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Volumn 23, Issue 1, 2012, Pages 9-14

Non-dietary therapeutic clinical trials in coeliac disease

Author keywords

Coeliac disease; Gluten free diet; Glutenases; Larazotide; Treatment

Indexed keywords

ALV 003; AN PEP; CCX 282B; GLUTEN; IMMUNOMODULATING AGENT; LARAZOTIDE; NEXVAX 2; PROTEINASE; TRAFICET EN; UNCLASSIFIED DRUG; VACCINE;

EID: 83555173695     PISSN: 09536205     EISSN: 18790828     Source Type: Journal    
DOI: 10.1016/j.ejim.2011.08.030     Document Type: Short Survey
Times cited : (36)

References (40)
  • 5
    • 0041669320 scopus 로고    scopus 로고
    • Coeliac disease
    • DOI 10.1016/S0140-6736(03)14027-5
    • P.H. Green, and B. Jabri Coeliac disease Lancet 362 2003 383 391 (Pubitemid 36945070)
    • (2003) Lancet , vol.362 , Issue.9381 , pp. 383-391
    • Green, P.H.R.1    Jabri, B.2
  • 6
    • 70649092298 scopus 로고    scopus 로고
    • Celiac disease: From pathogenesis to novel therapies
    • D. Schuppan, Y. Junker, and D. Barisani Celiac disease: from pathogenesis to novel therapies Gastroenterology 137 2009 1912 1933
    • (2009) Gastroenterology , vol.137 , pp. 1912-1933
    • Schuppan, D.1    Junker, Y.2    Barisani, D.3
  • 11
    • 0037072829 scopus 로고    scopus 로고
    • Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the influence on the transamidation versus deamidation process
    • B. Fleckenstein, O. Molberg, S.W. Qiao, D.G. Schmid, and F. von der Mülbe Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the influence on the transamidation versus deamidation process J Biol Chem 277 2002 34109 34116
    • (2002) J Biol Chem , vol.277 , pp. 34109-34116
    • Fleckenstein, B.1    Molberg, O.2    Qiao, S.W.3    Schmid, D.G.4    Von Der Mülbe, F.5
  • 13
  • 14
    • 0032528813 scopus 로고    scopus 로고
    • Cutting edge: Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity
    • Y. Van de Wal, Y. Kooy, P. Van Veelen, S. Peña, L. Mearin, and G. Papadopoulos Selective deamination by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity J Immunol 161 1998 1585 1588 (Pubitemid 28387571)
    • (1998) Journal of Immunology , vol.161 , Issue.4 , pp. 1585-1588
    • Van De Wal, Y.1    Kooy, Y.2    Van Veelen, P.3    Pena, S.4    Mearin, L.5    Papadopoulos, G.6    Koning, F.7
  • 15
    • 0042324662 scopus 로고    scopus 로고
    • Alterations of the intestinal transport and processing of gliadin peptides in celiac disease
    • DOI 10.1016/S0016-5085(03)01049-7
    • T. Matysiak-Budnik, C. Candalh, C. Dugave, A. Namane, C. Cellier, and N. Cerf-Bensussan Alterations of the intestinal transport and processing of gliadin peptides in celiac disease Gastroenterology 125 2003 696 707 (Pubitemid 37070688)
    • (2003) Gastroenterology , vol.125 , Issue.3 , pp. 696-707
    • Matysiak-Budnik, T.1    Candalh, C.2    Dugave, C.3    Namane, A.4    Cellier, C.5    Cerf-Bensussan, N.6    Heyman, M.7
  • 16
    • 0031944553 scopus 로고    scopus 로고
    • Epithelial tight junction structure in the jejunum of children with acute and treated celiac sprue
    • J.D. Schulzke, C.J. Bentzel, I. Schulzke, E.O. Riecken, and M. Fromm Epithelial tight junction structure in the jejunum of children with acute and treated celiac sprue Pediatr Res 43 1998 435 441 (Pubitemid 28157949)
