Urinary basic fibroblast growth factor in bladder cancer patients: Histopathological correlation and clinical potential

Urologia Internationalis

Volumn 73, Issue 2, 2004, Pages 173-177

  Gravas, S ^a   Bosinakou, I ^b   Kehayasa, P ^a   Giannopoulos, A ^c  

^a HYGEIA HOSPITAL   (Greece)

^b HIPPOKRATION HOSPITAL   (Greece)

^c UNIVERSITY OF ATHENS   (Greece)

Author keywords

Angiogenesis; Basic fibroblast growth factor; Benign prostatic hyperplasia; Bladder cancer

Indexed keywords

ANGIOGENIC FACTOR; BASIC FIBROBLAST GROWTH FACTOR; CREATININE;

ADULT; AGED; ARTICLE; BLADDER CANCER; CANCER GRADING; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE URINE LEVEL; CYSTOSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; MALE; PRIORITY JOURNAL; PROSTATE HYPERTROPHY; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; STATISTICAL SIGNIFICANCE; URINALYSIS;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; FIBROBLAST GROWTH FACTOR 2; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; PROSPECTIVE STUDIES; URINARY BLADDER NEOPLASMS;

EID: 8344279695     PISSN: 00421138     EISSN: None     Source Type: Journal    
DOI: 10.1159/000079700     Document Type: Article

References (21)

1. Folkman J: What is the evidence that tumours are angiogenesis dependent? N Engl J Med 1990;82:4-6.
2. Campbell SC: Advances in agiogenesis research: Relevance to urological oncology. J Urol 1997;158:1663-1674.
3. Papetti M, Herman IM: Mechanisms of normal and tumor-derived angiogenesis. Am J Physiol Cell Physiol 2002;282:947-970.
4. Rifkin DB, Moscatelli D: Recent developments in the cell biology of basic fibroblast growth factor. J Cell Biol 1989;109:1-6.
5. Steiner MS: Role of peptide growth factors in the prostate: A review. Urology 1993;42:99-110.
6. Begun FP, Story MT, Hopp KA, Shapiro E, Lawson RK: Regional concentration of basic fibroblast growth factor in normal and benign hyperplastic human prostates. J Urol, 1995;153:839-843.
7. Muller W, Lee F, Dickson C, Peters G, Pattengale P, Leder P: The int-2 gene product acts as an epithelial growth factor in transgenic mice. EMBO J 1990;9:907-913.
8. Nguyen M, Watanabe H, Budson AE, Richie JP, Folkman J: Elevated levels of the angiogenic peptide basic fibroblast growth factor in urine of bladder cancer patients. J Natl Cancer Inst 1993;85:241-242.
9. O' Brien TS, Smith K, Cranston D, Fuggle S, Bicknell R, Harris AL: Urinary basic fibroblast growth factor in patients with bladder cancer and benign prostatic hypertrophy. Br J Urol 1995;76:311-314.
10. Harris Al: Antiangiogenesis for cancer therapy. Lancet 1997;349(suppl II):13-15.
11. Jones A, Fujiyama C: Angiogenesis in urological malignancy: Prognostic indicator and therapeutic target. BJU Int 1999;83:535-556.
12. Stein JP, Grossfeld GD, Ginsberg DA, et al: Prognostic markers in bladder cancer: A contemporary review of the literature. J Urol 1998;160:645-659.
13. Chopin DK, Caruelle JP, Colombel M, Palcy S, Ravery V, Caruelle D, Abbou CC, Barritault D: Increased immunodetection of acidic fibroblast growth factor in bladder cancer, detectable in urine. J Urol 1993;150:1126-1130.
14. Jones A, Crew J: Vascular endothelial growth factor and its correlation with superficial bladder cancer recurrence rates and stage progression. Urol Clins N Am 2000;27:191-197.
15. Bernardini S, Fauconnet S, Chabannes E, Henry PC, Adessi G, Bittard H: Serum levels of vascular endothelial growth factor as a prognostic factor in bladder cancer. J Urol 2001;166:1275-1279.
16. Lokeshwar VB, Obek C, Pham HT, Wei D, Young MJ, Duncan RC, Soloway MS, Block NL: Urinary hyaluronic acid and hyaluronidase: Markers for bladder cancer detection and evaluation of grade. J Urol 2000;163:348-356.
17. Miyake H, Hara I, Yamanaka K, Gohji K, Arakawa S, Kamidono S: Increased angiogenin expression in the tumor tissue and serum of urothelial carcinoma patients is related to disease progression and recurrence. Cancer 1999;86:316-324.
18. O' Brien TS, Cranston D, Fuggle S, Bicknell R, Harris AL: Two mechanisms of basic fibroblast growth factor-induced angiogenesis in bladder cancer. Cancer Res 1997;57:136-140.
19. Weingartner K, Ben-Sasson SA, Stewart R, Ritchie JP, Riemiller H, Folkman J: Endothelial cell proliferation activity in benign prostatic hyperplasia and prostate cancer. J Urol 1998;159:465-470.
20. Dinney CPN, Bielenberg DR, Perrotte P, Reich R, Eve BY, Bucana CD, Fidler IJ: Inhibition of basic fibroblast growth factor expression, angiogenesis, and growth of human bladder carcinoma in mice by systemic interferon-α administration. Cancer Res 1998;58:808-814.
21. Giannopoulos A, Adamakis I, Evangelou K, Giannopoulou M, Zacharatos P, Retalis G, Constantinidis C, Gorgoulis VG: Interferonalpha reduces neo-microvascular density in the adjacent to the tumor normal urothelium after transurethral resection of superficial bladder carcinoma. Onkologie, in press.