Development and validation of high-performance liquid chromatography/electrospray ionization mass spectrometry for assay of madecassoside in rat plasma and its application to pharmacokinetic study

Biomedical Chromatography

Volumn 26, Issue 1, 2012, Pages 26-32

  Han, Wen Jing ^a   Xia, Yu Feng ^a   Dai, Yue ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

LC ESI MS; Madecassoside; Pharmacokinetics; Plasma

Indexed keywords

BODY FLUIDS; ELECTRODEPOSITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; RATS;

HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; INTERNAL STANDARDS; ITS APPLICATIONS; LIQUID CHROMATOGRAPHY ELECTROSPRAY; LIQUID CHROMATOGRAPHY-ELECTROSPRAY IONIZATION-MASS SPECTROMETRIES; LIQUID CHROMATOGRAPHY/ELECTROSPRAY IONIZATION MASS SPECTROMETRIC; MADECASSOSIDE; PHARMACOKINETIC STUDIES; PLASMA SAMPLES; RAT PLASMA;

ELECTROSPRAY IONIZATION;

ACETONITRILE; CENTELLA ASIATICA EXTRACT; HERBACEOUS AGENT; MADECASSOSIDE; PAEONIFLORIN; UNCLASSIFIED DRUG; WATER;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTELLA ASIATICA; CHROMATOGRAPHY; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF QUANTITATION; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PLASMA; RAT; SENSITIVITY AND SPECIFICITY; STANDARD; VALIDATION STUDY;

EID: 83455197418     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1620     Document Type: Article

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