In vitro antibacterial activity of some antihistaminics belonging to different groups against multi-drug resistant clinical isolates

Brazilian Journal of Microbiology

Volumn 42, Issue 3, 2011, Pages 980-991

  El Nakeeb, Moustafa A ^a   Abou Shleib, Hamida M ^a   Khalil, Amal M ^a   Omar, Hoda G ^a   El Halfawy, Omar M ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Antihistaminics; Bactericidal activity; Bacteriostatic activity; Gram negative isolates; Grampositive isolates

Indexed keywords

EID: 83455258640     PISSN: 15178382     EISSN: 16784405     Source Type: Journal    
DOI: 10.1590/S1517-83822011000300018     Document Type: Article

References (37)

1. Abernathy, C.O., Lukacs, L., Zimmerman, H.J. (1975). Toxicity of tricyclic antidepressants to isolated rat hepatocytes. Biochem Pharmacol 24(3), 347-50.
2. Ahmed, M., Hadgraft, J., Burton, J.S., Kellaway, I.W. (1980). The interaction of mequitazine with phospholipid model membranes. Chem Phys Lipids 27(3), 251-62.
3. Andrews, J.M. (2001). Determination of minimum inhibitory concentrations. J Antimicrob Chemother 48 Suppl 1, 5-16.
4. Andrews, J.M. (2007). BSAC standardized disc susceptibility testing method (version 6). J Antimicrob Chemother 60(1), 20-41.
5. Attwood, D., Udeala, O.K. (1974). Aggregation of antihistamines in aqueous solution: micellar properties of some diphenylmethane derivatives. J Pharm Pharmacol 26(11), 854-60.
6. Attwood, D., Udeala, O.K. (1975). The surface activity of some antihistamines at the air-solution interface. J Pharm Pharmacol 27(10), 754-58.
7. Attwood, D., Udeala, O.K. (1975). The interaction of antihistamines with lecithin monolayers. J Pharm Pharmacol 27(11), 806-10.
8. Attwood, D., Udeala, O.K. (1976). Aggregation of antihistamines in aqueous solution: effect of counterions on self-association of pyridine derivatives. J Pharm Sci 65(7), 1053-7.
9. Attwood, D., Natarajan, R. (1981). Effect of pH on the micellar properties of amphiphilic drugs in aqueous solution. J Pharm Pharmacol 33(3), 136-40.
10. Attwood, D., Florence, A.T. (1983). Surfactant systems: Their chemistry, pharmacy and biology. Chapman and Hall Ltd., London, p. 124-228, 388-468, 607-610.
11. Attwood, D., Florence, A.T. (1998). Physicochemical principles of pharmacy. Macmillan, London, p. 199-250.
12. Barry, A.L., Craig, W.A., Nadler, H., Reller, L.B., Sanders, C.C., Swenson, J.M. (1999). Methods for Determining Bactericidal Activity of Antimicrobial Agents, Approved Guideline. NCCLS document M26-A, Vol. 19 (18). NCCLS, Pennsylvania, USA.
13. Bettencourt, M.V., Bosne-David, S., Amaral, L. (2000). Comparative in vitro activity of phenothiazines against multidrug-resistant Mycobacterium tuberculosis. Int J Antimicrob Agents 16(1), 69-71.
14. British-Pharmacopoeia-Commission, ed. (2007). Appendix I D. British Pharmacopoeia. The British Stationery Office on behalf of the Medicines and Healthcare products Regulatory Agency (MHRA), London, United Kingdom.
15. Brockman, H.L., Momsen, M.M., Knudtson, J.R., Miller, S.T., Graff, G., Yanni, J.M. (2003). Interactions of olopatadine and selected antihistamines with model and natural membranes. Ocul Immunol Inflamm 11(4), 247-68.
16. Chakrabarty, A.N., Acharya, D.P., Neogi, D., Dastidar, S.G. (1989). Drug interaction of promethazine & other non-conventional antimicrobial chemotherapeutic agents. Indian J Med Res 89, 233-7.
17. Chakrabarty, A.N., Bhattacharya, C.P., Dastidar, S.G. (1993). Antimycobacterial activity of methdilazine (Md), an antimicrobic phenothiazine. Apmis 101(6), 449-54.
