Linear-dendritic polymeric amphiphiles as carriers of doxorubicin-In vitro evaluation of biocompatibility and drug delivery

Journal of Polymer Science, Part A: Polymer Chemistry

Volumn 50, Issue 2, 2012, Pages 217-226

  Wu, Zhihua ^a,b   Zeng, Xianghui ^b   Zhang, Yuning ^b   Feliu, Neus ^b   Lundberg, Pontus ^c   Fadeel, Bengt ^b   Malkoch, Michael ^c   Nyström, Andreas M ^b  

^a NANCHANG UNIVERSITY   (China)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

block copolymers; breast cancer; delivery vehicle; dendrimers; doxorubicin; drug delivery systems; linear dendrimer; primary macrophages

Indexed keywords

AMPHIPHILICS; BREAST CANCER; BREAST CANCER CELLS; CELL APOPTOSIS; CELL UPTAKE; CELL VIABILITY; CELLULAR TOXICITIES; CELLULAR VIABILITY; DELIVERY VEHICLE; DOXORUBICIN; DRUG DELIVERY SYSTEM; DRUG DELIVERY SYSTEMS; DRUG FORMULATIONS; DRUG LOADING; HUMAN MACROPHAGES; HYBRID BLOCK COPOLYMERS; KINETIC STUDY; LOADING EFFICIENCY; NOVEL ARCHITECTURE; POLYMER MICELLES; POLYMERIC AMPHIPHILES; VITRO EVALUATION;

BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; BLOCK COPOLYMERS; CELL CULTURE; CELL DEATH; DENDRIMERS; DISEASES; DRUG DELIVERY; DRUG DOSAGE; MACROPHAGES; MICELLES;

HYBRID MATERIALS;

EID: 83455201299     PISSN: 0887624X     EISSN: 10990518     Source Type: Journal    
DOI: 10.1002/pola.25008     Document Type: Article

References (49)

