-
1
-
-
0037061874
-
Review of advances in pressure ulcer management since 1992
-
Dealey C. Review of advances in pressure ulcer management since 1992. Br J Nurs. 2002; 11:486-90.
-
(2002)
Br J Nurs
, vol.11
, pp. 486-490
-
-
Dealey, C.1
-
2
-
-
0030094678
-
The costeffectiveness of interventions for preventing pressure ulcers
-
Xakellis GC, Frantz RA. The costeffectiveness of interventions for preventing pressure ulcers. J Am Board Fam Pract. 1996; 9(2):79-85.
-
(1996)
J Am Board Fam Pract
, vol.9
, Issue.2
, pp. 79-85
-
-
Xakellis, G.C.1
Frantz, R.A.2
-
3
-
-
1442351776
-
Unexpected economics of ulcer care protocols
-
Kerstein MD. Unexpected economics of ulcer care protocols. South Med J. 2004; 97:135-6.
-
(2004)
South Med J
, vol.97
, pp. 135-136
-
-
Kerstein, M.D.1
-
4
-
-
0030629043
-
Outcomes in clinical practice: Pressure ulcer prevalence and incidence studies
-
Gallagher S. Outcomes in clinical practice: pressure ulcer prevalence and incidence studies. Ostomy Wound Manag. 1997; 43:28-32,34-5,38.
-
(1997)
Ostomy Wound Manag
, vol.43
, pp. 28-32
-
-
Gallagher, S.1
-
5
-
-
0033430334
-
Skin anatomy, physiology, and pathophysiology
-
Wysocki AB. Skin anatomy, physiology, and pathophysiology. Nurs Clin North Am. 1999; 34:777-97.
-
(1999)
Nurs Clin North Am
, vol.34
, pp. 777-797
-
-
Wysocki, A.B.1
-
7
-
-
0029261853
-
A review of the skin and its appendages
-
Wysocki AB. A review of the skin and its appendages. Adv Wound Care. 1995; 8(2, part 1):53-4,56-62,64.
-
(1995)
Adv Wound Care
, vol.8
, Issue.2 PART 1
, pp. 53-54
-
-
Wysocki, A.B.1
-
9
-
-
0001413484
-
Interactions of cytokines, growth factors, and proteases in acute and chronic wounds
-
Mast BA, Schultz GS. Interactions of cytokines, growth factors, and proteases in acute and chronic wounds. Wound Repair Regen. 1996; 4:411-20.
-
(1996)
Wound Repair Regen
, vol.4
, pp. 411-420
-
-
Mast, B.A.1
Schultz, G.S.2
-
10
-
-
1642567557
-
Growth factors and chronic wound healing: Past, present, and future
-
Goldman R. Growth factors and chronic wound healing: past, present, and future. Adv Skin Wound Care. 2004; 17(1):24-35.
-
(2004)
Adv Skin Wound Care
, vol.17
, Issue.1
, pp. 24-35
-
-
Goldman, R.1
-
11
-
-
0028598011
-
Role of the extracellular matrix in the degradation of connective tissue
-
Mauch C, Kreig T, Bauer RA. Role of the extracellular matrix in the degradation of connective tissue. Arch Dermatol Res. 1994; 287:107-14.
-
(1994)
Arch Dermatol Res
, vol.287
, pp. 107-114
-
-
Mauch, C.1
Kreig, T.2
Bauer, R.A.3
-
12
-
-
0025600345
-
Basic principles of wound healing
-
Hunt TK. Basic principles of wound healing. J Trauma. 1990; 30:122s-8s.
-
(1990)
J Trauma
, vol.30
-
-
Hunt, T.K.1
-
13
-
-
0028440816
-
National pressure ulcer prevalence survey
-
Meehan M. National pressure ulcer prevalence survey. Adv Wound Care. 1994; 7(3):27-30,34,36-8.
