Induction of high-dose tolerance to the rat anti-mouse IL-6 receptor antibody in NZB/NZW F1 mice

Rheumatology International

Volumn 31, Issue 11, 2011, Pages 1445-1449

  Yoshida, Hiroto ^a   Hashizume, Misato ^a   Suzuki, Miho ^a   Mihara, Masahiko ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Anti IL 6R antibody; Anti rat IgG response; BWF 1 mice; High dose tolerance; Lupus nephritis

Indexed keywords

CD4 ANTIBODY; INTERLEUKIN 6 ANTIBODY; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MR16 1; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; DRUG TOLERANCE; FEMALE; MOUSE; NEPHRITIS; NEW ZEALAND BLACK MOUSE; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; PROTEINURIA;

ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; AUTOIMMUNE DISEASES; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; HETEROZYGOTE; IMMUNE TOLERANCE; IMMUNOGLOBULIN G; INJECTIONS, INTRAVENOUS; INTERLEUKIN-6; MICE; MICE, INBRED NZB; MICE, NUDE; PROTEINURIA; RATS; RECEPTORS, INTERLEUKIN-6;

EID: 83555172669     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-010-1500-8     Document Type: Article

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