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Volumn 66, Issue 1, 2012, Pages 21-27

Adoptive immunotherapy for postoperative hepatocellular carcinoma: A systematic review

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIBODY; DOXORUBICIN; INTERLEUKIN 2;

EID: 83755174655     PISSN: 13685031     EISSN: 17421241     Source Type: Journal    
DOI: 10.1111/j.1742-1241.2011.02814.x     Document Type: Review
Times cited : (37)

References (53)
  • 1
    • 7044231396 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Recent trends in the United States
    • DOI 10.1053/j.gastro.2004.09.013, PII S0016508504015926
    • El-Serag HB,. Hepatocellular carcinoma: recent trends in the United States. Gastroenterology 2004; 127 (5 Suppl 1): S27-34. (Pubitemid 39423367)
    • (2004) Gastroenterology , vol.127 , Issue.SUPPL.
    • El-Serag, H.B.1
  • 2
    • 47249128185 scopus 로고    scopus 로고
    • Trends in mortality from hepatocellular carcinoma in Europe, 1980-2004
    • DOI 10.1002/hep.22312
    • Bosetti C, Levi F, Boffetta P, et al., Trends in mortality from hepatocellular carcinoma in Europe, 1980-2004. Hepatology 2008; 48: 137-45. (Pubitemid 351980469)
    • (2008) Hepatology , vol.48 , Issue.1 , pp. 137-145
    • Bosetti, C.1    Levi, F.2    Boffetta, P.3    Lucchini, F.4    Negri, E.5    La Vecchia, C.6
  • 3
    • 33847369349 scopus 로고    scopus 로고
    • Hepatocellular Cancer: A Guide for the Internist
    • DOI 10.1016/j.amjmed.2006.11.020, PII S0002934306014008
    • Parikh S, Hyman D,. Hepatocellular cancer: a guide for the internist. Am J Med 2007; 120: 194-202. (Pubitemid 46341174)
    • (2007) American Journal of Medicine , vol.120 , Issue.3 , pp. 194-202
    • Parikh, S.1    Hyman, D.2
  • 5
    • 77953055678 scopus 로고    scopus 로고
    • Endoscopic ultrasound and fine-needle aspiration for the diagnosis of hepatocellular carcinoma
    • Maheshwari A, Kantsevoy S, Jagannath S, et al., Endoscopic ultrasound and fine-needle aspiration for the diagnosis of hepatocellular carcinoma. Clin Liver Dis 2010; 14: 325-32.
    • (2010) Clin Liver Dis , vol.14 , pp. 325-332
    • Maheshwari, A.1    Kantsevoy, S.2    Jagannath, S.3
  • 6
    • 78751590945 scopus 로고    scopus 로고
    • Pre-operative liver biopsy in cirrhotic patients with early hepatocellular carcinoma represents a safe and accurate diagnostic tool for tumour grading assessment
    • Colecchia A, Scaioli E, Montrone L, et al., Pre-operative liver biopsy in cirrhotic patients with early hepatocellular carcinoma represents a safe and accurate diagnostic tool for tumour grading assessment. J Hepatol 2011; 54: 300-5.
    • (2011) J Hepatol , vol.54 , pp. 300-305
    • Colecchia, A.1    Scaioli, E.2    Montrone, L.3
  • 7
    • 78649854047 scopus 로고    scopus 로고
    • Administration of interferon for two or more years decreases early stage hepatocellular carcinoma recurrence rate after radical ablation: A retrospective study of hepatitis C virus-related liver cancer
    • Ikeda K, Kobayashi M, Seko Y, et al., Administration of interferon for two or more years decreases early stage hepatocellular carcinoma recurrence rate after radical ablation: a retrospective study of hepatitis C virus-related liver cancer. Hepatol Res 2010; 40: 1168-75.
    • (2010) Hepatol Res , vol.40 , pp. 1168-1175
    • Ikeda, K.1    Kobayashi, M.2    Seko, Y.3
  • 8
    • 77955623464 scopus 로고    scopus 로고
    • Relationship between serum heparanase and microscopic venous invasion in patients with hepatocellular carcinoma
    • Wang GB, Zhou XY, Wang XQ,. Relationship between serum heparanase and microscopic venous invasion in patients with hepatocellular carcinoma. Am J Clin Pathol 2010; 134: 242-8.
