메뉴 건너뛰기




Volumn 16, Issue 8, 2011, Pages 1187-1201

Impact of HCV protease-inhibitor-based triple therapy for chronic HCV genotype 1 infection

Author keywords

[No Author keywords available]

Indexed keywords

BOCEPREVIR; CYCLOSPORIN; ESCITALOPRAM; ORAL CONTRACEPTIVE AGENT; PEGINTERFERON; PEGINTERFERON ALPHA2A; PEGINTERFERON ALPHA2B; PLACEBO; RIBAVIRIN; TACROLIMUS; TELAPREVIR;

EID: 83455163791     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: 10.3851/IMP1934     Document Type: Review
Times cited : (32)

References (55)
  • 1
    • 65449136656 scopus 로고    scopus 로고
    • Diagnosis, management, and treatment of hepatitis C: An update
    • Ghany MG, Strader DB, Thomas DL, Seeff LB. Diagnosis, management, and treatment of hepatitis C: an update. Hepatology 2009; 49:1335-1374.
    • (2009) Hepatology , vol.49 , pp. 1335-1374
    • Ghany, M.G.1    Strader, D.B.2    Thomas, D.L.3    Seeff, L.B.4
  • 2
    • 79959353386 scopus 로고    scopus 로고
    • Portal pressure predicts outcome and safety of antiviral therapy in cirrhotic patients with hepatitis C virus infection
    • Reiberger T, Rutter K, Ferlitsch A, et al. Portal pressure predicts outcome and safety of antiviral therapy in cirrhotic patients with hepatitis C virus infection. Clin Gastroenterol Hepatol 2011; 9:602-608.e1.
    • (2011) Clin Gastroenterol Hepatol , vol.9
    • Reiberger, T.1    Rutter, K.2    Ferlitsch, A.3
  • 3
    • 79955103901 scopus 로고    scopus 로고
    • Treatment failure and resistance with direct-acting antiviral drugs against hepatitis C virus
    • Pawlotsky JM. Treatment failure and resistance with direct-acting antiviral drugs against hepatitis C virus. Hepatology 2011; 53:1742-1751.
    • (2011) Hepatology , vol.53 , pp. 1742-1751
    • Pawlotsky, J.M.1
  • 4
    • 79958830099 scopus 로고    scopus 로고
    • Hepatitis C virus resistance to protease inhibitors
    • Halfon P, Locarnini S. Hepatitis C virus resistance to protease inhibitors. J Hepatol 2011; 55:192-206.
    • (2011) J Hepatol , vol.55 , pp. 192-206
    • Halfon, P.1    Locarnini, S.2
  • 5
    • 79952307519 scopus 로고    scopus 로고
    • The results of Phase III clinical trials with telaprevir and boceprevir presented at the Liver Meeting 2010: A new standard of care for hepatitis C virus genotype 1 infection, but with issues still pending
    • Pawlotsky JM. The results of Phase III clinical trials with telaprevir and boceprevir presented at the Liver Meeting 2010: a new standard of care for hepatitis C virus genotype 1 infection, but with issues still pending. Gastroenterology 2011; 140:746-754.
    • (2011) Gastroenterology , vol.140 , pp. 746-754
    • Pawlotsky, J.M.1
  • 6
    • 65449171953 scopus 로고    scopus 로고
    • Telaprevir and peginterferon with or without ribavirin for chronic HCV infection
    • Hézode C, Forestier N, Dusheiko G, et al. Telaprevir and peginterferon with or without ribavirin for chronic HCV infection. N Engl J Med 2009; 360:1839-1850.
    • (2009) N Engl J Med , vol.360 , pp. 1839-1850
    • Hézode, C.1    Forestier, N.2    Dusheiko, G.3
  • 7
    • 78049527728 scopus 로고    scopus 로고
    • Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): A randomised, double-blind, placebo-controlled, dose-escalation trial
    • Gane EJ, Roberts SK, Stedman CA, et al. Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial. Lancet 2010; 376:1467-1475.
