A comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy

Journal of the International Association of Physicians in AIDS Care

Volumn 10, Issue 6, 2011, Pages 351-356

  Signorini, Dario José Hart Pontes ^a   Netto, Ana Maria Schmidt De Oliveira ^b   Gabbay, Sergio ^b   Monteiro, Michelle Carreira Miranda ^a   Signorini, Dario Hart ^a   Andrade, Marion De Fátima Castro De ^a   Bastos, Francisco I ^c   Codeço, Cláudia Torres ^c  

^a HOSPITAL UNIVERSITÁRIO GAFFRÉE E GUINLE   (Brazil)

^b Instituto Brasileiro de Ultra Sonografia   (Brazil)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

anti HIV agents; HIV associated lipodystrophy syndrome; logistic models; ROC curve; sensitivity and specificity; ultrasonography

Indexed keywords

ABDOMEN; ADULT; ARM; ARTICLE; BODY FAT; CLINICAL ASSESSMENT; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; ECHOGRAPHY; FACE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMAGING; KAPPA STATISTICS; LIPODYSTROPHY; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PREDICTIVE VALUE; PRIORITY JOURNAL; QUESTIONNAIRE; SENSITIVITY AND SPECIFICITY; ADIPOSE TISSUE; HIV ASSOCIATED LIPODYSTROPHY;

ADIPOSE TISSUE; HIV INFECTIONS; HIV-ASSOCIATED LIPODYSTROPHY SYNDROME; HUMANS; LIPODYSTROPHY; SURVEYS AND QUESTIONNAIRES;

EID: 83455162696     PISSN: 15451097     EISSN: 15570886     Source Type: Journal    
DOI: 10.1177/1545109711399660     Document Type: Article

References (31)