    • (2010) Am J Clin Pathol , vol.134 , pp. 242-248
    • Wang, G.B.1    Zhou, X.Y.2    Wang, X.Q.3
  • 9
    • 77957370997 scopus 로고    scopus 로고
    • Predictors of microvascular invasion before hepatectomy for hepatocellular carcinoma
    • Kaibori M, Ishizaki M, Matsui K, et al., Predictors of microvascular invasion before hepatectomy for hepatocellular carcinoma. J Surg Oncol 2010; 102: 462-8.
    • (2010) J Surg Oncol , vol.102 , pp. 462-468
    • Kaibori, M.1    Ishizaki, M.2    Matsui, K.3
  • 10
    • 0031051106 scopus 로고    scopus 로고
    • Hematogenous spreading of hepatocellular carcinoma cells: Possible participation in recurrence in the liver
    • DOI 10.1002/hep.510250312
    • Funaki NO, Tanaka J, Seto SI, et al., Hematogenous spreading of hepatocellular carcinoma cells: possible participation in recurrence in the liver. Hepatology 1997; 25: 564-8. (Pubitemid 27106434)
    • (1997) Hepatology , vol.25 , Issue.3 , pp. 564-568
    • Funaki, N.O.1    Tanaka, J.2    Seto, S.-I.3    Kasamatsu, T.4    Kaido, T.5    Imamura, M.6
  • 11
    • 21644482195 scopus 로고    scopus 로고
    • The continuing challenge of hepatic cancer in Asia
    • Lai EC, Lau WY,. The continuing challenge of hepatic cancer in Asia. Surgeon 2005; 3: 210-5. (Pubitemid 40932721)
    • (2005) Surgeon , vol.3 , Issue.3 , pp. 210-215
    • Lai, E.C.H.1    Lau, W.Y.2
  • 12
    • 0141491273 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • DOI 10.1016/S0140-6736(03)14964-1
    • Llovet JM, Burroughs A, Bruix J,. Hepatocellular carcinoma. Lancet 2003; 362: 1907-17. (Pubitemid 37518510)
    • (2003) Lancet , vol.362 , Issue.9399 , pp. 1907-1917
    • Llovet, J.M.1    Burroughs, A.2    Bruix, J.3
  • 13
    • 77957242266 scopus 로고    scopus 로고
    • Postoperative adjuvant transarterial chemoembolization for participants with hepatocellular carcinoma: A meta-analysis
    • Zhong JH, Li LQ,. Postoperative adjuvant transarterial chemoembolization for participants with hepatocellular carcinoma: a meta-analysis. Hepatol Res 2010; 40: 943-53.
    • (2010) Hepatol Res , vol.40 , pp. 943-953
    • Zhong, J.H.1    Li, L.Q.2
  • 14
    • 77953125020 scopus 로고    scopus 로고
    • Is there a role for adjuvant treatment after hepatic resection for hepatocellular carcinoma?
    • Tan A, Aucejo F, Kim R,. Is there a role for adjuvant treatment after hepatic resection for hepatocellular carcinoma? Oncology 2010; 78: 161-71.
    • (2010) Oncology , vol.78 , pp. 161-171
    • Tan, A.1    Aucejo, F.2    Kim, R.3
  • 15
    • 77954373047 scopus 로고    scopus 로고
    • Dendritic cells fused with allogeneic hepatocellular carcinoma cell line compared with fused autologous tumor cells as hepatocellular carcinoma vaccines
    • Yang JY, Cao DY, Ma LY, et al., Dendritic cells fused with allogeneic hepatocellular carcinoma cell line compared with fused autologous tumor cells as hepatocellular carcinoma vaccines. Hepatol Res 2010; 40: 505-13.
    • (2010) Hepatol Res , vol.40 , pp. 505-513
    • Yang, J.Y.1    Cao, D.Y.2    Ma, L.Y.3
  • 16
    • 33748515904 scopus 로고    scopus 로고
    • Is there a role for immunotherapy in hepatocellular carcinoma?
    • DOI 10.1016/j.dld.2005.12.004, PII S1590865805005256
    • Zerbini A, Pilli M, Ferrari C, et al., Is there a role for immunotherapy in hepatocellular carcinoma? Dig Liver Dis 2006; 38: 221-5. (Pubitemid 44356180)
    • (2006) Digestive and Liver Disease , vol.38 , Issue.4 , pp. 221-225
    • Zerbini, A.1    Pilli, M.2    Ferrari, C.3    Missale, G.4
  • 17
    • 7044226216 scopus 로고    scopus 로고
    • Immunotherapeutic strategies for hepatocellular carcinoma
    • DOI 10.1053/j.gastro.2004.09.038, PII S0016508504016178
    • Butterfield LH,. Immunotherapeutic strategies for hepatocellular carcinoma. Gastroenterology 2004; 127 (Suppl 51): S232-41. (Pubitemid 39423392)
    • (2004) Gastroenterology , vol.127 , Issue.SUPPL.
