The frequency of 'atypia of undetermined significance' interpretations for thyroid fine-needle aspirations is negatively correlated with histologically proven malignant outcomes

Acta Cytologica

Volumn 55, Issue 6, 2011, Pages 512-517

  Vanderlaan, Paul A ^a   Krane, Jeffrey F ^a   Cibas, Edmund S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Atypia of undetermined significance; Cytology; Fine needle aspiration; Thyroid

Indexed keywords

ARTICLE; ASPIRATION BIOPSY; ATYPIA OF UNDETERMINED SIGNIFICANCE; CELL DAMAGE; CORRELATION ANALYSIS; CYTOPATHOLOGY; HISTOPATHOLOGY; HUMAN; NEOPLASM; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TERTIARY HEALTH CARE; THYROID FINE NEEDLE ASPIRATION;

EID: 83455181438     PISSN: 00015547     EISSN: 19382650     Source Type: Journal    
DOI: 10.1159/000333231     Document Type: Article

References (21)

1. Cibas ES, Ali SZ, NCI Thyroid FNA State of the Science Conference: The Bethesda System for Reporting Thyroid Cytopathology. Am J Clin Pathol 2009; 132: 658-665.
2. Ali SZ, Cibas ES: The Bethesda System for Reporting Thyroid Cytopathology, ed 1. New York, Springer, 2010.
3. Yassa L, Cibas ES, Benson CB, Frates MC, Doubilet PM, Gawande AA, Moore FD, Kim BW, Nosé V, Marqusee E, Larsen PR, Alexander EK: Long-term assessment of a multidisciplinary approach to thyroid nodule diagnostic evaluation. Cancer Cytopathol 2007; 111: 508-516. (Pubitemid 350304903)
4. Yang J, Schnadig V, Logrono R, Wasserman PG: Fine-needle aspiration of thyroid nodules: a study of 4,703 patients with histologic and clinical correlations. Cancer 2007; 111: 306-315.
5. Krane JF, Vanderlaan PA, Faquin WC, Renshaw AA: The atypia of undetermined significance/follicular lesion of undetermined significance: malignant ratio: a proposed performance measure for reporting in the Bethesda System for Thyroid Cytopathology. Cancer Cytopathol 2011, DOI: 10.1002/cncy.20192.
6. Layfield LJ, Morton MJ, Cramer HM, Hirschowitz S: Implications of the proposed thyroid fine-needle aspiration category of 'follicular lesion of undetermined significance': a five-year multi-institutional analysis. Diagn Cytopathol 2009; 37: 710-714.
7. Nayar R, Ivanovic M: The indeterminate thyroid fine-needle aspiration: experience from an academic center using terminology similar to that proposed in the 2007 National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference. Cancer Cytopathol 2009; 117: 195-202.
8. Theoharis CG, Schofield KM, Hammers L, Udelsman R, Chhieng DC: The Bethesda thyroid fine-needle aspiration classification system: year 1 at an academic institution. Thyroid 2009; 19: 1215-1223.
9. Shi Y, Ding X, Klein M, Sugrue C, Matano S, Edelman M, Wasserman P: Thyroid fineneedle aspiration with atypia of undetermined significance: a necessary or optional category? Cancer Cytopathol 2009; 117: 298-304.
10. Renshaw AA: Should 'atypical follicular cells' in thyroid fine-needle aspirates be subclassified? Cancer Cytopathol 2010; 118: 186-189.
11. Jo VY, Stelow EB, Dustin SM, Hanley KZ: Malignancy risk for fine-needle aspiration of thyroid lesions according to the Bethesda System for Reporting Thyroid Cytopathology. Am J Clin Pathol 2010; 134: 450-456.
12. Somma J, Schlecht NF, Fink D, Khader SN, Smith RV, Cajigas A: Thyroid fine needle aspiration cytology: follicular lesions and the gray zone. Acta Cytol 2010; 54: 123-131.
13. Marchevsky AM, Walts AE, Bose S, Gupta R, Fan X, Frishberg D, Scharre K, Zhai J: Evidence-based evaluation of the risks of malignancy predicted by thyroid fine-needle aspiration biopsies. Diagn Cytopathol 2010; 38: 252-259.
14. Vanderlaan PA, Marqusee E, Krane JF: Clinical outcome for atypia of undetermined significance in thyroid fine-needle aspirations: should repeated FNA be the preferred initial approach? Am J Clin Pathol 2011; 135: 770-775.
15. Faquin WC, Baloch ZW: Fine-needle aspiration of follicular patterned lesions of the thyroid: diagnosis, management, and followup according to National Cancer Institute (NCI) recommendations. Diagn Cytopathol 2010; 38: 731-739.
16. Jing X, Knoepp SM, Roh MH, Hookim K, Placido J, Davenport R, Rasche R, Michael CW: Group consensus review minimizes the diagnosis of 'follicular lesion of undetermined significance' and improves cytohistologic concordance. Diagn Cytopathol 2011, DOI: 10.1002/dc.21702.
17. Jing X, Roh MH, Knoepp SM, Zhao L, Michael CW: Minimizing the diagnosis of 'follicular lesion of undetermined significance' and identifying predictive features for neoplasia. Diagn Cytopathol 2010; 39: 737-742.
18. Juskevicius R, Zou KH, Cibas ES: An analysis of factors that influence the ASCUS/SIL ratio of pathologists. Am J Clin Pathol 2001; 116: 331-335. (Pubitemid 32851964)
19. Nascimento AF, Cibas ES: The ASC/SIL ratio for cytopathologists as a quality control measure: a follow-up study. Am J Clin Pathol 2007; 128: 653-656. (Pubitemid 47584445)
20. Abele JS, Levine RA: Diagnostic criteria and risk-adapted approach to indeterminate thyroid cytodiagnosis. Cancer Cytopathol 2010; 118: 415-422.
21. Koen TM, Mody DR, Scheiber-Pacht M, Fairley T, Thrall MJ: Limiting the use of atypical/inconclusive as a category in nongynecologic cytology specimens. Arch Pathol Lab Med 2010; 134: 1016-1019.