    • (1998) Pediatric Research , vol.43 , Issue.4 , pp. 435-441
    • Schulzke, J.-D.1    Bentzel, C.J.2    Schulzke, I.3    Riecken, E.-O.4    Fromm, M.5
  • 18
    • 79952389800 scopus 로고    scopus 로고
    • Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens
    • R.W. DePaolo, V. Abadie, F. Tang, H. Fehlner-Peach, J.A. Hall, and W. Wang Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens Nature 471 2011 220 224
    • (2011) Nature , vol.471 , pp. 220-224
    • Depaolo, R.W.1    Abadie, V.2    Tang, F.3    Fehlner-Peach, H.4    Hall, J.A.5    Wang, W.6
  • 20
    • 0037328941 scopus 로고    scopus 로고
    • Duodenal histology in patients with celiac disease after treatment with a gluten-free diet
    • DOI 10.1067/mge.2003.54
    • S.K. Lee, W. Lo, L. Memeo, H. Rotterdam, and P.H. Green Duodenal histology in patients with celiac disease after treatment with a gluten-free diet Gastrointest Endosc 57 2003 187 191 (Pubitemid 36236757)
    • (2003) Gastrointestinal Endoscopy , vol.57 , Issue.2 , pp. 187-191
    • Lee, S.K.1    Lo, W.2    Memeo, L.3    Rotterdam, H.4    Green, P.H.R.5
  • 21
    • 33646247420 scopus 로고    scopus 로고
    • Oats in the treatment of childhood celiac disease: A 2 year controlled trial and a long term follow up study
    • K. Holm, M. Maki, K. Vuolteenaho, K. Mustalahti, M. Ashorn, and T. Ruuska Oats in the treatment of childhood celiac disease: a 2 year controlled trial and a long term follow up study Aliment Pharmacol Ther 23 2006 1463 1472
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1463-1472
    • Holm, K.1    Maki, M.2    Vuolteenaho, K.3    Mustalahti, K.4    Ashorn, M.5    Ruuska, T.6
  • 22
    • 16244375839 scopus 로고    scopus 로고
    • Dietary guidelines and implementation for celiac disease
    • C. Kupper Dietary guidelines and implementation for celiac disease Gastroenterology 128 2005 S124 S127
    • (2005) Gastroenterology , vol.128
    • Kupper, C.1
  • 24
    • 76049102125 scopus 로고    scopus 로고
    • Complete recovery of intestinal mucosa occurs very rarely in adult celiac patients despite adherence to gluten-free diet
    • A. Lanzini, F. Lanzarotto, V. Villanacci, A. Mora, S. Bertolazzi, and D. Turini Complete recovery of intestinal mucosa occurs very rarely in adult celiac patients despite adherence to gluten-free diet Aliment Pharmacol Ther 29 2009 1299 1308
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 1299-1308
    • Lanzini, A.1    Lanzarotto, F.2    Villanacci, V.3    Mora, A.4    Bertolazzi, S.5    Turini, D.6
  • 25
    • 42949120968 scopus 로고    scopus 로고
    • Systematic review: Tolerable amount of gluten for people with coeliac disease
    • DOI 10.1111/j.1365-2036.2008.03669.x
    • A.K. Akobeng, and A.G. Thomas Systematic review: tolerable amount of gluten for people with coeliac disease Aliment Pharmacol Ther 27 2008 1044 1052 (Pubitemid 351614885)
    • (2008) Alimentary Pharmacology and Therapeutics , vol.27 , Issue.11 , pp. 1044-1052
    • Akobeng, A.K.1    Thomas, A.G.2
  • 26
    • 33749826082 scopus 로고    scopus 로고
    • Consumption of gluten-free products: Should the threshold value for trace amounts of gluten be at 20, 100 or 200 p.p.m.?
    • DOI 10.1097/01.meg.0000236884.21343.e4, PII 0004273720061100000012
