Circulating ApoE level is independently associated with urinary albumin excretion in type 2 diabetic patients

Internal Medicine

Volumn 50, Issue 24, 2011, Pages 2961-2966

  Ling, Yan ^a   Li, Xiaomu ^a   Gu, Qian ^a   Gao, Xin ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Apolipoprotein E; Lipids; Type 2 diabetes; Urinary albumin

Indexed keywords

ALBUMIN; ANGIOTENSIN RECEPTOR ANTAGONIST; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; APOLIPOPROTEIN E; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FIBRIC ACID DERIVATIVE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN CHOLESTEROL; STATIN;

ADULT; ARTICLE; BLOOD PRESSURE; BODY HEIGHT; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE URINE LEVEL; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; FEMALE; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; HUMAN; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MICROALBUMINURIA; NON INSULIN DEPENDENT DIABETES MELLITUS; TRIACYLGLYCEROL BLOOD LEVEL;

ALBUMINURIA; APOLIPOPROTEINS E; CHINA; CREATININE; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; FEMALE; HUMANS; MALE; MIDDLE AGED; RISK FACTORS;

EID: 83755173684     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.50.6216     Document Type: Article

References (32)

1. Coonrod BA, Ellis D, Becker DJ, et al. Predictors of microalbuminuria in individuals with IDDM. Pittsburgh Epidemiology of Diabetes Complications Study. Diabetes Care 16: 1376-1383, 1993.
2. Dominguez JH, Tang N, Xu W, et al. Studies of renal injury III: lipid-induced nephropathy in type II diabetes. Kidney Int 57: 92-104, 2000.
3. Jenkins AJ, Lyons TJ, Zheng D, et al; DCCT/EDIC Research Group. Lipoproteins in the DCCT/EDIC cohort: associations with diabetic nephropathy. Kidney Int 64: 817-828, 2003.
4. Tolonen N, Forsblom C, Thorn L, et al. Lipid abnormalities predict progression of renal disease in patients with type 1 diabetes. Diabetologia 52: 2522-2530, 2009.
5. Hirano T, Sakaue T, Misaki A, et al. Very low-density lipoproteinapoprotein CI is increased in diabetic nephropathy: comparison with apoprotein CIII. Kidney Int 63: 2171-2177, 2003.
6. Ding G, van Goor H, Ricardo SD, Orlowski JM, Diamond JR. Oxidized LDL stimulates the expression of TGF-beta and fibronectin in human glomerular epithelial cells. Kidney Int 51: 147-154, 1997.
7. Nakhjavani M, Esteghamati A, Khalilzadeh O, Asgarani F, Mansournia N, Abbasi M. Association of macroalbuminuria with oxidized LDL and TGF-beta in type 2 diabetic patients: a casecontrol study. Int Urol Nephrol 42: 487-492, 2010.
8. Nieuwdorp M, Mooij HL, Kroon J, et al. Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes. Diabetes 55: 1127-1132, 2006.
9. Singh A, Satchell SC, Neal CR, McKenzie EA, Tooke JE, Mathieson PW. Glomerular endothelial glycocalyx constitutes a barrier to protein permeability. J Am Soc Nephrol 18: 2885-2893, 2007.
10. Abrass CK. Cellular lipid metabolism and the role of lipids in progressive renal disease. Am J Nephrol 24: 46-53, 2004.
11. Tseng CH. Lipid abnormalities associated with urinary albumin excretion rate in Taiwanese type 2 diabetic patients. Kidney Int 67: 1547-1553, 2005.
12. Tseng CH. Differential dyslipidemia associated with albuminuria in type 2 diabetic patients in Taiwan. Clin Biochem 42: 1019-1024, 2009.
13. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15: 539-553, 1998.
14. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 16: 31-41, 1976.
15. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18: 499-502, 1972.
16. Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240: 622-630, 1988.
17. Eichner JE, Dunn ST, Perveen G, Thompson DM, Stewart KE, Stroehla BC. Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review. Am J Epidemiol 155: 487-495, 2002.
18. Ashford JW. APOE genotype effects on Alzheimer's disease onset and epidemiology. J Mol Neurosci 23: 157-165, 2004.
19. Saito T, Matsunaga A, Oikawa S. Impact of lipoprotein glomerulopathy on the relationship between lipids and renal diseases. Am J Kidney Dis 47: 199-211, 2006.
20. Yorioka N, Nishida Y, Oda H, Watanabe T, Yamakido M. Apolipoprotein E polymorphism in IgA nephropathy. Nephron 83: 246-249, 1999.
21. Asami T, Ciomartan T, Hayakawa H, Uchiyama M, Tomisawa S. Apolipoprotein E epsilon 4 allele and nephrotic glomerular diseases in children. Pediatr Nephrol 13: 233-236, 1999.
22. Mooyaart AL, Valk EJ, van Es LA, et al. Genetic associations in diabetic nephropathy: a meta-analysis. Diabetologia 54: 544-553, 2011.
23. Li Y, Tang K, Zhang Z, et al. Genetic diversity of the apolipoprotein E gene and diabetic nephropathy: a meta-analysis. Mol Biol Rep 38: 3243-3252, 2011.
24. Liberopoulos EN, Miltiadous GA, Cariolou M, Tselepis AD, Siamopoulos KC, Elisaf MS. The influence of serum apolipoprotein E concentration and polymorphism on serum lipid parameters in hemodialysis patients. Am J Kidney Dis 44: 300-308, 2004.
25. Haddy N, De Bacquer D, Chemaly MM, et al. The importance of plasma apolipoprotein E concentration in addition to its common polymorphism on inter-individual variation in lipid levels: results from Apo Europe. Eur J Hum Genet 10: 841-850, 2002.
26. Attman PO, Knight-Gibson C, Tavella M, Samuelsson O, Alaupovic P. The compositional abnormalities of lipoproteins in diabetic renal failure. Nephrol Dial Transplant 13: 2833-2841, 1998.
27. Kim HJ, Cho EH, Yoo JH, et al. Proteome analysis of serum from type 2 diabetics with nephropathy. J Proteome Res 6: 735-743, 2007.
28. Liberopoulos E, Siamopoulos K, Elisaf M. Apolipoprotein E and renal disease. Am J Kidney Dis 43: 223-233, 2004.
29. Chen G, Paka L, Kako Y, Singhal P, Duan W, Pillarisetti S. A protective role for kidney apolipoprotein E. Regulation of mesangial cell proliferation and matrix expansion. J Biol Chem 276: 49142-49147, 2001.
30. Chan MK, Persaud JW, Ramdial L, Varghese Z, Sweny P, Moorhead JF. Hyperlipidaemia in untreated nephrotic syndrome, increased production or decreased removal? Clin Chim Acta 117: 317-323, 1981.
31. Lee DM, Knight-Gibson C, Samuelsson O, Attman PO, Wang CS, Alaupovic P. Lipoprotein particle abnormalities and the impaired lipolysis in renal insufficiency. Kidney Int 61: 209-218, 2002.
32. Chasman DI, Kozlowski P, Zee RY, Kwiatkowski DJ, Ridker PM. Qualitative and quantitative effects of APOE genetic variation on plasma C-reactive protein, LDL-cholesterol, and apoE protein. Genes Immun 7: 211-219, 2006.