Endogenous nitric oxide formation correlates negatively with circulating matrix metalloproteinase (MMP)-2 and MMP-9 levels in black subjects

Molecular and Cellular Biochemistry

Volumn 360, Issue 1-2, 2012, Pages 393-399

  Metzger, Ingrid F ^a   Sandrim, Valéria C ^b   Tanus Santos, Jose E ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Santa Casa de Belo Horizonte   (Brazil)

Author keywords

Matrix metalloproteinases; Nitric oxide; Nitrites; Zymography

Indexed keywords

GELATINASE A; GELATINASE B; NITRIC OXIDE; NITRITE;

ADULT; ARTICLE; BLOOD SAMPLING; CHEMOLUMINESCENCE; CORRELATION ANALYSIS; HUMAN; HUMAN TISSUE; MALE; NEGRO; NORMAL HUMAN; PROTEIN BLOOD LEVEL; ZYMOGRAPHY;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; BIOLOGICAL MARKERS; BRAZIL; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NITRIC OXIDE; NITRITES; STATISTICS, NONPARAMETRIC; YOUNG ADULT;

EID: 83555163931     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-1079-8     Document Type: Article

References (51)

1. S Moncada EA Higgs 1991 Endogenous nitric oxide: physiology, pathology and clinical relevance Eur J Clin Invest 21 4 361 374 1718757 10.1111/j.1365-2362.1991.tb01383.x 1:CAS:528:DyaK3MXmsFams7k%3D
2. MM Castro E Rizzi L Figueiredo-Lopes K Fernandes LM Bendhack DL Pitol RF Gerlach JE Tanus-Santos 2008 Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats Atherosclerosis 198 2 320 331 18054360 10.1016/j. atherosclerosis.2007.10.011 1:CAS:528:DC%2BD1cXmtlSqsb4%3D (Pubitemid 351707391)
3. MM Castro E Rizzi CM Prado MA Rossi JE Tanus-Santos RF Gerlach 2010 Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling Matrix Biol 29 3 194 201 19969080 10.1016/j.matbio.2009.11.005 1:CAS:528:DC%2BC3cXksVakur0%3D
4. R Lacchini AL Jacob-Ferreira MR Luizon FB Coeli TC Izidoro-Toledo S Gasparini MC Ferreira-Sae R Schreiber W Nadruz Jr JE Tanus-Santos 2010 Matrix metalloproteinase 9 gene haplotypes affect left ventricular hypertrophy in hypertensive patients Clin Chim Acta 411 1940 1944 20707992 10.1016/j.cca.2010. 08.008 1:CAS:528:DC%2BC3cXht1OgsLnP
5. E Rizzi MM Castro CM Prado CA Silva R Fazan Jr MA Rossi JE Tanus-Santos RF Gerlach 2010 Matrix metalloproteinase inhibition improves cardiac dysfunction and remodeling in 2-kidney, 1-clip hypertension J Card Fail 16 7 599 608 20610236 10.1016/j.cardfail.2010.02.005 1:CAS:528:DC%2BC3cXotVWis7c%3D
6. VA Belo DC Souza-Costa CM Lana FL Caputo AM Marcaccini RF Gerlach MG Bastos JE Tanus-Santos 2009 Assessment of matrix metalloproteinase (MMP)-2, MMP-8, MMP-9, and their inhibitors, the tissue inhibitors of metalloproteinase (TIMP)-1 and TIMP-2 in obese children and adolescents Clin Biochem 42 10-11 984 990 19358835 10.1016/j.clinbiochem.2009.03.025 1:CAS:528:DC%2BD1MXnt1emt7k%3D
7. FM Goncalves AL Jacob-Ferreira VA Gomes A Casella-Filho AC Chagas AM Marcaccini RF Gerlach JE Tanus-Santos 2009 Increased circulating levels of matrix metalloproteinase (MMP)-8, MMP-9, and pro-inflammatory markers in patients with metabolic syndrome Clin Chim Acta 403 1-2 173 177 19254704 10.1016/j.cca.2009.02.013 1:CAS:528:DC%2BD1MXltFWms7k%3D