    • Butterfield, L.H.1
  • 18
    • 0033610734 scopus 로고    scopus 로고
    • Improving the quality of reports of meta-analyses of randomised controlled trials: The QUOROM statement. Quality of Reporting of Meta-analyses
    • Moher D, Cook DJ, Eastwood S, et al., Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of Reporting of Meta-analyses. Lancet 1999; 354: 1896-900.
    • (1999) Lancet , vol.354 , pp. 1896-1900
    • Moher, D.1    Cook, D.J.2    Eastwood, S.3
  • 19
    • 0034596475 scopus 로고    scopus 로고
    • Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: A randomised trial
    • Takayama T, Sekine T, Makuuchi M, et al., Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet 2000; 356: 802-7.
    • (2000) Lancet , vol.356 , pp. 802-807
    • Takayama, T.1    Sekine, T.2    Makuuchi, M.3
  • 20
    • 57449105089 scopus 로고    scopus 로고
    • A randomized, controlled trial of postoperative adjuvant cytokine-induced killer cells immunotherapy after radical resection of hepatocellular carcinoma
    • Dong H, LI Q, Wang J, et al., A randomized, controlled trial of postoperative adjuvant cytokine-induced killer cells immunotherapy after radical resection of hepatocellular carcinoma. Dig Liver Dis 2009; 41: 36-41.
    • (2009) Dig Liver Dis , vol.41 , pp. 36-41
    • Dong, H.1    Li, Q.2    Wang, J.3
  • 21
    • 40749152776 scopus 로고    scopus 로고
    • Minimally invasive treatment combined with cytokine-induced killer cells therapy lower the short-term recurrence rates of hepatocellular carcinomas
    • DOI 10.1097/CJI.0b013e31815a121b, PII 0000237120080100000008
    • Weng DS, Zhou J, Zhou QM, et al., Minimally invasive treatment combined with cytokine-induced killer cells therapy lower the short-term recurrence rates of hepatocellular carcinomas. J Immunother 2008; 31: 63-71. (Pubitemid 351619405)
    • (2008) Journal of Immunotherapy , vol.31 , Issue.1 , pp. 63-71
    • Weng, D.-S.1    Zhou, J.2    Zhou, Q.-M.3    Zhao, M.4    Wang, Q.-J.5    Huang, L.-X.6    Li, Y.-Q.7    Chen, S.-P.8    Wu, P.-H.9    Xia, J.-C.10
  • 22
    • 0029180882 scopus 로고
    • The effects of combined hepatectomy and immuno-chemotherapy on postoperative recurrence rate of primary liver cancer
    • Zhou WP, Wu MC, Chen H,. [The effects of combined hepatectomy and immuno-chemotherapy on postoperative recurrence rate of primary liver cancer]. Zhonghua Wai Ke Za Zhi 1995; 33: 35-7.
    • (1995) Zhonghua Wai Ke Za Zhi , vol.33 , pp. 35-37
    • Zhou, W.P.1    Wu, M.C.2    Chen, H.3
  • 23
    • 0028997445 scopus 로고
    • Adjuvant chemoimmunotherapy for hepatocellular carcinoma patients. Adriamycin, interleukin-2, and lymphokine-activated killer cells versus adriamycin alone
    • Kawata A, Une Y, Hosokawa M, et al., Adjuvant chemoimmunotherapy for hepatocellular carcinoma patients. Adriamycin, interleukin-2, and lymphokine-activated killer cells versus adriamycin alone. Am J Clin Oncol 1995; 18: 257-62.
    • (1995) Am J Clin Oncol , vol.18 , pp. 257-262
    • Kawata, A.1    Une, Y.2    Hosokawa, M.3
  • 24
    • 0034198971 scopus 로고    scopus 로고
    • Effects of hepatic artery chemotherapeutic embolization combined with perfusing LAK cells into hepatic artery after radical operation of liver cancer
    • Xie L, Pang R, Jin Y, et al., [Effects of hepatic artery chemotherapeutic embolization combined with perfusing LAK cells into hepatic artery after radical operation of liver cancer]. Zhonghua Gan Zang Bing Za Zhi 2000; 8: 142-3.
