Prevalence of clinically relevant oral mucositis in outpatients receiving myelosuppressive chemotherapy for solid tumors

Supportive Care in Cancer

Volumn 20, Issue 1, 2012, Pages 175-183

  Wuketich, Stefan ^a   Hienz, Stefan A ^b   Marosi, Christine ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Chemotherapy; Mucositis; Oral health; Prevalence; Risk factors; Solid tumors

Indexed keywords

ANTINEOPLASTIC AGENT;

ADULT; AGED; ARTICLE; BONE MARROW SUPPRESSION; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CLINICAL FEATURE; COLORECTAL CANCER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; DIGESTIVE SYSTEM CANCER; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG SAFETY; EATING DISORDER; ERYTHEMA; ERYTHROCYTE COUNT; FEMALE; GINGIVA DISEASE; HEAD AND NECK CANCER; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MESOTHELIOMA; MOUTH HYGIENE; MOUTH PLAQUE; OUTPATIENT CARE; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RARE DISEASE; RISK FACTOR; SMOKING HABIT; SOLID TUMOR; STOMATITIS; UROGENITAL TRACT CANCER;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; ORAL HEALTH; ORAL HYGIENE; PREVALENCE; PROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SEX FACTORS; SMOKING; STOMATITIS; YOUNG ADULT;

EID: 83555160849     PISSN: 09414355     EISSN: 14337339     Source Type: Journal    
DOI: 10.1007/s00520-011-1107-y     Document Type: Article

References (36)