    • A. Gibert, M. Espadaler, A. Canela, A. Sánchez, C. Vaqué, and M. Rafecas Consumption of gluten-free products: should the threshold value for trace amounts of gluten be 20, 100 or 200 ppm? Eur J Gastroenterol Hepatol 18 2006 1187 1195 (Pubitemid 44563879)
    • (2006) European Journal of Gastroenterology and Hepatology , vol.18 , Issue.11 , pp. 1187-1195
    • Gibert, A.1    Espadaler, M.2    Angel Canela, M.3    Sanchez, A.4    Vaque, C.5    Rafecas, M.6
  • 27
    • 34547852241 scopus 로고    scopus 로고
    • The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: A proof of concept study
    • DOI 10.1111/j.1365-2036.2007.03413.x
    • B.M. Paterson, K.M. Lammers, M.C. Arrieta, A. Fasano, and J.B. Meddings The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: a proof of concept study Aliment Pharmacol Ther 26 2007 757 766 (Pubitemid 47246202)
    • (2007) Alimentary Pharmacology and Therapeutics , vol.26 , Issue.5 , pp. 757-766
    • Paterson, B.M.1    Lammers, K.M.2    Arrieta, M.C.3    Fasano, A.4    Meddings, J.B.5
  • 28
    • 0031051849 scopus 로고    scopus 로고
    • The enterotoxic effect of zonula occludens toxin on rabbit small intestine involves the paracellular pathway
    • DOI 10.1053/gast.1997.v112.pm9041245
    • A. Fasano, S. Uzzau, C. Fiore, and K. Margaretten The enterotoxic effect on zonula occludens toxin on rabbit small intestine involves the paracellular pathway Gastroenterology 112 1997 839 846 (Pubitemid 27113809)
    • (1997) Gastroenterology , vol.112 , Issue.3 , pp. 839-846
    • Fasano, A.1    Uzzau, S.2    Fiore, C.3    Margaretten, K.4
  • 29
    • 0345268671 scopus 로고    scopus 로고
    • Zonula occludens toxin acts as an adjuvant through different mucosal routes and induces protective immune responses
    • DOI 10.1128/IAI.71.4.1897-1902.2003
    • M. Marinaro, A. Fasano, and M.T. De Magistris Zonula occludens toxin acts as an adjuvant through different mucosal routes and induces protective immune responses Infect Immun 71 2003 1897 1902 (Pubitemid 36368721)
    • (2003) Infection and Immunity , vol.71 , Issue.4 , pp. 1897-1902
    • Marinaro, M.1    Fasano, A.2    De Magistris, M.T.3
  • 30
    • 77950866443 scopus 로고    scopus 로고
    • Effect of larazotide acetate on the prevention of signs and symptoms of coeliac disease in patients undergoing a gluten challenge: A randomised placebo-controlled study
    • C.P. Kelly, P.H.R. Green, J.A. Murray, A. Di Marino, A. Colatrella, and D.A. Leffler Effect of larazotide acetate on the prevention of signs and symptoms of coeliac disease in patients undergoing a gluten challenge: a randomised placebo-controlled study Gastroenterology 136 2009 M2048
    • (2009) Gastroenterology , vol.136 , pp. 2048
    • Kelly, C.P.1    Green, P.H.R.2    Murray, J.A.3    Di Marino, A.4    Colatrella, A.5    Leffler, D.A.6
  • 32
    • 76049115164 scopus 로고    scopus 로고
    • The effects of ALV003 pre-digestion of gluten on immune and symptoms in celiac disease in vivo
    • J.A. Tye-Din, R.P. Anderson, R.A. Ffrench, G.J. Brown, P. Hodsman, and M. Siegel The effects of ALV003 pre-digestion of gluten on immune and symptoms in celiac disease in vivo Clin Immunol 134 2010 289 295
    • (2010) Clin Immunol , vol.134 , pp. 289-295