    • (2010) Lancet , vol.376 , pp. 1467-1475
    • Gane, E.J.1    Roberts, S.K.2    Stedman, C.A.3
  • 8
    • 78650928650 scopus 로고    scopus 로고
    • Combination therapy with BMS-790052 and BMS-650032 alone or with PEGIFN/RBV results in undetectable HCV RNA through 12 weeks of therapy in HCV genotype 1 null responders
    • Lok A, Gardiner D, Lawitz E, et al. Combination therapy with BMS-790052 and BMS-650032 alone or with PEGIFN/RBV results in undetectable HCV RNA through 12 weeks of therapy in HCV genotype 1 null responders. Hepatology 2010; 52 Suppl 1:877A.
    • (2010) Hepatology , vol.52 , Issue.SUPPL. 1
    • Lok, A.1    Gardiner, D.2    Lawitz, E.3
  • 9
    • 78650957102 scopus 로고    scopus 로고
    • Dual, triple, and quadruple combination treatment with a protease inhibitor (GS-9256) and a polymerase inhibitor (GS-9190) alone and in combination with ribavirin (RBV) or PEGIFN/RBV for up to 28 days in treatment naive genotype 1 HCV subjects
    • Zeuzem S, Buggisch P, Agarwal K, et al. Dual, triple, and quadruple combination treatment with a protease inhibitor (GS-9256) and a polymerase inhibitor (GS-9190) alone and in combination with ribavirin (RBV) or PEGIFN/RBV for up to 28 days in treatment naive genotype 1 HCV subjects. Hepatology 2010; 52 Suppl 1:400A.
    • (2010) Hepatology , vol.52 , Issue.SUPPL. 1
    • Zeuzem, S.1    Buggisch, P.2    Agarwal, K.3
  • 10
    • 79952233518 scopus 로고    scopus 로고
    • Insurance status and treatment candidacy of hepatitis C patients: Analysis of population-based data from the United States
    • Stepanova M, Kanwal F, El-Serag HB, Younossi ZM. Insurance status and treatment candidacy of hepatitis C patients: analysis of population-based data from the United States. Hepatology 2011; 53:737-745.
    • (2011) Hepatology , vol.53 , pp. 737-745
    • Stepanova, M.1    Kanwal, F.2    El-Serag, H.B.3    Younossi, Z.M.4
  • 11
    • 83455175563 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis C genotype 1 patients at an academic center in Europe involved in prospective controlled trials - Is there a selection bias?
    • doi: 10.1002/hep.24671
    • Beinhardt S, Staettermayer A, Rutter K, et al. Treatment of chronic hepatitis C genotype 1 patients at an academic center in Europe involved in prospective controlled trials - is there a selection bias? Hepatology 2011; doi: 10.1002/hep.24671
    • (2011) Hepatology
    • Beinhardt, S.1    Staettermayer, A.2    Rutter, K.3
  • 12
    • 79953755225 scopus 로고    scopus 로고
    • Insurance status and treatment candidacy of patients with hepatitis C: Taiwanese patients are luckier
    • Dai CY, Yeh ML, Huang JF, Chuang WL, Yu ML. Insurance status and treatment candidacy of patients with hepatitis C: Taiwanese patients are luckier. Hepatology 2011; 53:1399.
    • (2011) Hepatology , vol.53 , pp. 1399
    • Dai, C.Y.1    Yeh, M.L.2    Huang, J.F.3    Chuang, W.L.4    Yu, M.L.5
  • 13
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir for untreated chronic HCV genotype 1 infection
    • Poordad F, McCone J, Jr., Bacon BR, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011; 364:1195-1206.
    • (2011) N Engl J Med , vol.364 , pp. 1195-1206
    • Poordad, F.1    McCone Jr., J.2    Bacon, B.R.3
  • 14
    • 79959438789 scopus 로고    scopus 로고
    • Telaprevir for previously untreated chronic hepatitis C virus infection
    • Jacobson IM, McHutchison JG, Dusheiko G, et al. Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med 2011; 364:2405-2416.
    • (2011) N Engl J Med , vol.364 , pp. 2405-2416
    • Jacobson, I.M.1    McHutchison, J.G.2    Dusheiko, G.3
  • 15
    • 80052826527 scopus 로고    scopus 로고
    • Response-guided telaprevir combination treatment for hepatitis C virus infection
    • Sherman KE, Flamm SL, Afdhal NH, et al. Response-guided telaprevir combination treatment for hepatitis C virus infection. N Engl J Med 2011; 365:1014-1024.