1. American Academy of Periodontology (1997) Periodontal considerations in the management of the cancer patient. Committee on Research, Science and Therapy of the American Academy of Periodontology. J Periodontol 68(8):791-801
2. Barasch A, Peterson DE (2003) Risk factors for ulcerative oral mucositis in cancer patients: unanswered questions. Oral Oncol 39 (2):91-100 (Pubitemid 36050914)
3. Cella D, Pulliam J, Fuchs H, Miller C, Hurd D, Wingard JR, Sonis ST, Martin PJ, Giles F (2003) Evaluation of pain associated with oral mucositis during the acute period after administration of high-dose chemotherapy. Cancer 98(2):406-412 (Pubitemid 36828468)
4. Chansky K, Benedetti J, Macdonald JS (2005) Differences in toxicity between men and women treated with 5-fluorouracil therapy for colorectal carcinoma. Cancer 103(6):1165-1171 (Pubitemid 40328086)
5. Dodd MJ, Miaskowski C, Shiba GH, Dibble SL, Greenspan D, MacPhail L, Paul SM, Larson P (1999) Risk factors for chemotherapy-induced oral mucositis: dental appliances, oral hygiene, previous oral lesions, and history of smoking. Cancer Investig 17(4):278-284 (Pubitemid 29202938)
6. Elting LS, Cooksley C, Chambers M, Cantor SB, Manzullo E, Rubenstein EB (2003) The burdens of cancer therapy. Clinical and economic outcomes of chemotherapy-induced mucositis. Cancer 98(7):1531-1539 (Pubitemid 37151510)
7. Elting LS, Cooksley CD, Chambers MS, Garden AS (2007) Risk, outcomes, and costs of radiation-induced oral mucositis among patients with head-and-neck malignancies. Int J Radiat Oncol Biol Phys 68(4):1110-1120 (Pubitemid 47048578)
8. Elting LS, Keefe DM, Sonis ST, Garden AS, Spijkervet FK, Barasch A, Tishler RB, Canty TP, Kudrimoti MK, Vera-Llonch M (2008) Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy: demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life. Cancer 113 (10):2704-2713
9. Gallagher JG (1995) Mucositis. In: Klastersky J, Schimpff SC, Senn H-J (eds) Handbook of supportive care in cancer. Marcel Dekker, Inc., New York, pp 147-156
10. Goldberg SL, Chiang L, Selina N, Hamarman S (2004) Patient perceptions about chemotherapy-induced oral mucositis: implications for primary/secondary prophylaxis strategies. Support Care Cancer 12(7):526-530 (Pubitemid 38931686)
11. Hsiao G, Sonis S (2003) Oral mucositis. In: Max M, Lynn J (eds) Interactive textbook on clinical symptom research. National Institute of Dental and Craniofacial Research. http://symptomresearch.nih.gov/Chapter-17/index.htm. Accessed 29 Sept. 2010
12. Jones JA, Avritscher EB, Cooksley CD, Michelet M, Bekele BN, Elting LS (2006) Epidemiology of treatment-associated mucosal injury after treatment with newer regimens for lymphoma, breast, lung, or colorectal cancer. Support Care Cancer 14(6):505-515
13. Keefe DM, Schubert MM, Elting LS, Sonis ST, Epstein JB, Raber-Durlacher JE, Migliorati CA, McGuire DB, Hutchins RD, Peterson DE (2007) Updated clinical practice guidelines for the prevention and treatment of mucositis. Cancer 109(5):820-831 (Pubitemid 46335677)
14. Kostler WJ, Hejna M, Wenzel C, Zielinski CC (2001) Oral mucositis complicating chemotherapy and/or radiotherapy: options for prevention and treatment. CA Cancer J Clin 51 (5):290-315 (Pubitemid 34232774)
15. Lang WP, Farghaly MM, Ronis DL (1994) The relation of preventive dental behaviors to periodontal health status. J Clin Periodontol 21(3):194-198
16. Lerner L, Weiner D, Katz R, Reznick AZ, Pollack S (2009) Increased pro-inflammatory activity and impairment of human monocyte differentiation induced by in vitro exposure to cigarette smoke. J Physiol Pharmacol 60(Suppl 5):81-86
17. Loe H, Silness J (1963) Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 21:533-551
18. McCarthy GM, Awde JD, Ghandi H, Vincent M, Kocha WI (1998) Risk factors associated with mucositis in cancer patients receiving 5-fluorouracil. Oral Oncol 34(6):484-490 (Pubitemid 28546862)
19. McCollum AD, Catalano PJ, Haller DG, Mayer RJ, Macdonald JS, Benson AB 3rd, Fuchs CS (2002) Outcomes and toxicity in African-American and Caucasian patients in a randomized adjuvant chemotherapy trial for colon cancer. J Natl Cancer Inst 94(15):1160-1167 (Pubitemid 34919053)
20. McGuire DB, Correa ME, Johnson J, Wienandts P (2006) The role of basic oral care and good clinical practice principles in the management of oral mucositis. Support Care Cancer 14(6):541-547
21. National Cancer Institute (2008) Oral complications of chemotherapy and head/neck radiation (PDQ®): Health Professional Version. http://www.cancer.gov/cancertopics/pdq/supportivecare/oralcomplications/ HealthProfessional/page1. Accessed 5 May 2008
22. Overholser CD, Peterson DE, Williams LT, Schimpff SC (1982) Periodontal infection in patients with acute nonlymphocyte leukemia. Prevalence of acute exacerbations. Arch Intern Med 142(3):551-554 (Pubitemid 12190746)
23. Overholser CDJ (1995) Oral care for the cancer patient. In: Klastersky J, Schimpff SC, Senn H-J (eds) Handbook of supportive care in cancer. Marcel Dekker, Inc., New York, pp 125-145
24. Peterson DE, Minah GE, Overholser CD, Suzuki JB, DePaola LG, Stansbury DM, Williams LT, Schimpff SC (1987) Microbiology of acute periodontal infection in myelosuppressed cancer patients. J Clin Oncol 5(9):1461-1468
25. Raber-Durlacher JE, Weijl NI, Abu Saris M, de Koning B, Zwinderman AH, Osanto S (2000) Oral mucositis in patients treated with chemotherapy for solid tumors: a retrospective analysis of 150 cases. Support Care Cancer 8(5):366-371 (Pubitemid 30650520)
26. Robien K, Schubert MM, Bruemmer B, Lloid ME, Potter JD, Ulrich CM (2004) Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukemia. J Clin Oncol 22(7):1268-1275 (Pubitemid 41079841)
27. Ronis DL, Lang WP, Farghaly MM, Passow E (1993) Tooth brushing, flossing, and preventive dental visits by Detroit-area residents in relation to demographic and socioeconomic factors. J Public Health Dent 53(3):138-145
28. Silness J, Loe H (1964) Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 22:121-135
29. Sonis ST, Eilers JP, Epstein JB, LeVeque FG, Liggett WH Jr, Mulagha MT, Peterson DE, Rose AH, Schubert MM, Spijkervet FK, Wittes JP (1999) Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy. Mucositis study group. Cancer 85 (10):2103-2113 (Pubitemid 29215547)
30. Sonis ST (2004) A biological approach to mucositis. J Support Oncol 2(1):21-32, discussion 35-26 (Pubitemid 39430224)
31. Sonis ST, Elting LS, Keefe D, Peterson DE, Schubert M, Hauer-Jensen M, Bekele BN, Raber-Durlacher J, Donnelly JP, Rubenstein EB (2004) Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients. Cancer 100(9 Suppl):1995-2025 (Pubitemid 38528741)
32. Trotti A, Bellm LA, Epstein JB, Frame D, Fuchs HJ, Gwede CK, Komaroff E, Nalysnyk L, Zilberberg MD (2003) Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review. Radiother Oncol 66 (3):253-262 (Pubitemid 36556043)
33. Vokurka S, Bystricka E, Koza V, Scudlova J, Pavlicova V, Valentova D, Visokaiova M, Misaniova L (2006) Higher incidence of chemotherapy induced oral mucositis in females: a supplement of multivariate analysis to a randomized multicentre study. Support Care Cancer 14(9):974-976
34. Woolfolk MW, Lang WP, Borgnakke WS, Taylor GW, Ronis DL, Nyquist LV (1999) Determining dental checkup frequency. J Am Dent Assoc 130(5):715-723
35. World Health Organization (1997) Oral health surveys: basic methods, 4th edn. World Health Organization, Geneva, Switzerland
36. Zalcberg J, Kerr D, Seymour L, Palmer M (1998) Haematological and non-haematological toxicity after 5-fluorouracil and leucovorin in patients with advanced colorectal cancer is significantly associated with gender, increasing age and cycle number. Tomudex International Study Group. Eur J Cancer 34(12):1871-1875 (Pubitemid 28535434)