    • (2000) Zhonghua Gan Zang Bing Za Zhi , vol.8 , pp. 142-143
    • Xie, L.1    Pang, R.2    Jin, Y.3
  • 25
    • 79952276385 scopus 로고    scopus 로고
    • Therapeutic safety and effects of adjuvant autologous RetroNectin activated killer cell immunotherapy for patients with primary hepatocellular carcinoma after radiofrequency ablation
    • Ma H, Zhang Y, Wang Q, et al., Therapeutic safety and effects of adjuvant autologous RetroNectin activated killer cell immunotherapy for patients with primary hepatocellular carcinoma after radiofrequency ablation. Cancer Biol Ther 2010; 9: 903-7.
    • (2010) Cancer Biol Ther , vol.9 , pp. 903-907
    • Ma, H.1    Zhang, Y.2    Wang, Q.3
  • 26
    • 0030993778 scopus 로고    scopus 로고
    • Postoperative immunotherapy for patients with hepatocarcinoma using tumor-infiltrating lymphocytes
    • Wang Y, Chen H, Wu M, et al., Postoperative immunotherapy for patients with hepatocarcinoma using tumor-infiltrating lymphocytes. Chin Med J (Engl) 1997; 110: 114-7. (Pubitemid 27139428)
    • (1997) Chinese Medical Journal , vol.110 , Issue.2 , pp. 114-117
    • Wang, Y.1    Chen, H.2    Wu, M.3    Bao, J.4    Cong, W.5    Wang, H.6
  • 27
    • 16544376204 scopus 로고    scopus 로고
    • Long-term prognosis of hepatocellular carcinoma patients treated with adoptive immunotherapy
    • Takeda T, Watanabe M, Umeshita K, et al., [Long-term prognosis of hepatocellular carcinoma patients treated with adoptive immunotherapy]. Gan To Kagaku Ryoho 2004; 31: 1646-8.
    • (2004) Gan to Kagaku Ryoho , vol.31 , pp. 1646-1648
    • Takeda, T.1    Watanabe, M.2    Umeshita, K.3
  • 28
    • 33749608763 scopus 로고    scopus 로고
    • Medical treatments for hepatocellular carcinoma (HCC): What's next?
    • DOI 10.1093/annonc/mdl279
    • Taieb J, Barbare JC, Rougier P,. Medical treatments for hepatocellular carcinoma (HCC): what's next? Ann Oncol 2006; 17 (Suppl 10): x308-14. (Pubitemid 44542028)
    • (2006) Annals of Oncology , vol.17 , Issue.SUPPL. 10
    • Taieb, J.1    Barbare, J.C.2    Rougier, P.3
  • 29
    • 0036242370 scopus 로고    scopus 로고
    • Current status of adoptive immunotherapy of malignancies
    • DOI 10.1517/14712598.2.3.237
    • Morse MA, Clay TM, Lyerly HK,. Current status of adoptive immunotherapy of malignancies. Expert Opin Biol Ther 2002; 2: 237-47. (Pubitemid 34464806)
    • (2002) Expert Opinion on Biological Therapy , vol.2 , Issue.3 , pp. 237-247
    • Morse, M.A.1    Clay, T.M.2    Lyerly, H.K.3
  • 30
    • 3042534233 scopus 로고    scopus 로고
    • Adoptive immunotherapy of cancer using activated autologous lymphocytes - Current status and new strategies
    • Yamaguchi Y, Ohshita A, Kawabuchi Y, et al., Adoptive immunotherapy of cancer using activated autologous lymphocytes - current status and new strategies. Hum Cell 2003; 16: 183-9.