    • (2011) N Engl J Med , vol.365 , pp. 1014-1024
    • Sherman, K.E.1    Flamm, S.L.2    Afdhal, N.H.3
  • 16
    • 77956268467 scopus 로고    scopus 로고
    • Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): An open-label, randomised, multicentre Phase 2 trial
    • Kwo PY, Lawitz EJ, McCone J, et al. Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre Phase 2 trial. Lancet 2010; 376:705-716.
    • (2010) Lancet , vol.376 , pp. 705-716
    • Kwo, P.Y.1    Lawitz, E.J.2    McCone, J.3
  • 17
    • 79251554986 scopus 로고    scopus 로고
    • Telaprevir is effective given every 8 or 12 hours with ribavirin and peginterferon alfa-2a or -2b to patients with chronic hepatitis C
    • Marcellin P, Forns X, Goeser T, et al. Telaprevir is effective given every 8 or 12 hours with ribavirin and peginterferon alfa-2a or -2b to patients with chronic hepatitis C. Gastroenterology 2011; 140:459-468.e1.
    • (2011) Gastroenterology , vol.140
    • Marcellin, P.1    Forns, X.2    Goeser, T.3
  • 18
    • 79953176289 scopus 로고    scopus 로고
    • Boceprevir for previously treated chronic HCV genotype 1 infection
    • Bacon BR, Gordon SC, Lawitz E, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011; 364:1207-1217.
    • (2011) N Engl J Med , vol.364 , pp. 1207-1217
    • Bacon, B.R.1    Gordon, S.C.2    Lawitz, E.3
  • 19
    • 83455265360 scopus 로고    scopus 로고
    • High sustained virologic response (SVR) among genotype 1 previous non-responders and relapsers to peginterferon/ribavirin when re-treated with boceprevir (BOC) plus peginterferon alfa-2a/ribavirin
    • Abstract 1366
    • Flamm S, Lawitz E, Jacobson I, et al. High sustained virologic response (SVR) among genotype 1 previous non-responders and relapsers to peginterferon/ribavirin when re-treated with boceprevir (BOC) plus peginterferon alfa-2a/ribavirin. 46th Annual Meeting of the European Association for the Study of the Liver. 30 March - 3 April 2011, Berlin, Germany. Abstract 1366.
    • 46th Annual Meeting of the European Association for the Study of the Liver. 30 March - 3 April 2011, Berlin, Germany
    • Flamm, S.1    Lawitz, E.2    Jacobson, I.3
  • 20
    • 79959381354 scopus 로고    scopus 로고
    • Telaprevir for retreatment of HCV infection
    • Zeuzem S, Andreone P, Pol S, et al. Telaprevir for retreatment of HCV infection. N Engl J Med 2011; 364:2417-2428.
    • (2011) N Engl J Med , vol.364 , pp. 2417-2428
    • Zeuzem, S.1    Andreone, P.2    Pol, S.3
  • 21
    • 79958195203 scopus 로고    scopus 로고
    • Outcomes of treatment for hepatitis C virus infection by primary care providers
    • Arora S, Thornton K, Murata G, et al. Outcomes of treatment for hepatitis C virus infection by primary care providers. N Engl J Med 2011; 364:2199-2207.
    • (2011) N Engl J Med , vol.364 , pp. 2199-2207
    • Arora, S.1    Thornton, K.2    Murata, G.3
  • 25
    • 79958816097 scopus 로고    scopus 로고
    • Rapid virological response is the most important predictor of sustained virological response across genotypes in patients with chronic hepatitis C virus infection
    • Fried MW, Hadziyannis SJ, Shiffman ML, Messinger D, Zeuzem S. Rapid virological response is the most important predictor of sustained virological response across genotypes in patients with chronic hepatitis C virus infection. J Hepatol 2011; 55:69-75.
    • (2011) J Hepatol , vol.55 , pp. 69-75
    • Fried, M.W.1    Hadziyannis, S.J.2    Shiffman, M.L.3    Messinger, D.4    Zeuzem, S.5
  • 26
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge D, Fellay J, Thompson AJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009; 461:399-401.
