A portable fiberoptic ratiometric fluorescence analyzer provides rapid point-of-care determination of glomerular filtration rate in large animals

Kidney International

Volumn 81, Issue 1, 2012, Pages 112-117

  Wang, Exing ^a   Meier, Daniel J ^b   Sandoval, Ruben M ^a   Von Hendy Willson, Vanessa E ^c   Pressler, Barrak M ^c   Bunch, Robert M ^d   Alloosh, Mouhamad ^a   Sturek, Michael S ^a   Schwartz, George J ^e   Molitoris, Bruce A ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FAST   (United States)

^c PURDUE UNIVERSITY   (United States)

^d ROSE HULMAN INSTITUTE OF TECHNOLOGY   (United States)

^e UNIVERSITY OF ROCHESTER   (United States)

Author keywords

acute kidney injury; chronic kidney disease; glomerular filtration rate

Indexed keywords

DEXTRAN; INULIN; IOHEXOL;

ANIMAL EXPERIMENT; ARTICLE; CHIMERA; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DOG; FEMALE; FIBER OPTICS; FLUORESCENCE; GLOMERULUS FILTRATION RATE; KIDNEY CLEARANCE; KIDNEY FUNCTION; LIGHT EMITTING DIODE; NONHUMAN; PERIPHERAL VEIN; POINT OF CARE TESTING; PRIORITY JOURNAL; SWINE;

EID: 83655167299     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.294     Document Type: Article

References (29)

1. Dagher PC, Herget-Rosenthal S, Ruehm SG et al. Newly developed techniques to study and diagnose acute renal failure. J Am Soc Nephrol 2003; 14: 2188-2198. (Pubitemid 36909929)
2. Himmelfarb J, Joannidis M, Molitoris B et al. Evaluation and initial management of acute kidney injury. Clin J Am Soc Nephrol 2008; 3: 962-967.
3. Ishani A, Xue JL, Himmelfarb J et al. Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol 2009; 20: 223-228.
4. Madder RDMD, Hickman LP, Crimmins GMMD et al. Validity of estimated glomerular filtration rates for assessment of baseline and serial renal function in patients with atherosclerotic renal artery stenosis: implications for clinical trials of renal revascularization. Circ Cardiovasc Interv 2011; 4: 219-225.
5. Stevens LA, Coresh J, Greene T et al. Assessing kidney function-measured and estimated glomerular filtration rate. N Engl J Med 2006; 354: 2473-2483. (Pubitemid 43855050)
6. Watnick T, Germino GG. mTOR inhibitors in polycystic kidney disease. N Engl J Med 2010; 363: 879-881.
7. Wang E, Sandoval RM, Campos SB et al. Rapid diagnosis and quantification of acute kidney injury using fluorescent ratio-metric determination of glomerular filtration rate in the rat. Am J Physiol Renal Physiol 2010; 299: F1048-F1055.
8. Vogt Jr. R.F, Marti GE, Zenger V. Quantitative fluorescence calibration: a tool for assessing the quality of data obtained by fluorescence measurements. In: Resch-Genger U (ed). Standardization and Quality Assurance in Fluorescence Measurements I, vol. 5 Springer: Berlin, Heidelberg, 2008, pp 3-31.
9. Yu W, Sandoval RM, Molitoris BA. Rapid determination of renal filtration function using an optical ratiometric imaging approach. Am J Physiol Renal Physiol 2007; 292: F1873-F1880. (Pubitemid 47105377)
10. Mehvar R, Shepard TL. Molecular-weight-dependent pharmacokinetics of fluorescein-labeled dextrans in rats. J Pharm Sci 1992; 81: 908-912. (Pubitemid 23006844)
11. Molitoris BA, Melnikov VY, Okusa MD et al. Technology insight: biomarker development in acute kidney injury-what can we anticipate? Nat Clin Pract Nephrol 2008; 4: 154-165. (Pubitemid 351312080)
12. Rabito CA, Chen Y, Schomacker KT et al. Optical, real-time monitoring of the glomerular filtration rate. Appl Optics 2005; 44: 5956-5965. (Pubitemid 41686402)
13. Rabito CA, Moore RH, Bougas C et al. Noninvasive, real-time monitoring of renal function: the ambulatory renal monitor [see comment]. J Nuclear Med 1993; 34: 199-207. (Pubitemid 23056397)
14. Rabito CA, Panico F, Rubin R et al. Noninvasive, real-time monitoring of renal function during critical care. J Am Soc Nephrol 1994; 4: 1421-1428.
15. Schock-Kusch D, Sadick M, Henninger N et al. Transcutaneous measurement of glomerular filtration rate using FITC-sinistrin in rats. Nephrol Dial Transplant 2009; 24: 2997-3001.
16. Schock-Kusch D, Xie Q, Shulhevich Y et al. Transcutaneous assessment of renal function in conscious rats with a device for measuring FITC-sinistrin disappearance curves. Kidney Int 2011; 79: 1254-1258.
17. Cole BR, Giangiacomo J, Ingelfinger JR et al. Measurement of renal function without urine collection. N Engl J Med 1972; 287: 1109-1114.
18. Holliday MA, Heilbron D, Al-Uzri A et al. Serial measurements of GFR in infants using the continuous iothalamate infusion technique. Kidney Int 1993; 43: 893-898. (Pubitemid 23105224)
19. Pedersen JF, Madsen PO. Simultaneous determination of glomerular filtration rate and effective plasma flow by external monitoring of radioisotopes. An experimental study in dogs. Invest Urol 1970; 8: 203-209.
20. Ljungström KG. Safety of dextran in relation to other colloids-ten years experience with hapten inhibition. Infusionstherapie und Transfusionsmedizin 1993; 20: 206-210.
21. Murphy JT, Horton JW, Purdue GF et al. Cardiovascular effect of 7.5% sodium chloride-dextran infusion after thermal injury. Arch Surg 1999; 134: 1091-1097. (Pubitemid 29473198)
22. Zinderman CE, Landow L, Wise RP. Anaphylactoid reactions to Dextran 40 and 70: Reports to the United States Food and Drug Administration, 1969-2004. J Vasc Surg 2006; 43: 1004-1009.
23. AVMA Panel on Euthanasia. 2000 Report of the AVMA Panel on Euthanasia. J Am Vet Med Assoc 2001; 218: 669-696.
24. Institute for Laboratory Animal Research. Guide for the Care and Use of Laboratory Animals. National Academy Press: Washington, DC, 2010.
25. Schwartz GJ, Abraham AG, Furth SL et al. Optimizing iohexol plasma disappearance curves to measure the glomerular filtration rate in children with chronic kidney disease. Kidney Int 2009; 77: 65-71.
26. Schwartz GJ, Furth S, Cole SR et al. Glomerular filtration rate via plasma iohexol disappearance: pilot study for chronic kidney disease in children. Kidney Int 2006; 69: 2070-2077. (Pubitemid 43924273)
27. Qi Z, Whitt I, Mehta A et al. Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance. Am J Physiol Renal Physiol 2004; 286: F590-F596. (Pubitemid 38233654)
28. Sapirstein LA, Vidt DG, Mandel MJ et al. Volumes of distribution and clearances of intravenously injected creatinine in the dog. Am J Physiol 1955; 181: 330-336.
29. Sturgeon C, Sam II AD, Law WR. Rapid determination of glomerular filtration rate by single-bolus inulin: a comparison of estimation analyses. J Appl Physiol 1998; 84: 2154-2162. (Pubitemid 28255979)