    • (2003) Hum Cell , vol.16 , pp. 183-189
    • Yamaguchi, Y.1    Ohshita, A.2    Kawabuchi, Y.3
  • 32
    • 0036378352 scopus 로고    scopus 로고
    • Treatment of non-resectable hepatocellular carcinoma with autologous tumor-pulsed dendritic cells
    • Ladhams A, Schmidt C, Sing G, et al., Treatment of non-resectable hepatocellular carcinoma with autologous tumor-pulsed dendritic cells. J Gastroenterol Hepatol 2002; 17: 889-96.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 889-896
    • Ladhams, A.1    Schmidt, C.2    Sing, G.3
  • 33
    • 33845948119 scopus 로고    scopus 로고
    • Adoptive transfer of TRAIL-expressing natural killer cells prevents recurrence of hepatocellular carcinoma after partial hepatectomy
    • DOI 10.1097/01.tp.0000250935.41034.2d, PII 0000789020061227000036
    • Ohira M, Ohdan H, Mitsuta H, et al., Adoptive transfer of TRAIL-expressing natural killer cells prevents recurrence of hepatocellular carcinoma after partial hepatectomy. Transplantation 2006; 82: 1712-9. (Pubitemid 46035657)
    • (2006) Transplantation , vol.82 , Issue.12 , pp. 1712-1719
    • Ohira, M.1    Ohdan, H.2    Mitsuta, H.3    Ishiyama, K.4    Tanaka, Y.5    Igarashi, Y.6    Asahara, T.7
  • 34
    • 0344875955 scopus 로고    scopus 로고
    • Changes of immune function in patients with liver cirrhosis after splenectomy combined with resection of hepatocellular carcinoma
    • Cao ZX, Chen XP, Wu ZD,. Changes of immune function in patients with liver cirrhosis after splenectomy combined with resection of hepatocellular carcinoma. Hepatobiliary Pancreat Dis Int 2003; 2: 562-5.
    • (2003) Hepatobiliary Pancreat Dis Int , vol.2 , pp. 562-565
    • Cao, Z.X.1    Chen, X.P.2    Wu, Z.D.3
  • 35
    • 3042720174 scopus 로고    scopus 로고
    • Immune escape mechanism: Defective resting and stimulated leukocyte-endothelium interaction in hepatocellular carcinoma of the rat
    • DOI 10.1023/B:DDAS.0000030100.05979.b7
    • Maksan SM, Araib PM, Ryschich E, et al., Immune escape mechanism: defective resting and stimulated leukocyte-endothelium interaction in hepatocellular carcinoma of the rat. Dig Dis Sci 2004; 49: 859-65. (Pubitemid 38870215)
    • (2004) Digestive Diseases and Sciences , vol.49 , Issue.5 , pp. 859-865
    • Maksan, S.-M.1    Araib, P.M.2    Ryschich, E.3    Gebhard, M.M.4    Schmidt, J.5
  • 37
    • 0033791029 scopus 로고    scopus 로고
    • Spontaneous regression of hepatocellular carcinoma
    • Okada S, Abo T,. Spontaneous regression of hepatocellular carcinoma. J Gastroenterol Hepatol 2000; 15: 965-6.
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 965-966
    • Okada, S.1    Abo, T.2
  • 39
    • 67650360317 scopus 로고    scopus 로고
    • Immunotherapy with cytokine induced killer cells in solid and hematopoietic tumours: A pilot clinical trial
    • Olioso P, Giancola R, Di Riti M, et al., Immunotherapy with cytokine induced killer cells in solid and hematopoietic tumours: a pilot clinical trial. Hematol Oncol 2009; 27: 130-9.
    • (2009) Hematol Oncol , vol.27 , pp. 130-139
    • Olioso, P.1    Giancola, R.2    Di Riti, M.3
  • 40
    • 55249097842 scopus 로고    scopus 로고
    • Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients
    • Cai L, Zhang Z, Zhou L, et al., Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients. Clin Immunol 2008; 129: 428-37.
    • (2008) Clin Immunol , vol.129 , pp. 428-437
    • Cai, L.1    Zhang, Z.2    Zhou, L.3
  • 42
    • 0942300581 scopus 로고    scopus 로고
    • Effects of Pulsing Procedure of Interleukin-12 in Combination with Interleukin-2 on the Activation of Peripheral Blood Lymphocytes Derived from Patients with Hepatocellular Carcinoma
    • Sawayama T, Sakaguchi K, Senoh T, et al., Effects of pulsing procedure of interleukin-12 in combination with interleukin-2 on the activation of peripheral blood lymphocytes derived from patients with hepatocellular carcinoma. Acta Med Okayama 2003; 57: 285-92. (Pubitemid 38142749)
    • (2003) Acta Medica Okayama , vol.57 , Issue.6 , pp. 285-292
    • Sawayama, T.1    Sakaguchi, K.2    Senoh, T.3    Ohta, T.4    Nishimura, M.5    Takaki, A.6    Tsuji, T.7    Shiratori, Y.8
  • 44
    • 77951689275 scopus 로고    scopus 로고
    • Radiofrequency thermal ablation for hepatocellular carcinoma stimulates autologous NK-cell response
    • Zerbini A, Pilli M, Laccabue D, et al., Radiofrequency thermal ablation for hepatocellular carcinoma stimulates autologous NK-cell response. Gastroenterology 2010; 138: 1931-42.
