68Ga-citrate-PET for diagnostic imaging of infection in rats and for intra-abdominal infection in a patient

Current Radiopharmaceuticals

Volumn 5, Issue 1, 2012, Pages 71-75

  Kumar, Vijay ^a,b,c   Boddeti, Dilip K ^a,b   Evans, Scott G ^a   Angelides, Socrates ^a  

^a WESTMEAD HOSPITAL   (Australia)

^b CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

68Ga Citrate; 68Ga Citrate PET for infection imaging; 68Ga PET; Abdominal infection; Staphylococcus aureus

Indexed keywords

GALLIUM 68; GALLIUM CITRATE; GALLIUM CITRATE GA 67; GALLIUM CITRATE GA 68; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ABDOMINAL INFECTION; ANIMAL EXPERIMENT; ANIMAL MODEL; APPENDECTOMY; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DIAGNOSTIC IMAGING; HUMAN; MALE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; STAPHYLOCOCCUS INFECTION; THIGH;

ANIMALS; APPENDECTOMY; CITRATES; GALLIUM; HUMANS; INTRAABDOMINAL INFECTIONS; MALE; POSITRON-EMISSION TOMOGRAPHY; POSTOPERATIVE COMPLICATIONS; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 83455217856     PISSN: 18744710     EISSN: 18744729     Source Type: Journal    
DOI: 10.2174/1874471011205010071     Document Type: Article

References (22)

1. Ito, Y.; Okuyama, S.; Awano, T.; Takahashi, K.; Sato, T. Diagnostic evaluation of Ga-67 scanning of lung cancer and other diseases. Radiology, 1971, 101, 355-362.
2. 67Ga scintigraphy: procedure guidelines for tumor imaging. Eur. J. Nuc. Med. Mol. Imaging, 2003, 30, BP125-BP131.
3. El-Maghraby, T.A.; Moustafa, H.M.; Pauwels, E.K. Nuclear medicine methods for evaluation of skeletal infection among other diagnostic modalities. Q. J. Nucl. Med. Mol. Imaging, 2006, 50, 167-192.
4. 67Ga-citrate. J. Nucl. Med.Technol., 2003, 31,196-201.
5. Ma, LD.; Frassica, F.J.; Bluemke, D.A.; Fishman, E.K. CT and MRI evaluation of musculoskeletal infection. Crit. Rev. Diagn. Imaging, 1997, 38, 535-568.
6. Boerman, O.C.; Dams, E.T.M.; Oyen, W.J.G.; Corstens, F.H.M.; Storm, G. Radiopharmaceuticals for scintigraphic imaging of infection and inflammations. Inflamm. Res., 2001, 50, 55-64.
7. Hopkins, G.B.; Mende, C.W. Gallium-67 and subphrenic Abscesses -is delayed scintigraphy necessary? J. Nucl. Med., 1975, 16, 609-611.
8. Henkin, R.E. Gallium-67 in the diagnosis of inflammatory disease. In: Gallium-67 Imaging, Hoffer, PB.; Bekerman, C.; Henkin, R.E. Eds., New York, John Wiley and Sons, 1978; pp. 65-92.
9. M.F. Mechanism of gallium-67 accumulation in inflammatory lesions. J. Nucl. Med., 1985, 26, 88-92.
10. 67Ga-Binding Protein in Polymorphonuclear Leukocytes. J. Nucl. Med., 1981, 22, 32-37.
11. Ehrhardt, G.J.; Welch, M.J. A new germanium-68/gallium-68 generator. J. Nucl. Med., 1978, 19, 925-929.
12. 68Ga radiopharmaceutical chemistry. Curr. Topics Med. Chem., 2010; Vol. 10, No.15.
13. Green, M.S.; Welch, M.J. Gallium radiopharmaceutical chemistry. Int. J. Rad. Appl. Instrum. B., 1989, 16, 435-448.
14. 99mTc. Int. J. Appl. Radiat. Isot., 1977, 28, 169-181.
15. 68Ga PET imaging in the assessment of experimental osteomyelitis due to Staphylococcus aureus. Eur. J. Nucl. Med. Mol. Imaging, 2005, 32, 1259-1268.
16. 68Ga-Chloride PET reveals human pancreatic adenocarcinoma xenografts in rats - comparison with FDG. Mol. Imaging Biol., 2009, 12, 259-268.
17. 68Ga-apo-transferrin as a PET imaging agent for detecting Staphylococcus aureus infection. Nuc. Med. Biol., 2011, 38, 393-398.
18. 68Ga citrate for routine clinical PET. Nucl. Med. Comm., 2009, 30, 542-545.
19. 68Ga-Citrate PET/CT for evaluating patients with infections of the bone: preliminary results. J. Nucl. Med., 2010, 51, 1932-1936.
20. 68Ga-Citrate a novel agent for PET-imaging of Staphylococcus aureus infection? Eur. J. Nucl. Med. Mol. Imaging, 2009, 36, (Suppl 2), S194-S233.
21. 68Ga for medical application. J. Nucl. Med., 2007, 48, 1741-1748.
22. Awai, M., Chipman, B., Brown, E.B. In vivo evidence for the functional heterogeneity of transferrin-bound iron. I. Studies in normal rats. J. Lab. Clin. Med., 1975; 85(5), 769-784.