Asymmetric desymmetrization based on an intramolecular haloetherification: A highly effective and recyclable chiral nonracemic auxiliary, 2-exo-methyl-3-endo-phenyl-5-norbornene-2-carboxaldehyde, for meso-1,3- and meso-1,4-diols

Chemistry - A European Journal

Volumn 10, Issue 21, 2004, Pages 5386-5397

  Fujioka, Hiromichi ^a   Fujita, Tetsuya ^a   Kotoku, Naoyuki ^a   Ohba, Yusuke ^a   Nagatomi, Yasushi ^a   Hiramatsu, Atsushi ^a   Kita, Yasuyuki ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Asymmetric synthesis; Chiral auxiliaries; Desymmetrization; Diols; Norbornene

Indexed keywords

ALCOHOLS; ALDEHYDES; CRYSTALLIZATION; ETHERS; HYDROLYSIS;

ACID HYDROLYSIS; ENANTIOSELECTIVITY; INTRAMOLECULAR BROMOETHERIFICATION;

DERIVATIVES;

1,3 DIOL DERIVATIVE; 1,4 DIOL DERIVATIVE; 2 METHYL 3 PHENYL 5 NORBORNENE 2 CARBOXALDEHYDE; ALCOHOL DERIVATIVE; NORBORNENE DERIVATIVE; UNCLASSIFIED DRUG;

ACETALIZATION; ARTICLE; BROMOETHERIFICATION; CHEMICAL REACTION; CHIRALITY; CRYSTALLIZATION; DESYMMETRIZATION; DIASTEREOISOMER; ENANTIOSELECTIVITY; ETHERIFICATION; HALOETHERIFICATION; HYDROLYSIS; MOLECULAR STABILITY; OPTICAL ROTATION; PROTECTION REACTION; RACEMIC MIXTURE; RECYCLING; SYNTHESIS;

GLYCOLS; ISOMERISM; MOLECULAR STRUCTURE; NORBORNANES; STEREOISOMERISM;

EID: 8344270145     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/chem.200400444     Document Type: Article

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