A general assessment of the physiochemical factors that influence leachables accumulation in pharmaceutical drug products and related solutions

PDA Journal of Pharmaceutical Science and Technology

Volumn 65, Issue 2, 2011, Pages 166-176

  Jenke, Dennis ^a  

^a BAXTER HEALTHCARE CORPORATION   (United States)

Author keywords

Extractables; Leachables; Material drug product interactions; Suitability for use

Indexed keywords

BENZOIC ACID DERIVATIVE; BENZYL ALCOHOL; DRUG; FATTY ACID; HEXANE; LEACHABLE; OCTANOL; ORGANIC COMPOUND; PHTHALIC ACID DIETHYL ESTER; PLASTIC; POLYOLEFIN; UNCLASSIFIED DRUG; SOLUTION AND SOLUBILITY;

AQUEOUS SOLUTION; CONCENTRATION (PARAMETERS); CONTAINER; DEGRADATION; DIFFUSION; DRUG CONTAMINATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG INCOMPATIBILITY; DRUG MANUFACTURE; DRUG PACKAGING; DRUG SOLUTION; EXTRACTION; IONIC STRENGTH; KINETICS; LEACHABLE ACCUMULATION; MATERIAL COATING; MOLECULAR WEIGHT; PH; PHASE PARTITIONING; PHYSICAL CHEMISTRY; POLARIZATION; REVIEW; TEMPERATURE; THERMODYNAMICS; VOLUMETRY; CHEMISTRY; SOLUTION AND SOLUBILITY;

DRUG CONTAMINATION; DRUG PACKAGING; ORGANIC CHEMICALS; PHARMACEUTICAL PREPARATIONS; PHARMACEUTICAL SOLUTIONS; PLASTICS; SOLUTIONS;

EID: 83755207346     PISSN: 10797440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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