1. Allen, T. M.; Cullis, P. R., Science 2004, 303, 1818-1822.
2. Dorn, K.; Hoerpel, G.; Ringsdorf, H., In Bioactive Polymeric Systems: An Overview;, Gebelein, C. G.; Carraher, C. E., Jr., Eds.; Plenum Press: New York, 1985; pp 531-585.
3. Ferrari, M., Nat. Rev. Cancer 2005, 5, 161-171.
4. Park, J. H.; Lee, S.; Kim, J. H.; Park, K.; Kim, K.; Kwon, I. C., Prog Polym Sci 2008, 33, 113-137.
5. Iha, R. K.; Wooley, K. L.; Nystrom, A. M.; Burke, D. J.; Kade, M. J.; Hawker, C. J., Chem Rev 2009, 109, 5620-5686.
6. Yokoyama, M., In Polymeric Drug Delivery I: Particulate Drug Carriers, Svenson S., Ed.; 226th National ACS Meeting, New York, 2006; 923, pp 27-39.
7. Gelperina, S.; Kisich, K.; Iseman, M. D.; Heifets, L., Am J Respir Crit Care Med 2005, 172, 1487-1490.
8. Tong, R.; Cheng, J. J., Polym Rev 2007, 47, 345-381.
9. Peer, D.; Karp, J. M.; Hong, S.; Farokhzad, O. C.; Margalit, R.; Langer, R., Nat Nanotechnol 2007, 2, 751-760.
10. Bae, Y. H.; Qiu, L. Y., Pharm Res 2006, 23, 1-30.
11. Emrick, T.; Parrish, B.; Breitenkamp, R. B., J Am Chem Soc 2005, 127, 7404-7410.
12. Wooley, K. L.; Iha, R. K.; Van Horn, B. A., J Polym Sci Part A: Polym Chem 2010, 48, 3553-3563.
13. Tirrell, D. A.; Johnson, J. A.; Lu, Y. Y.; Burts, A. O.; Lim, Y. H.; Finn, M. G.; Koberstein, J. T.; Turro, N. J.; Grubbs, R. H., J Am Chem Soc 2011, 133, 559-566.
14. Cheng, C.; Yu, Y.; Zou, J.; Yu, L.; Jo, W.; Li, Y. K.; Law, W. C., Macromolecules 2011, 44, 4793-4800.
15. Wooley, K. L.; Li, Z.; Ma, J.; Cheng, C.; Zhang, K., Macromolecules 2010, 43, 1182-1184.
16. Wooley, K. L.; Li, Z.; Zhang, K.; Ma, J.; Cheng, C., J Polym Sci Part A: Polym Chem 2009, 47, 5557-5563.
17. Grubbs, R. H.; Johnson, J. A.; Lu, Y. Y.; Burts, A. O.; Xia, Y.; Durrell, A. C.; Tirrell, D. A., Macromolecules 2010, 43, 10326-10335.
18. Cheng, C.; Zou, J. O.; Jafr, G.; Themistou, E.; Yap, Y.; Wintrob, Z. A. P.; Alexandridis, P.; Ceacareanu, A. C., Chem Commun 2011, 47, 4493-4495.
19. Lee, H. I.; Jung, S. H.; Song, H. Y.; Lee, Y.; Jeong, H. M., Macromolecules 2011, 44, 1628-1634.
20. Ohe, K.; Miki, K.; Kimura, A.; Oride, K.; Kuramochi, Y.; Matsuoka, H.; Harada, H.; Hiraoka, M., Angew Chem Int Ed 2011, 50, 6567-6570.
21. Haag, R., Angew Chem Int Ed 2004, 43, 278-282.
22. Matsumura, Y.; Maeda, H., Cancer Res 1986, 46, 6387-6392.
23. Szoka, F. C.; Lee, C. C.; Gillies, E. R.; Fox, M. E.; Guillaudeu, S. J.; Frechet, J. M. J.; Dy, E. E., Proc Natl Acad Sci USA 2006, 103, 16649-16654.
24. Gitsov, I., J Polym Sci Part A: Polym Chem 2008, 46, 5295-5314.
25. Gitsov, I.; Frechet, J. M. J., Macromolecules 1993, 26, 6536-6546.
26. Frechet, J. M. J.; Gitsov, I., Macromol Symp 1995, 98, 441-465.
27. Ofek, P.; Fischer, W.; Calderon, M.; Haag, R.; Satchi-Fainaro, R., FASEB J 2010, 24, 3122-3134.
28. Santini, C. M. B.; Johnson, M. A.; Boedicker, J. Q.; Hatton, T. A.; Hammond, P. T., J Polym Sci Part A: Polym Chem 2004, 42, 2784-2814.
29. Weiss, R. B., Sem Oncol 1992, 19, 670-686.
30. Chlebowski, R. T., West J Med 1979, 131, 364-368.
31. Minotti, G.; Menna, P.; Salvatorelli, E.; Cairo, G.; Gianni, L., Pharmacol Rev 2004, 56, 185-229.
32. O'Brien, M. E. R.; Wigler, N.; Inbar, M.; Rosso, R.; Grischke, E.; Santoro, A.; Catane, R.; Kieback, D. G.; Tomczak, P.; Ackland, S. P.; Orlandi, F.; Mellars, L.; Alland, L.; Tendler, C.; Grp, C. B. C. S., Ann Oncol 2004, 15, 440-449.
33. Lundberg, P.; Walter, M. V.; Montañez, M. I.; Hult, D.; Hult, A.; Nyström, A.; Malkoch, M., Polym Chem 2011, 2, 394-402.
34. Ropponen, J.; Hyvonen, Z.; Ruponen, M.; Jarvinen, K.; Malkoch, M.; Malmstrom, E., Eur J Pharm Sci 2008, 34, S36-S36.
35. Kohn, J.; Abramson, S.; Langer, R., In Biomaterials Science-An Introduction to Materials in Medicine;, Ratner, B. D.; Hoffman, A. S.; Schoen, F. J.; Lemons, J. E., Eds.; Elsevier Academic Press: London, UK, 2004; pp 115-127.
36. Peppas, N. A., In Biomaterials Science-An Introduction to Materials in Medicine;, Ratner, B. D.; Hoffman, A. S.; Schoen, F. J.; Lemons, J. E., Eds.; Elsevier Academic Press: London, UK, 2004; pp 110-107.
37. Nunez, E.; Ferrando, C.; Malmstrom, E.; Claesson, H.; Werner, P. E.; Gedde, U. W., Polymer 2004, 45, 5251-5263.
38. Nystrom, A. M.; Wooley, K. L., Soft Matter 2008, 4, 849-858.
39. Geiser, M., J Aerosol Med Pulm Drug Deliv 2010, 23, 207-217.
40. Kunzmann, A.; Andersson, B.; Thurnherr, T.; Krug, H.; Scheynius, A.; Fadeel, B., Biochim Biophys Acta 2011, 1810, 361-373.
41. Naha, P. C.; Davoren, M.; Lyng, F. M.; Byrne, H. J., Toxicol Appl Pharmacol 2010, 246, 91-99.
42. Mukherjee, S. P.; Davoren, M.; Byrne, H. J., Toxicol In Vitro 2010, 24, 169-177.
43. Mamot, C.; Drummond, D. C.; Greiser, U.; Hong, K.; Kirpotin, D. B.; Marks, J. D.; Park, J. W., Cancer Res 2003, 63, 3154-3161.
44. Abraham, S.; Guo, F.; Li, L. S.; Rader, C.; Liu, C.; Barbas, C. F.; Lerner, R. A.; Sinha, S. C., Proc Natl Acad Sci USA 2007, 104, 5584-5589.
45. Nystrom, A. M.; Xu, Z. Q.; Xu, J. Q.; Taylor, S.; Nittis, T.; Stewart, S. A.; Leonard, J.; Wooley, K. L., Chem Commun 2008, 3579-3581.
46. Aroui, S.; Brahim, S.; Waard, M. D.; Kenani, A., Biochem Biophys Res Commun 2010, 391, 419-425.
47. Yim, H.; Na, K., Biomacromolecules 2010, 11, 2387-2393.
48. Witasp, E.; Shvedova, A. A.; Kagan, V. E.; Fadeel, B., Inhal Toxicol 2009, 21 (Suppl 1), 131-136.
49. Cory, A. H.; Owen, T. C.; Barltrop, J. A.; Cory, J. G., Cancer Commun 1991, 3, 207-212.