    • Tye-Din, J.A.1    Anderson, R.P.2    Ffrench, R.A.3    Brown, G.J.4    Hodsman, P.5    Siegel, M.6
  • 34
    • 79960254635 scopus 로고    scopus 로고
    • Pharmacological and management strategies for coeliac disease
    • S.C. Donnelly, H.J. Ellis, and P.J. Ciclitira Pharmacological and management strategies for coeliac disease Expert Opin Pharmacother 12 2011 1731 1744
    • (2011) Expert Opin Pharmacother , vol.12 , pp. 1731-1744
    • Donnelly, S.C.1    Ellis, H.J.2    Ciclitira, P.J.3
  • 35
    • 67649160603 scopus 로고    scopus 로고
    • Resistance to celiac disease in humanized HLA-DR3-DQ2-transgenic mice expressing specific anti-gliadin CD4+ T cells
    • A.L. de Kauwe, Z. Chen, R.P. Anderson, C.L. Keech, J.D. Price, and O. Wijburg Resistance to celiac disease in humanized HLA-DR3-DQ2-transgenic mice expressing specific anti-gliadin CD4+ T cells J Immunol 182 2009 7440 7450
    • (2009) J Immunol , vol.182 , pp. 7440-7450
    • De Kauwe, A.L.1    Chen, Z.2    Anderson, R.P.3    Keech, C.L.4    Price, J.D.5    Wijburg, O.6
  • 36
    • 84855280577 scopus 로고    scopus 로고
    • A phase i study to determine safety, tolerability and bioactivity of Nexvax2® in HLA DQ2+ volunteers with celiac disease following a long-term, strict gluten-free diet
    • G.J. Brown, J. Daveson, J.K. Marjason, R.A. Ffrench, D. Smith, and M. Sullivan A phase i study to determine safety, tolerability and bioactivity of Nexvax2® in HLA DQ2+ volunteers with celiac disease following a long-term, strict gluten-free diet Gastroenterology 140 2011 S437 S438
    • (2011) Gastroenterology , vol.140
    • Brown, G.J.1    Daveson, J.2    Marjason, J.K.3    Ffrench, R.A.4    Smith, D.5    Sullivan, M.6
  • 37
    • 77949420644 scopus 로고    scopus 로고
    • The 'hygiene hypothesis' for autoimmune and allergic diseases: An update
    • H. Okada, C. Kuhn, H. Feillet, and J.F. Bach The 'hygiene hypothesis' for autoimmune and allergic diseases: an update Clin Exp Immunol 160 2010 1 9
    • (2010) Clin Exp Immunol , vol.160 , pp. 1-9
    • Okada, H.1    Kuhn, C.2    Feillet, H.3    Bach, J.F.4
  • 38
    • 79952427391 scopus 로고    scopus 로고
    • Effect of hookworm infection on wheat challenge in celiac disease - A randomised double-blinded placebo controlled trial
    • A.J. Daveson, D.M. Jones, S. Gaze, H. McSorley, A. Clouston, and A. Pascoe Effect of hookworm infection on wheat challenge in celiac disease-a randomised double-blinded placebo controlled trial PLoS One 6 2011 e17366
    • (2011) PLoS One , vol.6 , pp. 17366
    • Daveson, A.J.1    Jones, D.M.2    Gaze, S.3    McSorley, H.4    Clouston, A.5    Pascoe, A.6
  • 39
    • 72249085393 scopus 로고    scopus 로고
    • Investigational therapies for celiac disease
    • L. Rodrigo Investigational therapies for celiac disease Expert Opin Investig Drugs 18 2009 1865 1873
    • (2009) Expert Opin Investig Drugs , vol.18 , pp. 1865-1873
    • Rodrigo, L.1
  • 40
    • 79956290534 scopus 로고    scopus 로고
    • Novel therapies for Coeliac Disease
    • L.M. Sollid, and C. Khosla Novel therapies for Coeliac Disease J Intern Med 296 2011 604 613
    • (2011) J Intern Med , vol.296 , pp. 604-613
    • Sollid, L.M.1    Khosla, C.2


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