A case of trimebutine-induced anaphylaxis

Allergology International

Volumn 60, Issue 4, 2011, Pages 555-556

  Lee, Suh Young ^a   Kim, Mi Yeong ^a   Kang, Sung Yoon ^a   Song, Woo Jung ^a   Kang, Hye Ryun ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

Anaphylaxis; Drug hypersensitivity; Trimebutine

Indexed keywords

ACECLOFENAC; ACETYLSALICYLIC ACID; CEFACLOR; CHLORPHENIRAMINE; DEXAMETHASONE; SODIUM CHLORIDE; TRIMEBUTINE MALEATE;

ABSENCE OF SIDE EFFECTS; ADULT; ANAPHYLAXIS; ARTICLE; CASE REPORT; DIZZINESS; DRUG HYPERSENSITIVITY; DYSPNEA; ERYTHEMA; FEMALE; HUMAN; INTRACUTANEOUS TEST; PATIENT POSITIONING; PRIORITY JOURNAL; PRURITUS;

EID: 83455172570     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.10-CR-0289     Document Type: Article

References (10)

1. Roman FJ, Lanet S, Hamon J et al. Pharmacological properties of trimebutine and N-monodesmethyltrimebutine. J Pharmacol Exp Ther 1999;289:1391-7.
2. Delvaux M, Wingate D. Trimebutine: mechanism of action, effects on gastrointestinal function and clinical results. J IntMed Res 1997;25:225-46.
3. Luttecke K. A three-part controlled study of trimebutine in the treatment of irritable colon syndrome. Curr Med Res Opin 1980;6:437-43.
4. Tanaka M. Gastric ulcer, motility, and trimebutine. J Gastroenterol 1998;33:916-7.
5. Kountouras J, Chatzopoulos D, Zavos C, Boura P, Venizelos J, Kalis A. Efficacy of trimebutine therapy in patients with gastroesophageal reflux disease and irritable bowel syndrome. Hepatogastroenterology 2002;49:193-7.
6. Long Y, Liu Y, Tong J, Qian W, Hou X. Effectiveness of trimebutine maleate on modulating intestinal hypercontractility in a mouse model of postinfectious irritable bowel syndrome. Eur J Pharmacol 2010;636:159-65.
7. Martin-Garcia C, Martinez-Borque N, Martinez-Bohigas D, Torrecillas-Toro M, Palomeque-Rodriguez MT. Delayed reaction urticaria due to trimebutine. Allergy 2004; 59:789-90.
8. Reyes JJ, Farina MC. Allergic contact dermatitis due to trimebutine. Contact Dermatitis 2001;45:164.
9. Van der Klauw MM, Stricker BH, Herings RM, Cost WS, Valkenburg HA, Wilson JH. A population based casecohort study of drug-induced anaphylaxis. Br J Clin Pharmacol 1993;35:400-8.
10. Limsuwan T, Demoly P. Acute symptoms of drug hypersensitivity (urticaria, angioedema, anaphylaxis, anaphylactic shock). Med Clin North Am 2010;94:691-710.