8. ML Martinez E Rizzi MM Castro K Fernandes LM Bendhack RF Gerlach JE Tanus-Santos 2008 Lercanidipine decreases vascular matrix metalloproteinase-2 activity and protects against vascular dysfunction in diabetic rats Eur J Pharmacol 599 1-3 110 116 18930722 10.1016/j.ejphar.2008.10.007 1:CAS:528:DC%2BD1cXhtlaqur3M
9. V Fontana PS Silva VA Belo RC Antonio CS Ceron C Biagi RF Gerlach JE Tanus-Santos 2011 Consistent alterations of circulating matrix metalloproteinases levels in untreated hypertensives and in spontaneously hypertensive rats: a relevant pharmacological target Basic Clin Pharmacol Toxicol 109 2 130 137 21401887 10.1111/j.1742-7843.2011.00698.x 1:CAS:528:DC%2BC3MXpvVSjsr4%3D
10. C Demacq IF Metzger RF Gerlach JE Tanus-Santos 2008 Inverse relationship between markers of nitric oxide formation and plasma matrix metalloproteinase-9 levels in healthy volunteers Clin Chim Acta 394 1-2 72 76 18455513 10.1016/j.cca.2008.04.008 1:CAS:528:DC%2BD1cXmvFems7Y%3D
11. MJ Eagleton DA Peterson VV Sullivan KJ Roelofs JA Ford JC Stanley GR Upchurch Jr 2002 Nitric oxide inhibition increases aortic wall matrix metalloproteinase-9 expression J Surg Res 104 1 15 21 11971672 10.1006/jsre.2002.6396 1:CAS:528:DC%2BD38XjtVKksb0%3D (Pubitemid 34948327)
12. GR Upchurch Jr JW Ford SJ Weiss BS Knipp DA Peterson RW Thompson MJ Eagleton AJ Broady MC Proctor JC Stanley 2001 Nitric oxide inhibition increases matrix metalloproteinase-9 expression by rat aortic smooth muscle cells in vitro J Vasc Surg 34 1 76 83 11436078 10.1067/mva.2001.115598 (Pubitemid 33660693)
13. MV Gurjar J DeLeon RV Sharma RC Bhalla 2001 Mechanism of inhibition of matrix metalloproteinase-9 induction by NO in vascular smooth muscle cells J Appl Physiol 91 3 1380 1386 11509539 1:CAS:528:DC%2BD3MXmvV2qt7k%3D (Pubitemid 32803936)
14. MT Gladwin NJ Raat S Shiva C Dezfulian N Hogg DB Kim-Shapiro RP Patel 2006 Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation Am J Physiol Heart Circ Physiol 291 5 H2026 H2035 16798825 10.1152/ajpheart.00407.2006 1:CAS:528:DC%2BD28Xht1GnsLjP
15. MT Gladwin JH Crawford RP Patel 2004 The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation Free Radic Biol Med 36 6 707 717 14990351 10.1016/j.freeradbiomed.2003.11.032 1:CAS:528: DC%2BD2cXhsFWkurg%3D (Pubitemid 38264415)
16. A Webb R Bond P McLean R Uppal N Benjamin A Ahluwalia 2004 Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage Proc Natl Acad Sci USA 101 37 13683 13688 15347817 10.1073/pnas.0402927101 1:CAS:528:DC%2BD2cXnvFehsL0%3D (Pubitemid 39238463)
17. P Kleinbongard A Dejam T Lauer T Jax S Kerber P Gharini J Balzer RB Zotz RE Scharf R Willers AN Schechter M Feelisch M Kelm 2006 Plasma nitrite concentrations reflect the degree of endothelial dysfunction in humans Free Radic Biol Med 40 2 295 302 16413411 10.1016/j.freeradbiomed.2005.08.025 1:CAS:528:DC%2BD28XksVehtQ%3D%3D (Pubitemid 43069353)
18. IF Metzger JT Sertorio JE Tanus-Santos 2006 Relationship between systemic nitric oxide metabolites and cyclic GMP in healthy male volunteers Acta Physiol (Oxf) 188 2 123 127 10.1111/j.1748-1716.2006.01612.x 1:CAS:528: DC%2BD28XhtVCnsr3N (Pubitemid 44337809)