    • (2009) Nature , vol.461 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3
  • 27
    • 83455166816 scopus 로고    scopus 로고
    • Package insert Schering Corporation a subsidiary of Merck and Co., Whitehouse Station, NJ, USA
    • Victrelis prescribing information. Package insert 2011. Schering Corporation a subsidiary of Merck and Co., Whitehouse Station, NJ, USA.
    • (2011) Victrelis Prescribing Information
  • 28
    • 83455160674 scopus 로고    scopus 로고
    • Package insert Vertex pharmaceuticals Inc., Cambridge, MA, USA
    • Incivek prescribing information. Package insert 2011. Vertex pharmaceuticals Inc., Cambridge, MA, USA.
    • (2011) Incivek Prescribing Information
  • 29
    • 77953881002 scopus 로고    scopus 로고
    • Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus
    • Thompson AJ, Muir AJ, Sulkowski MS, et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology 2010; 139:120-129.e18.
    • (2010) Gastroenterology , vol.139
    • Thompson, A.J.1    Muir, A.J.2    Sulkowski, M.S.3
  • 30
    • 79961041471 scopus 로고    scopus 로고
    • Impact of IL28B genotype and pre-treatment serum IP-10 in treatment-naive genotype 1 HCV patients treated with TMC435 in combination with peginterferon alpha-2a and ribavirin in the PILLAR study
    • Aerssens J, Fanning G, Scholliers A, et al. Impact of IL28B genotype and pre-treatment serum IP-10 in treatment-naive genotype 1 HCV patients treated with TMC435 in combination with peginterferon alpha-2a and ribavirin in the PILLAR study. J Hepatol 2011; 54 Suppl 1:S5.
    • (2011) J Hepatol , vol.54 , Issue.SUPPL. 1
    • Aerssens, J.1    Fanning, G.2    Scholliers, A.3
  • 32
    • 80053477775 scopus 로고    scopus 로고
    • Anemia during treatment with peginterferon alfa-2b/ribavirin with or without boceprevir is associated with higher SVR rates: Analysis of previously untreated and previous-treatment-failure patients
    • Sulkowski MS, Poordad F, Manns MP, et al. Anemia during treatment with peginterferon alfa-2b/ribavirin with or without boceprevir is associated with higher SVR rates: analysis of previously untreated and previous-treatment- failure patients. J Hepatol 2011; 54 Suppl 1:S194.
    • (2011) J Hepatol , vol.54 , Issue.SUPPL. 1
    • Sulkowski, M.S.1    Poordad, F.2    Manns, M.P.3
  • 33
    • 79959561437 scopus 로고    scopus 로고
    • Effect of telaprevir on the pharmacokinetics of cyclosporine and tacrolimus
    • Garg V, Van HR, Lee JE, Alves K, Nadkarni P, Luo X. Effect of telaprevir on the pharmacokinetics of cyclosporine and tacrolimus. Hepatology 2011; 54:20-27.
    • (2011) Hepatology , vol.54 , pp. 20-27
    • Garg, V.1    Van, H.R.2    Lee, J.E.3    Alves, K.4    Nadkarni, P.5    Luo, X.6
  • 34
    • 80052836825 scopus 로고    scopus 로고
    • Effect of the hepatitis C virus protease inhibitor telaprevir on the pharmacokinetics of amlodipine and atorvastatin
    • doi: 10.1128/AAC.00653-11
    • Lee JE, Van HR, Alves K, Smith F, Garg V. Effect of the hepatitis C virus protease inhibitor telaprevir on the pharmacokinetics of amlodipine and atorvastatin. Antimicrob Agents Chemother 2011; doi: 10.1128/AAC.00653-11
    • (2011) Antimicrob Agents Chemother
    • Lee, J.E.1    Van, H.R.2    Alves, K.3    Smith, F.4    Garg, V.5
  • 36
    • 58149388300 scopus 로고    scopus 로고
    • Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naive patients
    • Kuntzen T, Timm J, Berical A, et al. Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naive patients. Hepatology 2008; 48:1769-1778.