1. Moreno S, Miralles C, Negredo E, et al. Disorders of body fat distribution in HIV-1-infected patients. AIDS Rev. 2009 ; 11 (3). 126-134
2. Santos CP, Felipe YX, Braga PE, Ramos D, Lima RO, Segurado AC. Self-perception of body changes in persons living with HIV/AIDS: prevalence and associated factors. AIDS (Lond, Eng). 2005 ; 19 (suppl 4). S14 - S21
3. Monnerat BZ, Cerutti Junior C, Canicali SC, Motta TR. Clinical and biochemical evaluation of HIV-related lipodystrophy in an ambulatory population from the Hospital Universitario Cassiano Antonio de Morais, Vitoria, ES, Brazil. Braz J Infect Dis. 2008 ; 12 (4). 364-368
4. Nunn AS, Fonseca EM, Bastos FI, Gruskin S, Salomon JA. Evolution of antiretroviral drug costs in Brazil in the context of free and universal access to AIDS treatment. PLoS Med. 2007 ; 4 (11). e305
5. Nunn AS, da Fonseca EM, Bastos FI, Gruskin S. AIDS treatment in Brazil: impacts and challenges. Health Aff (Millwood). 2009 ; 28 (4). 1103-1113
6. Viraben R, Aquilina C. Indinavir-associated lipodystrophy. AIDS (Lond, Engl). 1998 ; 12 (6). F37 - F39
7. Galli M, Cozzi-Lepri A, Ridolfo AL, et al. Incidence of adipose tissue alterations in first-line antiretroviral therapy: the LipoICoNa Study. Arch Intern Med. 2002 ; 162 (22). 2621-2628 (Pubitemid 35453502)
8. Weaver TW, Kushi LH, McGovern PG, et al. Validation study of self-reported measures of fat distribution. Int J Obes Relat Metab Disord. 1996 ; 20 (7). 644-650 (Pubitemid 26237723)
9. Engelson ES, Kotler DP, Tan Y, et al. Fat distribution in HIV-infected patients reporting truncal enlargement quantified by whole-body magnetic resonance imaging. Am J Clin Nutr. 1999 ; 69 (6). 1162-1169 (Pubitemid 29252048)
10. Lichtenstein KA, Ward DJ, Moorman AC, et al. Clinical assessment of HIV-associated lipodystrophy in an ambulatory population. AIDS (Lond, Eng). 2001 ; 15 (11). 1389-1398 (Pubitemid 32662290)
11. Grunfeld C Program and Abstracts of the XIV International AIDS Conference. Barcelona, Spain: ; 2002 :
12. Bacchetti P, Gripshover B, Grunfeld C, et al. Fat distribution in men with HIV infection. J Acquir Immune Defic Syndr. 2005 ; 40 (2). 121-131 (Pubitemid 41395709)
13. Tien PC, Benson C, Zolopa AR, Sidney S, Osmond D, Grunfeld C. The study of fat redistribution and metabolic change in HIV infection (FRAM): methods, design, and sample characteristics. Am J Epidemiol. 2006 ; 163 (9). 860-869
14. Martinez E, Bianchi L, Garcia-Viejo MA, Bru C, Gatell JM. Sonographic assessment of regional fat in HIV-1-infected people. Lancet. 2000 ; 356 (9239). 1412-1413
15. Asensi V, Martin-Roces E, Collazos J, et al. Association between physical and echographic fat thickness assessments and a lipodystrophy grading scale in lipodystrophic HIV patients: practical implications. AIDS Res Hum Retroviruses. 2006 ; 22 (9). 830-836 (Pubitemid 44757157)
16. Guimaraes MM, de Oliveira AR., Penido MG, et al. Ultrasonographic measurement of intra-abdominal fat thickness in HIV-infected patients treated or not with antiretroviral drugs and its correlation to lipid and glycemic profiles. Ann Nutr Metab. 2007 ; 51 (1). 35-41 (Pubitemid 46633188)
17. Padilla S, Gallego JA, Masia M, Ardoy F, Hernandez I, Gutierrez F. Ultrasonography and anthropometry for measuring regional body fat in HIV-infected patients. Curr HIV Res. 2007 ; 5 (5). 459-466
18. Grima PF, Chiavaroli R, Grima P. Ultrasonographic assessment of lipodystrophy in HIV-1-infected patients. Radiol Med. 2009 ; 114 (1). 141-151
19. Radominski RB, Vezozzo DP, Cerri GG, Halpern A. O uso da ultra-sonografia na avaliação da distribuição de gordura abdominal. Arquivos Brasileiros de Endocrinologia Metabologia. 2000 ; 44 (1). 5-12
20. R: A Language and Environment for Statistical Computing. 2.9.1 ed.Vienna, Austria: R Foundation for Statistical Computing; 2009. Vienna, Austria: R Foundation for Statistical Computing ; 2009 :
21. Fox J An R and S-Plus Companion to Applied Regression. 2002 :192-201. Publications S, ed. Thousand Oaks, CA: ; 2002: 192-201.
22. AIDS epidemic update 2009. 2009http://data.unaids.org/pub/Report/2009/ JC1700-Epi-Update-2009-en.pdf. Accessed May 16, 2010
23. Effect of sociodemographic, clinical-prophylactic and therapeutic procedures on survival of AIDS patients assisted in a Brazilian outpatient clinic. 2005. http://www.scielo.br/scielo.php?script=sci-arttext&pid=S1415- 790X2005000300007&lng=pt&nrm=iso. Accessed May 21, 2010
24. Villarroya F, Domingo P, Giralt M. Drug-induced lipotoxicity: lipodystrophy associated with HIV-1 infection and antiretroviral treatment. Biochim Biophys Acta. 2010 ; 1801 (3). 392-399
25. Chesney MA. Factors affecting adherence to antiretroviral therapy. Clin Infect Dis. 2000 ; 30 (suppl 2). S171 - S176
26. Carr A, Emery S, Law M, Puls R, Lundgren JD, Powderly WG. An objective case definition of lipodystrophy in HIV-infected adults: a case-control study. Lancet. 2003 ; 361 (9359). 726-735 (Pubitemid 36293626)
27. Martinez E, Milinkovic A, Bianchi L, Gatell JM. Considerations about the value of sonography for the measurement of regional body fat. AIDS (Lond, Engl). 2006 ; 20 (17). 465-466
28. Carr A, Samaras K, Thorisdottir A, Kaufmann GR, Chisholm DJ, Cooper DA. Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort study. Lancet. 1999 ; 353 (9170). 2093-2099 (Pubitemid 29278477)
29. Asensi V, Martin-Roces E, Carton J, et al. Perirenal fat diameter measured by echography could be an early predictor of lipodystrophy in HIV type 1- infected patients receiving highly active antiretroviral therapy. Clin Infect Dis. 2004 ; 39 (2). 240-247 (Pubitemid 38971496)
30. Gulizia R, Vercelli A, Gervasoni C, et al. Controversy concerning role of ultrasonographic lipoatrophy assessments in HIV patients. AIDS (Lond, Engl). 2006 ; 20 (5). 789-790 (Pubitemid 43884314)
31. Carey D, Wand H, Martin A, et al. Evaluation of ultrasound for assessing facial lipoatrophy in a randomized, placebo-controlled trial. AIDS (Lond, Engl). 2005 ; 19 (12). 1325-1327 (Pubitemid 41224904)