Potentiation of tumor radiotherapy by a radiation-inducible oncolytic and oncoapoptotic adenovirus in cervical cancer xenografts

International Journal of Cancer

Volumn 130, Issue 2, 2012, Pages 443-453

  Wang, Haibo ^a,b   Song, Xin ^a   Zhang, He ^a,b   Zhang, Jianjun ^a   Shen, Xiaodi ^a   Zhou, Yixiong ^a   Fan, Xianqun ^a   Dai, Liyan ^a   Qian, Guanxiang ^a   Hoffman, Andrew R ^b   Hu, Ji Fan ^b   Ge, Shengfang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

adenovirus; apoptosis; Egr 1 promoter; gene therapy; radiotherapy; TRAIL; tumor

Indexed keywords

CASPASE 3; CASPASE 8; EARLY GROWTH RESPONSE FACTOR 1; ONCOLYTIC ADENOVIRUS; PROTEIN P53; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER RADIOTHERAPY; CANCER SURVIVAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RADIATION DOSE; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR XENOGRAFT; UTERINE CERVIX CANCER;

ADENOVIRUSES, HUMAN; ANIMALS; APOPTOSIS; COMBINED MODALITY THERAPY; EARLY GROWTH RESPONSE PROTEIN 1; FEMALE; HELA CELLS; HUMANS; MICE; MICE, NUDE; ONCOLYTIC VIROTHERAPY; PROMOTER REGIONS, GENETIC; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS; VIRUS ACTIVATION; VIRUS REPLICATION;

EID: 83655192074     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26013     Document Type: Article

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