiation pneumonitis in non-small-cell lung cancer patients treated with concurrent cisplatinum and etoposide with or without consolidation docetaxel. Int J Radiat Oncol Biol Phys. In press.
22. F.L. Greene, D.L. Page, and I.D. Fleming AJCC cancer staging handbook from the AJCC cancer staging manual 6th ed. 2002 Springer-Verlag New York
23. K.E. Rusthoven, B.D. Kavanagh, and S.H. Burri Multi-institutional Phase I/II trial of stereotactic body radiation therapy for lung metastases J Clin Oncol 27 2009 1579 1584
24. N.E. Dunlap, J. Cai, and G.B. Biedermann Chest wall volume receiving >30 Gy predicts risk of severe pain and/or rib fracture after lung stereotactic body radiotherapy Int J Radiat Oncol Biol Phys 76 2010 796 801
25. B.S. Hoppe, B. Laser, and A.V. Kowalski Acute skin toxicity following stereotactic body radiation therapy for Stage I non-small-cell lung cancer: Who's at risk? Int J Radiat Oncol Biol Phys 72 2008 1283 1286
26. A. Linda, M. Trovo, and J.D. Bradley Radiation injury of the lung after stereotactic body radiation therapy (SBRT) for lung cancer: A timeline and pattern of CT changes Eur J Radiol 79 2011 147 154
27. Z. Kocak, E.S. Evans, and S.M. Zhou Challenges in defining radiation pneumonitis in patients with lung cancer Int J Radiat Oncol Biol Phys 62 2005 635 638