18. Chattopadhyay, D., Dastidar, S.G., Chakrabarty, A.N. (1988). Antimicrobial properties of methdilazine and its synergism with antibiotics and some chemotherapeutic agents. Arzneimittelforschung 38(7), 869-72.
19. Collee, J.G., Miles, R.S. (1989). Tests for identification of bacteria. In: Collee, J.G., Duguid, J.P., Fraser, A.G., and Marmion, B.P. (eds). Mackie and McCartney, Practical medical microbiology. Churchill Livingstone, New York, p. 141-160.
20. Dastidar, S.G., Saha, P.K., Sanyamat, B., Chakrabarty, A.N. (1976). Antibacterial activity of ambodryl and benadryl. J Appl Bacteriol 41(2), 209-14.
21. Dastidar, S.G., Jairaj, J., Mookerjee, M., Chakrabarty, A.N. (1997). Studies on antimicrobial effect of the antihistaminic phenothiazine trimeprazine tartrate. Acta Microbiol Immunol Hung 44(3), 241-7.
22. Dominguez, M.C., de La Rosa, M., Borobio, M.V. (2001). Application of a spectrophotometric method for the determination of post-antibiotic effect and comparison with viable counts in agar. J Antimicrob Chemother 47(4), 391-8.
23. Finegold, S.M., Baron, E.J., eds (1986). Bailey and Scott's Diagnostic Microbiology. The C. V. Mosby company, St. Louis, p. 70-125, 173-201, 355-387, 397-437, 859-914.
24. Graff, G., Miller, S.T., Yanni, J.M., Momsen, M.M., Brockman, H.L. (2004). The effects of olopatadine, desloratadine, ketotifen, azelastine, and epinastine on membrane stability. Journal of Allergy and Clinical Immunology 113(2, Supplement 1), S328.
25. Guth, P.S., Spirtes, M.A. (1964). The Phenothiazine tranquilizers: Biochemical and Biophysical Actions. Int Rev Neurobiol 7, 231-78.
26. Howard, D.H. (1956). The preservation of bacteria by freezing in glycerol broth. J Bacteriol 71(5), 625.
27. Kristiansen, J.E., Mortensen, I. (1987). Antibacterial effect of four phenothiazines. Pharmacol Toxicol 60(2), 100-3.
28. Molnar, J., Kiraly, J., Mandi, Y. (1975). The antibacterial action and Rfactor-inhibiting activity by chlorpromazine. Experientia 31(4), 444-5.
29. Molnar, J., Mandi, Y., Kiraly, J. (1976). Antibacterial effect of some phenothiazine compounds and R-factor elimination by chlorpromazine. Acta Microbiol Acad Sci Hung 23(1), 45-54.
30. Semenitz, E. (1978). [The antibacterial activity of diphenhydramine (author's transl)]. Wien Klin Wochenschr 90(19), 710-4.
31. Shibl, A.M., Hammouda, Y., Al-Sowaygh, I. (1984). Comparative effects of selected phenothiazine tranquilizers and antihistaminics on bacterial cells and possible interactions with antibiotics. J Pharm Sci 73(6), 841-3.
32. Simons, F.E. (2004). Advances in H1-antihistamines. N Engl J Med 351(21), 2203-17.
33. Skidgel, R.A., Erdôs, E.G. (2006). Histamine, bradykinin, and their antagonists. In: Brunton, L., Lazo, J., and Parker, K. (eds). Goodman and Gilman's the pharmacological bases of therapeutics. McGraw-Hill medical publishing division, New York, p. 629-652.
34. Sweetman, S.C., ed. (2002). Martindale, the complete drug reference. 33rd ed. Pharmaceutical press, London, p. 110-270, 404-427, 1201-1254.
35. Vandepitt, J., Engbaek, K., Piot, P., Heuck, C.C. (1991). Basic Laboratory Procedures in Clinical Bacteriology. World Health Organization, Geneva, p. 13-15.
36. Viveiros, M., Amaral, L. (2001). Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines. Int J Antimicrob Agents 17(3), 225-8.
37. Zografi, G., Munshi, M.V. (1970). Effect of chemical modification on the surface activity of some phenothiazine derivatives. J Pharm Sci 59(6), 819-22.