    • (2008) Hepatology , vol.48 , pp. 1769-1778
    • Kuntzen, T.1    Timm, J.2    Berical, A.3
  • 37
    • 65449157987 scopus 로고    scopus 로고
    • Hepatitis C virus drug resistance and immune-driven adaptations: Relevance to new antiviral therapy
    • Gaudieri S, Rauch A, Pfafferott K, et al. Hepatitis C virus drug resistance and immune-driven adaptations: relevance to new antiviral therapy. Hepatology 2009; 49:1069-1082.
    • (2009) Hepatology , vol.49 , pp. 1069-1082
    • Gaudieri, S.1    Rauch, A.2    Pfafferott, K.3
  • 38
    • 82955172365 scopus 로고    scopus 로고
    • Molecular characterization of HCV resistance to telaprevir by means of ultra-deep pyrosequencing: Preexisting resistant variants and dynamics of resistant populations
    • Chevaliez S, Rodriguez C, Soulier A, Ahmed-Belkacem A, Hézode C, Pawlotsky J-M. Molecular characterization of HCV resistance to telaprevir by means of ultra-deep pyrosequencing: preexisting resistant variants and dynamics of resistant populations. J Hepatol 2011; 54 Suppl 1:S30.
    • (2011) J Hepatol , vol.54 , Issue.SUPPL. 1
    • Chevaliez, S.1    Rodriguez, C.2    Soulier, A.3    Ahmed-Belkacem, A.4    Hézode, C.5    Pawlotsky, J.-M.6
  • 39
    • 77953013128 scopus 로고    scopus 로고
    • Rapid emergence of protease inhibitor resistance in hepatitis C virus
    • Rong L, Dahari H, Ribeiro RM, Perelson AS. Rapid emergence of protease inhibitor resistance in hepatitis C virus. Sci Transl Med 2010; 2:30ra32.
    • (2010) Sci Transl Med , vol.2
    • Rong, L.1    Dahari, H.2    Ribeiro, R.M.3    Perelson, A.S.4
  • 41
    • 66149128046 scopus 로고    scopus 로고
    • GT-1a or GT-1b subtype-specific resistance profiles for hepatitis C virus inhibitors telaprevir and HCV-796
    • McCown MF, Rajyaguru S, Kular S, Cammack N, Najera I. GT-1a or GT-1b subtype-specific resistance profiles for hepatitis C virus inhibitors telaprevir and HCV-796. Antimicrob Agents Chemother 2009; 53:2129-2132.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 2129-2132
    • McCown, M.F.1    Rajyaguru, S.2    Kular, S.3    Cammack, N.4    Najera, I.5
  • 42
    • 79951630741 scopus 로고    scopus 로고
    • Long-term follow-up of patients with chronic hepatitis C treated with telaprevir in combination with peginterferon alfa-2a and ribavirin: Interim analysis of the EXTEND study
    • Zeuzem S, Sulkowski M, Zoulim F, et al. Long-term follow-up of patients with chronic hepatitis C treated with telaprevir in combination with peginterferon alfa-2a and ribavirin: interim analysis of the EXTEND study. Hepatology 2010; 52 Suppl 1:436A.
    • (2010) Hepatology , vol.52 , Issue.SUPPL. 1
    • Zeuzem, S.1    Sulkowski, M.2    Zoulim, F.3
  • 43
    • 83455180899 scopus 로고    scopus 로고
    • Durability of response and rate of reemergence of wild type at BOC resistance-associated variant loci in genotype-1a and -1b patients: Interim analysis of long-term follow-up of patients treated with BOC+pegIFN/RBV
    • Abstract 117
    • Barnard R, Howe J, Graham D, et al. Durability of response and rate of reemergence of wild type at BOC resistance-associated variant loci in genotype-1a and -1b patients: interim analysis of long-term follow-up of patients treated with BOC+pegIFN/RBV. 18th Conference on Retroviruses and Opportunistic Infections. 27 February-2 March 2011, Boston, MA, USA. Abstract 117.
    • 18th Conference on Retroviruses and Opportunistic Infections. 27 February-2 March 2011, Boston, MA, USA
    • Barnard, R.1    Howe, J.2    Graham, D.3
  • 44
    • 77957952655 scopus 로고    scopus 로고
    • Randomized trial of peginterferon alfa-2b and ribavirin for 48 or 72 weeks in patients with hepatitis C virus genotype 1 and slow virologic response
    • Buti M, Lurie Y, Zakharova NG, et al. Randomized trial of peginterferon alfa-2b and ribavirin for 48 or 72 weeks in patients with hepatitis C virus genotype 1 and slow virologic response. Hepatology 2010; 52:1201-1207.