19. C Murphy GS Kanaganayagam B Jiang PJ Chowienczyk R Zbinden M Saha S Rahman AM Shah MS Marber MT Kearney 2007 Vascular dysfunction and reduced circulating endothelial progenitor cells in young healthy UK South Asian men Arterioscler Thromb Vasc Biol 27 4 936 942 17255539 10.1161/01.ATV.0000258788. 11372.d0 1:CAS:528:DC%2BD2sXislCrsrw%3D (Pubitemid 46606728)
20. DA Rosenbaum M Pretorius JV Gainer D Byrne LJ Murphey CA Painter DE Vaughan NJ Brown 2002 Ethnicity affects vasodilation, but not endothelial tissue plasminogen activator release, in response to bradykinin Arterioscler Thromb Vasc Biol 22 6 1023 1028 12067915 10.1161/01.ATV.0000017704.45007.1D 1:CAS:528:DC%2BD38XkvFOktrw%3D (Pubitemid 34655234)
21. CP Fenster VM Darley-Usmar AL Landar BA Gower RL Weinsier GR Hunter RP Patel 2004 Weight loss and race modulate nitric oxide metabolism in overweight women Free Radic Biol Med 37 5 695 702 15288126 10.1016/j.freeradbiomed.2004.05. 021 1:CAS:528:DC%2BD2cXmt1Klsrc%3D (Pubitemid 38993515)
22. RW Ke D Todd Pace RA Ahokas 2003 Effect of short-term hormone therapy on oxidative stress and endothelial function in African American and Caucasian postmenopausal women Fertil Steril 79 5 1118 1122 12738505 10.1016/S0015- 0282(03)00153-5 (Pubitemid 36547848)
23. CM Stein CC Lang R Nelson M Brown AJ Wood 1997 Vasodilation in black Americans: attenuated nitric oxide-mediated responses Clin Pharmacol Ther 62 4 436 443 9357395 10.1016/S0009-9236(97)90122-3 1:CAS:528:DyaK2sXntlegs7o%3D (Pubitemid 27475228)
24. P Sareli IV Radevski ZP Valtchanova E Libhaber GP Candy E Den Hond C Libhaber D Skudicky JG Wang JA Staessen 2001 Efficacy of different drug classes used to initiate antihypertensive treatment in black subjects: results of a randomized trial in Johannesburg, South Africa Arch Intern Med 161 7 965 971 11295959 10.1001/archinte.161.7.965 1:CAS:528:DC%2BD3MXjtFWhtL0%3D (Pubitemid 32295650)
25. L Kalinowski IT Dobrucki T Malinski 2004 Race-specific differences in endothelial function: predisposition of African Americans to vascular diseases Circulation 109 21 2511 2517 15159296 10.1161/01.CIR.0000129087.81352.7A (Pubitemid 38720549)
26. J Fielitz M Leuschner HR Zurbrugg B Hannack R Pregla R Hetzer V Regitz-Zagrosek 2004 Regulation of matrix metalloproteinases and their inhibitors in the left ventricular myocardium of patients with aortic stenosis J Mol Med 82 12 809 820 15558223 10.1007/s00109-004-0606-4 1:CAS:528: DC%2BD2cXhtVOqsL3I
27. AS Marroni IF Metzger DC Souza-Costa S Nagassaki VC Sandrim RX Correa F Rios-Santos JE Tanus-Santos 2005 Consistent interethnic differences in the distribution of clinically relevant endothelial nitric oxide synthase genetic polymorphisms Nitric Oxide 12 3 177 182 15797845 10.1016/j.niox.2005.02.002 1:CAS:528:DC%2BD2MXivVejtrk%3D (Pubitemid 40432137)
28. JE Tanus-Santos M Desai DA Flockhart 2001 Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants Pharmacogenetics 11 8 719 725 11692081 10.1097/00008571-200111000-00011 1:CAS:528:DC%2BD38XnsFKru78%3D (Pubitemid 33078242)
29. R Lacchini IF Metzger M Luizon M Ishizawa JE Tanus-Santos 2010 Interethnic differences in the distribution of matrix metalloproteinases genetic polymorphisms are consistent with interethnic differences in disease prevalence DNA Cell Biol 29 11 649 655 20590473 10.1089/dna.2010.1056 1:CAS:528: DC%2BC3cXhtlaksr%2FO