    • (2010) Gastroenterology , vol.138 , pp. 1931-1942
    • Zerbini, A.1    Pilli, M.2    Laccabue, D.3
  • 45
    • 79953063490 scopus 로고    scopus 로고
    • Possibility of adoptive immunotherapy with peripheral blood-derived CD3CD56 + and CD3 + CD56 + cells for inducing antihepatocellular carcinoma and antihepatitis C virus activity
    • Doskali M, Tanaka Y, Ohira M, et al., Possibility of adoptive immunotherapy with peripheral blood-derived CD3CD56 + and CD3 + CD56 + cells for inducing antihepatocellular carcinoma and antihepatitis C virus activity. J Immunother 2011; 34: 129-38.
    • (2011) J Immunother , vol.34 , pp. 129-138
    • Doskali, M.1    Tanaka, Y.2    Ohira, M.3
  • 46
    • 63949086950 scopus 로고    scopus 로고
    • The immunosuppressive tumor microenvironment in hepatocellular carcinoma
    • Pang YL, Zhang HG, Peng JR, et al., The immunosuppressive tumor microenvironment in hepatocellular carcinoma. Cancer Immunol Immunother 2009; 58: 877-86.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 877-886
    • Pang, Y.L.1    Zhang, H.G.2    Peng, J.R.3
  • 48
    • 67349100632 scopus 로고    scopus 로고
    • Transfusion of autologous cytokine-induced killer cells inhibits viral replication in patients with chronic hepatitis B virus infection
    • Shi M, Fu J, Shi F, et al., Transfusion of autologous cytokine-induced killer cells inhibits viral replication in patients with chronic hepatitis B virus infection. Clin Immunol 2009; 132: 43-54.
    • (2009) Clin Immunol , vol.132 , pp. 43-54
    • Shi, M.1    Fu, J.2    Shi, F.3
  • 49
    • 47949116252 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocellular carcinoma
    • Llovet JM, Ricci S, Mazzaferro V, et al., Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378-90.
    • (2008) N Engl J Med , vol.359 , pp. 378-390
    • Llovet, J.M.1    Ricci, S.2    Mazzaferro, V.3
  • 50
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
    • Cheng AL, Kang YK, Chen Z, et al., Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009; 10: 25-34.
    • (2009) Lancet Oncol , vol.10 , pp. 25-34
    • Cheng, A.L.1    Kang, Y.K.2    Chen, Z.3
  • 51
    • 78751507840 scopus 로고    scopus 로고
    • Emerging strategies in the treatment of advanced hepatocellular carcinoma: The role of targeted therapies
    • Lord R, Suddle A, Ross PJ,. Emerging strategies in the treatment of advanced hepatocellular carcinoma: the role of targeted therapies. Int J Clin Pract 2011; 65: 182-8.
    • (2011) Int J Clin Pract , vol.65 , pp. 182-188
    • Lord, R.1    Suddle, A.2    Ross, P.J.3
  • 52
    • 77953820596 scopus 로고    scopus 로고
    • Design and rationale for the non-interventional Global Investigation of Therapeutic DEcisions in Hepatocellular Carcinoma and of its Treatment with Sorafenib (GIDEON) study
    • Lencioni R, Marrero J, Venook A, Ye SL, Kudo M,. Design and rationale for the non-interventional Global Investigation of Therapeutic DEcisions in Hepatocellular Carcinoma and Of its Treatment with Sorafenib (GIDEON) study. Int J Clin Pract 2010; 64: 1034-41.
    • (2010) Int J Clin Pract , vol.64 , pp. 1034-1041
    • Lencioni, R.1    Marrero, J.2    Venook, A.3    Ye, S.L.4    Kudo, M.5
  • 53
    • 77956269017 scopus 로고    scopus 로고
    • Radiofrequency ablation for the treatment of HCC - Maybe much more than simple tumor destruction?
    • Greten TF, Korangy F,. Radiofrequency ablation for the treatment of HCC - maybe much more than simple tumor destruction? J Hepatol 2010; 53: 775-6.
    • (2010) J Hepatol , vol.53 , pp. 775-776
    • Greten, T.F.1    Korangy, F.2


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