Cancer: A drug-resistant duo

Nature

Volumn 480, Issue 7377, 2011, Pages 329-330

  Lavoie, Hugo ^a   Therrien, Marc ^a  

^a INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; RAS PROTEIN; VEMURAFENIB;

CANCER; CHEMOTHERAPY; DRUG; DRUG RESISTANCE;

CELL PROLIFERATION; CELL SURVIVAL; DIMERIZATION; DRUG RESISTANCE; GAIN OF FUNCTION MUTATION; HUMAN; MELANOMA; METASTASIS; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; TUMOR CELL; TUMOR REGRESSION;

ALTERNATIVE SPLICING; ANIMALS; DRUG RESISTANCE, NEOPLASM; HUMANS; PROTEIN MULTIMERIZATION; PROTO-ONCOGENE PROTEINS B-RAF;

EID: 83455259711     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/480329a     Document Type: Short Survey

References (15)

1. Bollag, G. et al. Nature 467, 596-599 (2010).
2. Chapman, P. B. et al. N. Engl. J. Med. 364, 2507-2516 (2011).
3. Flaherty, K. T. et al. N. Engl. J. Med. 363, 809-819 (2010).
4. Poulikakos, P. I. et al. Nature 480, 387-390 (2011).
5. Gray-Schopfer, V., Wellbrock, C. & Marais, R. Nature 445, 851-857 (2007).
6. Wellbrock, C., Karasarides, M. & Marais, R. Nature Rev. Mol. Cell Biol. 5, 875-885 (2004).
7. Udell, C. M., Rajakulendran, T., Sicheri, F. & Therrien, M. Cell. Mol. Life Sci. 68, 553-565 (2011).
8. Wagle, N. et al. J. Clin. Oncol. 29, 3085-3096 (2011).
9. Johannessen, C. M. et al. Nature 468, 968-972 (2010).
10. Nazarian, R. et al. Nature 468, 973-977 (2010).
11. Kobayashi, S. et al. N. Engl. J. Med. 352, 786-792 (2005).
12. Nardi, V., Azam, M. & Daley, G. Q. Curr. Opin. Hematol. 11, 35-43 (2004).
13. Poulikakos, P. I., Zhang, C., Bollag, G., Shokat, K. M. & Rosen, N. Nature 464, 427-430 (2010).
14. Heidorn, S. J. et al. Cell 140, 209-221 (2010).
15. Hatzivassiliou, G. et al. Nature 464, 431-435 (2010).