30. K Bibbins-Domingo MJ Pletcher F Lin E Vittinghoff JM Gardin A Arynchyn CE Lewis OD Williams SB Hulley 2009 Racial differences in incident heart failure among young adults N Engl J Med 360 12 1179 1190 19297571 10.1056/NEJMoa0807265 1:CAS:528:DC%2BD1MXjtlersbg%3D
31. H Bahrami R Kronmal DA Bluemke J Olson S Shea K Liu GL Burke JA Lima 2008 Differences in the incidence of congestive heart failure by ethnicity: the multi-ethnic study of atherosclerosis Arch Intern Med 168 19 2138 2145 18955644 10.1001/archinte.168.19.2138
32. GA Mensah AH Mokdad ES Ford KJ Greenlund JB Croft 2005 State of disparities in cardiovascular health in the United States Circulation 111 10 1233 1241 15769763 10.1161/01.CIR.0000158136.76824.04 (Pubitemid 40389086)
33. A Hozawa AR Folsom AR Sharrett LE Chambless 2007 Absolute and attributable risks of cardiovascular disease incidence in relation to optimal and borderline risk factors: comparison of African American with white subjects-Atherosclerosis Risk in Communities Study Arch Intern Med 167 6 573 579 17389288 10.1001/archinte.167.6.573 (Pubitemid 46513226)
34. JF Carroll KG Fulda AL Chiapa M Rodriquez DR Phelps KM Cardarelli JK Vishwanatha R Cardarelli 2009 Impact of race/ethnicity on the relationship between visceral fat and inflammatory biomarkers Obesity (Silver Spring) 17 7 1420 1427 1:CAS:528:DC%2BD1MXnslGrt7o%3D
35. S Nagassaki JT Sertorio IF Metzger AF Bem JB Rocha JE Tanus-Santos 2006 eNOS gene T-786C polymorphism modulates atorvastatin-induced increase in blood nitrite Free Radic Biol Med 41 7 1044 1049 16962929 10.1016/j.freeradbiomed. 2006.04.026 1:CAS:528:DC%2BD28XpsVOiu74%3D (Pubitemid 44331568)
36. C Demacq VB Vasconcellos AM Marcaccini RF Gerlach WA Silva JE Tanus-Santos 2008 Functional polymorphisms in the promoter of the matrix metalloproteinase-9 (MMP-9) gene are not linked with significant plasma MMP-9 variations in healthy subjects Clin Chem Lab Med 46 1 57 63 18194081 10.1515/CCLM.2008.014 1:CAS:528:DC%2BD1cXitVWjtbk%3D
37. RF Gerlach C Demacq K Jung JE Tanus-Santos 2007 Rapid separation of serum does not avoid artificially higher matrix metalloproteinase (MMP)-9 levels in serum versus plasma Clin Biochem 40 1-2 119 123 17150202 10.1016/j.clinbiochem. 2006.10.007 1:CAS:528:DC%2BD2sXhsFKjsg%3D%3D (Pubitemid 46014168)
38. S Akool el H Kleinert FM Hamada MH Abdelwahab U Forstermann J Pfeilschifter W Eberhardt 2003 Nitric oxide increases the decay of matrix metalloproteinase 9 mRNA by inhibiting the expression of mRNA-stabilizing factor HuR Mol Cell Biol 23 14 4901 4916 10.1128/MCB.23.14.4901-4916.2003 (Pubitemid 36793336)
39. W Eberhardt T Beeg KF Beck S Walpen S Gauer H Bohles J Pfeilschifter 2000 Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells Kidney Int 57 1 59 69 10620188 10.1046/j.1523-1755.2000.00808.x 1:CAS:528:DC%2BD3cXivFOlur8%3D (Pubitemid 30227754)
40. MF Montenegro JH Amaral LC Pinheiro EK Sakamoto GC Ferreira RI Reis DM Marcal RP Pereira JE Tanus-Santos 2011 Sodium nitrite downregulates vascular NADPH oxidase and exerts antihypertensive effects in hypertension Free Radic Biol Med 51 1 144 152 21530643 10.1016/j.freeradbiomed.2011.04.005 1:CAS:528:DC%2BC3MXntFSktLY%3D