    • (2010) Hepatology , vol.52 , pp. 1201-1207
    • Buti, M.1    Lurie, Y.2    Zakharova, N.G.3
  • 46
    • 33645992473 scopus 로고    scopus 로고
    • Extended treatment duration for hepatitis C virus type 1: Comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin
    • Berg T, von Wagner M, Nasser S, et al. Extended treatment duration for hepatitis C virus type 1: comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin. Gastroenterology 2006; 130:1086-1097.
    • (2006) Gastroenterology , vol.130 , pp. 1086-1097
    • Berg, T.1    Von Wagner, M.2    Nasser, S.3
  • 48
    • 68249154875 scopus 로고    scopus 로고
    • Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection
    • McHutchison JG, Lawitz EJ, Shiffman ML, et al. Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection. N Engl J Med 2009; 361:580-593.
    • (2009) N Engl J Med , vol.361 , pp. 580-593
    • McHutchison, J.G.1    Lawitz, E.J.2    Shiffman, M.L.3
  • 49
    • 48749099989 scopus 로고    scopus 로고
    • Peginterferon alfa-2a and ribavirin for 24 weeks in hepatitis C type 1 and 4 patients with rapid virological response
    • Ferenci P, Laferl H, Scherzer TM, et al. Peginterferon alfa-2a and ribavirin for 24 weeks in hepatitis C type 1 and 4 patients with rapid virological response. Gastroenterology 2008; 135:451-458.
    • (2008) Gastroenterology , vol.135 , pp. 451-458
    • Ferenci, P.1    Laferl, H.2    Scherzer, T.M.3
  • 51
    • 46249114151 scopus 로고    scopus 로고
    • Rapid virological response and treatment duration for chronic hepatitis C genotype 1 patients: A randomized trial
    • Yu ML, Dai CY, Huang JF, et al. Rapid virological response and treatment duration for chronic hepatitis C genotype 1 patients: a randomized trial. Hepatology 2008; 47:1884-1893.
    • (2008) Hepatology , vol.47 , pp. 1884-1893
    • Yu, M.L.1    Dai, C.Y.2    Huang, J.F.3
  • 52
    • 84984562129 scopus 로고    scopus 로고
    • Pegylated interferon-alpha-2a plus ribavirin for treatment-naive Asian patients with hepatitis C virus genotype 1 infection: A multicenter, randomized controlled trial
    • Liu CH, Liu CJ, Lin CL, et al. Pegylated interferon-alpha-2a plus ribavirin for treatment-naive Asian patients with hepatitis C virus genotype 1 infection: a multicenter, randomized controlled trial. Clin Infect Dis 2008; 47:1260-1269.
    • (2008) Clin Infect Dis , vol.47 , pp. 1260-1269
    • Liu, C.H.1    Liu, C.J.2    Lin, C.L.3
  • 53
    • 80054846451 scopus 로고    scopus 로고
    • Improved responses to pegylated interferon alfa-2b and ribavirin by individualizing treatment for 24-72 weeks
    • doi: 10.1053/j.gastro.2011.07.019
    • Sarrazin C, Schwendy S, Moller B, et al. Improved responses to pegylated interferon alfa-2b and ribavirin by individualizing treatment for 24-72 weeks. Gastroenterology 2011; doi: 10.1053/j.gastro.2011.07.019
    • (2011) Gastroenterology
    • Sarrazin, C.1    Schwendy, S.2    Moller, B.3
  • 54
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Fried MW, Shiffman ML, Reddy KR, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002; 347:975-982.
    • (2002) N Engl J Med , vol.347 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 55
    • 1542378867 scopus 로고    scopus 로고
    • Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
    • Hadziyannis SJ, Sette H, Jr., Morgan TR, et al. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004; 140:346-355.
    • (2004) Ann Intern Med , vol.140 , pp. 346-355
    • Hadziyannis, S.J.1    Sette Jr., H.2    Morgan, T.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.