Real-time in vivo imaging collagen in lymphedematous skin using multiphoton microscopy

Scanning

Volumn 33, Issue 6, 2011, Pages 463-467

  Wu, Xiufeng ^a   Zhuo, Shuangmu ^b   Chen, Jianxin ^b   Liu, Ningfei ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b FUJIAN NORMAL UNIVERSITY   (China)

Author keywords

Collagen; Image; Lymphedema; Multiphoton microscopy (MPM); Second harmonic generation (SHG)

Indexed keywords

CLINICAL SETTINGS; DERMAL COLLAGEN; IMAGE; IN-VIVO; IN-VIVO IMAGING; LYMPHEDEMA; MONITORING SYSTEM; MORPHOLOGICAL CHANGES; MULTIPHOTON MICROSCOPY; REALTIME IMAGING; SECOND HARMONIC GENERATION (SHG); TWO-PHOTON EXCITED FLUORESCENCE;

HARMONIC GENERATION; NONLINEAR OPTICS; RATS; VISUALIZATION;

COLLAGEN;

COLLAGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; FLUORESCENCE MICROSCOPY; IN VIVO STUDY; LYMPHEDEMA; MALE; MOUSE; MULTIPHOTON MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SKIN EDEMA; TAIL;

ADENOLYMPHOMA; ANIMALS; COLLAGEN; MICE; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; MICROSCOPY, VIDEO; RATS; SKIN NEOPLASMS;

EID: 83555166110     PISSN: 01610457     EISSN: 19328745     Source Type: Journal    
DOI: 10.1002/sca.20266     Document Type: Article

References (25)

1. Becker C, Assouad J, Riquet M, Hidden G,. 2006. Postmastectomy lymphedema: long-term results following microsurgical lymph node transplantation. Ann Surg 243: 313-315. (Pubitemid 43327760)
2. Brown E, McKee T, Tomaso E, Pluen A, Seed B, Boucher Y, Jain RK,. 2003. Dynamic imaging of collagen and its modulation in tumors in vivo using second harmonic generation. Nat Med 9: 796-800. (Pubitemid 36749232)
3. Campagnola PJ, Loew LM,. 2003. Second harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms. Nat Biotechnol 21: 1356-1360. (Pubitemid 37356622)
4. Chen JX, Zhuo SM, Chen R, Xiong S, Zeng H, Jiang X, Chen R, Xie S,. 2007. Depth-resolved spectral imaging of rabbit oesophageal tissue based on two-photon excited fluorescence and second-harmonic generation. New J Phys 9: 212.
5. Cheung L, Han J, Beilhack A, Joshi S, Wilburn P, Dua A, An A, Rockson SG,. 2006. An experimental model for the study of lymphedema and its response to therapeutic lymphangiogenesis. Bio Drugs 20: 363-370. (Pubitemid 46089663)
6. Dunn AK, Wallace VP, Coleno M, Berns MW, Tromberg BJ,. 2000. Influence of optical properties on two-photon fluorescence imaging in turbid samples. Appl Opt 39: 1194-1201.
7. Georgiou E, Theodossiou T, Hovhannisyan V,. 2000. Second and third optical harmonic generation in type I collagen, by nanosecond laser irradiation, over a broad spectral region. Opt Commun 176: 253-260. (Pubitemid 30567858)
8. Jin D, Harada K, Ohnishi S,. 2008. Adrenomedullin induces lymphangiogenesis and ameliorates secondary lymphoedema. Cardiovasc Res 80: 339-345.
9. Jin da P, An A, Liu J, Nakamura K, Rockson SG,. 2009. Therapeutic responses to exogenous VEGF-C administration in experimental lymphedema: immunohistochemical and molecular characterization. Lymphat Res Biol 7: 47-57.
10. Koehler MJ, König K, Elsner P,. 2006. In vivo assessment of human skin aging by multiphoton laser scanning tomography. Opt Lett 19: 2879-2881. (Pubitemid 44600100)
11. Koenig K, Riemann I,. 2003. High-resolution multiphoton tomography of human skin with subcellular spatial resolution and picosecond time resolution. J Biomed Opt 8: 432-439.
12. Laiho LH, Plete S, Hancewicz TM, Kaplan PD, So PT,. 2005. Two-photon 3-D mapping of ex vivo human skin endogenous fluorescence species based on fluorescence emission spectra. J Biomed Opt 10:024016.
13. Levene MJ, Dombeck DA, Kasischke KA, Molloy RP, Webb WW,. 2004. In vivo multiphoton microscopy of deep brain tissue. J Neurophysiol 91: 1908-1912. (Pubitemid 38339356)
14. Lin SJ, Wu RJ, Tan HY, Lo W, Lin WC, Young TH, Hsu CJ, Chen JS, Jee SH, Dong CY,. 2005. Evaluating cutaneous photoaging by use of multiphoton fluorescence and second-harmonic generation microscopy. Opt Lett 17: 2275-2277. (Pubitemid 41345869)
15. Nakamura K, Radhakrishnan K, Wong YM,. 2009. Anti-inflammatory pharmacotherapy with ketoprofen ameliorates experimental lymphatic vascular insufficiency in mice. PLoS One 12, e8380.
16. Rockson SG,. 2001. Lymphedema. Am J Med 110: 288-295. (Pubitemid 32187290)
17. Rutkowski JM, Markhus CE, Gyenge CC, Alitalo K, Wiig H, Swartz MA,. 2010. Dermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema. Am J Pathol 176: 1122-1129.
18. Stanley GR,. 2009. The unique biology of lymphatic edema. Lymphat Res Biol 2: 97-100.
19. Stracke F, Weiss B, Lehr C, König K, Schaefer UF, Schneider M,. 2006. SchneiderMMultiphoton microscopy for the investigation of dermal penetration of nanoparticle-borne drugs. J Invest Dermatol 126: 2224-2233. (Pubitemid 44413169)
20. Tassenoy A, De Mey J, Stadnik T,. 2009. Histological findings compared with magnetic resonance and ultrasonographic imaging in irreversible postmastectomy lymphedema: a case study. Lymphat Res Biol 3: 145-151.
21. Zhuo SM, Chen JX, Luo TS,. 2006. Multimode nonlinear optical imaging of the dermis in ex vivo human skin based on the combination of multichannel mode and Lambda mode. Opt Express 14: 7810-7820.
22. Zhuo SM, Chen JX, Jiang XS, Xie S, Chen R, Cao N, Zou Q, Xiong S,. 2007a. The layered-resolved microstructure and spectrosocpy of mouse oral mucosa using multiphoton microscopy. Phys Med Biol 52: 4967-4980. (Pubitemid 47232299)
23. Zhuo SM, Chen JX, Jiang XS, Cheng X, Xie S,. 2007b. Visualizing extracellular matrix and sensing fibroblasts metabolism in human dermis by nonlinear spectral imaging. Skin Res Technol 13: 406-411. (Pubitemid 47506404)
24. Zipfel WR, Williams RM, Webb WW,. 2003. Nonlinear magic: multiphoton microscopy in the biosciences. Nat Biotechnol 21: 1369-1377. (Pubitemid 37356624)
25. Zoumi A, Yeh A, Tromberg BJ,. 2002. Imaging cells and extracellular matrix in vivo by using second-harmonic generation and two-photon excited fluorescence. Proc Natl Acad Sci USA 99: 11014-11019. (Pubitemid 34920871)