41. CA Dias-Junior SB Cau AM Oliveira MM Castro MF Montenegro RF Gerlach JE Tanus-Santos 2009 Nitrite or sildenafil, but not BAY 41-2272, blunt acute pulmonary embolism-induced increases in circulating matrix metalloproteinase-9 and oxidative stress Thromb Res 124 3 349 355 19150571 10.1016/j.thromres.2008. 12.006 1:CAS:528:DC%2BD1MXosVynsb8%3D
42. CA Dias-Junior MT Gladwin JE Tanus-Santos 2006 Low-dose intravenous nitrite improves hemodynamics in a canine model of acute pulmonary thromboembolism Free Radic Biol Med 41 12 1764 1770 17157179 10.1016/j.freeradbiomed.2006.08.022 1:CAS:528:DC%2BD28XhtlShs7zI (Pubitemid 44848399)
43. Metzger IF, Ishizawa MH, Rios-Santos F, Carvalho WA, Tanus-Santos JE (2011) Endothelial nitric oxide synthase gene haplotypes affect nitrite levels in black subjects. Pharmacogenomics J. doi: 10.1038/tpj.2010.52
44. A Dejam CJ Hunter MM Pelletier LL Hsu RF Machado S Shiva GG Power M Kelm MT Gladwin AN Schechter 2005 Erythrocytes are the major intravascular storage sites of nitrite in human blood Blood 106 2 734 739 15774613 10.1182/blood-2005-02-0567 1:CAS:528:DC%2BD2MXmtleqtLs%3D (Pubitemid 40981274)
45. ES Kehmeier M Kropp P Kleinbongard T Lauer J Balzer MW Merx G Heusch M Kelm W Lepper T Rassaf 2008 Serial measurements of whole blood nitrite in an intensive care setting Free Radic Biol Med 44 11 1945 1950 18374662 10.1016/j.freeradbiomed.2008.02.014 1:CAS:528:DC%2BD1cXlslOqsr8%3D
46. DC Souza-Costa L Figueiredo-Lopes JC Alves-Filho MC Semprini RF Gerlach FQ Cunha JE Tanus-Santos 2007 Protective effects of atorvastatin in rat models of acute pulmonary embolism: involvement of matrix metalloproteinase-9 Crit Care Med 35 1 239 245 17133179 10.1097/01.CCM.0000251638.67104.C3 1:CAS:528:DC%2BD2sXjtVaq (Pubitemid 46035701)
47. DC Souza-Costa VC Sandrim LF Lopes RF Gerlach EM Rego JE Tanus-Santos 2007 Anti-inflammatory effects of atorvastatin: modulation by the T-786C polymorphism in the endothelial nitric oxide synthase gene Atherosclerosis 193 2 438 444 16938300 10.1016/j.atherosclerosis.2006.07.020 1:CAS:528: DC%2BD2sXotVCltr4%3D (Pubitemid 47058109)
48. F Barbosa Jr JT Sertorio RF Gerlach JE Tanus-Santos 2006 Clinical evidence for lead-induced inhibition of nitric oxide formation Arch Toxicol 80 12 811 816 16670857 10.1007/s00204-006-0111-3 1:CAS:528:DC%2BD28Xht1enu7bM (Pubitemid 44833077)
49. KC de Marco CJ Passos J Sertorio JE Tanus-Santos F Barbosa Jr 2010 Environmental exposure to methylmercury is associated with a decrease in nitric oxide production Basic Clin Pharmacol Toxicol 106 5 411 415 20050842
50. F Barbosa Jr RF Gerlach JE Tanus-Santos 2006 Matrix metalloproteinase-9 activity in plasma correlates with plasma and whole blood lead concentrations Basic Clin Pharmacol Toxicol 98 6 559 564 16700817 10.1111/j.1742-7843.2006.pto- 392.x 1:CAS:528:DC%2BD28Xls1Sitbo%3D
51. Jacob-Ferreira AL, Passos CJ, Jordao AA, Fillion M, Mergler D, Lemire M, Gerlach RF, Barbosa Jr F, Tanus-Santos JE (2009) Mercury Exposure Increases Circulating Net Matrix Metalloproteinase (MMP)-2 and MMP-9 Activities. Basic Clin Pharmacol Toxicol 105:281-288