Influences of gender and region on responses to 5-HT in the rat small intestine

Pharmacology

Volumn 72, Issue 4, 2004, Pages 220-224

  Liu, H ^a   Irving, H R ^a   Tan, Y Y ^a   Meng, L ^a   Chetty, N ^a   Coupar, I M ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

5 HT; 5 HT7 mRNA; 5 HT7 receptor; Rat small intestine; Serotonin

Indexed keywords

ACETYLCHOLINE; MESSENGER RNA; SEROTONIN; SEROTONIN RECEPTOR;

ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; ILEUM; INTESTINE CONTRACTION; INTESTINE MUSCLE; JEJUNUM; MALE; MUSCLE TISSUE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR GENE; SEX DIFFERENCE;

ACETYLCHOLINE; ANIMALS; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROUS CYCLE; FEMALE; ILEUM; INTESTINE, SMALL; JEJUNUM; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; ONDANSETRON; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEROTONIN; SEROTONIN ANTAGONISTS; SEX CHARACTERISTICS; VASODILATOR AGENTS;

EID: 8344223040     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000080376     Document Type: Article

References (15)

1. 7 receptors: Current knowledge and future prospects. Trends Pharmacol Sci 2000;21:70-77.
2. 3 receptor mediating contraction of rat isolated jejunum. Eur J Pharmacol 1996;312:215-225.
3. Carter D, Champney M, Hwang B, Eglen RM: Characterization of a postjunctional 5-HT receptor mediating relaxation of guinea-pig isolated ileum. Eur J Pharmacol 1995;280:243-250.
4. 7 receptors mediating relaxation of human colonic circular smooth muscle. Br J Pharmacol 1999;128:849-852.
5. Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PP: International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol Rev 1994;46:157-203.
6. Hofmann F: The molecular basis of second messenger systems for regulation of smooth muscle contractility. J Hypertens Suppl 19853(suppl 3):3-8.
7. McDaniel NL, Rembold CM, Murphy RA: Cyclic nucleotide dependent relaxation in vascular smooth muscle. Can J Physiol Pharmacol 1994;72:1380-1385.
8. 7 sites in rat brain and guinea-pig ileum but not rat jejunum. Br J Pharmacol 1999;126:179-188.
9. 7 receptor isoforms in the rat digestive tract. Life Sci 2001;69:2467-2475.
10. Liu H, Coupar IM, Irving HR: Effects of some antidepressant drugs on tryptaminergic responses of the rat jejunum. Pharmacology 2003;69:88-92.
11. 7) receptor isoforms in human and rat produced by alternative splicing: Species differences due to altered intron-exon organization. J Neurochem 1997;68:1372-1381.
12. Feniuk W, Humphrey PP, Watts AD: 5-Hydroxytryptamine-induced relaxation of isolated mammalian smooth muscle. Eur J Pharmacol 1983;96:71-78.
13. 125I]LSD binding. Eur J Pharmacol 1986;129:139-145.
14. 2 receptors mediating contraction. Neurogastroenterol Motil 1997;9:231-237.
15. Bennett A, Houghton J: Gradients of monoamine levels in guinea-pig isolated ileum. Br J Pharmacol 1976;57:443-444.