-
(1994)
Adv Wound Care
, vol.7
, Issue.3
, pp. 27-30
-
-
Meehan, M.1
-
14
-
-
0034862568
-
Age-related changes in wound healing
-
Thomas DR. Age-related changes in wound healing. Drugs Aging. 2001; 18: 607-20.
-
(2001)
Drugs Aging
, vol.18
, pp. 607-620
-
-
Thomas, D.R.1
-
15
-
-
0029160829
-
Prevention and treatment of pressure sores
-
Patterson JA, Bennett RG. Prevention and treatment of pressure sores. J Am Geriatr Soc. 1995; 43:919-27.
-
(1995)
J Am Geriatr Soc
, vol.43
, pp. 919-927
-
-
Patterson, J.A.1
Bennett, R.G.2
-
16
-
-
0036092369
-
Pressure ulcer development in the operating room
-
Schouchoff B. Pressure ulcer development in the operating room. Crit Care Nurs Q. 2002; 25(1):76-82.
-
(2002)
Crit Care Nurs Q
, vol.25
, Issue.1
, pp. 76-82
-
-
Schouchoff, B.1
-
17
-
-
0037342982
-
Incidence and costs of acute medical conditions in long-stay incontinent nursing home residents
-
Alessi CA, Ouslander JG, Maldague S et al. Incidence and costs of acute medical conditions in long-stay incontinent nursing home residents. J Am Med Dir Assoc. 2003; 4:S5-18.
-
(2003)
J Am Med Dir Assoc
, vol.4
-
-
Alessi, C.A.1
Ouslander, J.G.2
Maldague, S.3
-
18
-
-
0024981006
-
Pressure ulcers among the elderly
-
Allman RM. Pressure ulcers among the elderly. N Engl J Med. 1989; 320:850-3.
-
(1989)
N Engl J Med
, vol.320
, pp. 850-853
-
-
Allman, R.M.1
-
19
-
-
0028948764
-
Extravasation of macromolecules and possible trapping of transforming growth factor-beta in venous ulceration
-
Higley HR, Ksander GA, Gerhardt CO et al. Extravasation of macromolecules and possible trapping of transforming growth factor-beta in venous ulceration. Br J Dermatol. 1995; 132:79-85.
-
(1995)
Br J Dermatol
, vol.132
, pp. 79-85
-
-
Higley, H.R.1
Ksander, G.A.2
Gerhardt, C.O.3
-
20
-
-
8344231904
-
-
National Pressure Ulcer Advisory Panel. Staging report. www.npuap.org/ positn6.html (accessed 2004 Feb 17).
-
Staging Report
-
-
-
21
-
-
0027529473
-
The importance of dietary protein in healing pressure ulcers
-
Breslow RA, Hallfrisch J, Guy DG et al. The importance of dietary protein in healing pressure ulcers. J Am Geriatr Soc. 1993; 41:357-62.
-
(1993)
J Am Geriatr Soc
, vol.41
, pp. 357-362
-
-
Breslow, R.A.1
Hallfrisch, J.2
Guy, D.G.3
-
22
-
-
0000602177
-
The effect of a high protein formulation (Replete) on decubitus ulcer healing in long term tube fed institutionalized patients
-
Chernoff RS, Milton KY, Lipschitz DA. The effect of a high protein formulation (Replete) on decubitus ulcer healing in long term tube fed institutionalized patients. J Am Diet Assoc. 1990; 90:A-130.
-
(1990)
J Am Diet Assoc
, vol.90
-
-
Chernoff, R.S.1
Milton, K.Y.2
Lipschitz, D.A.3
-
23
-
-
0022518129
-
Correlation of pressure sores and nutritional status
-
Pinchcofsky-Devin GD, Kaminski MV. Correlation of pressure sores and nutritional status. J Am Geriatr Soc. 1996; 34: 435-40.
-
(1996)
J Am Geriatr Soc
, vol.34
, pp. 435-440
-
-
Pinchcofsky-Devin, G.D.1
Kaminski, M.V.2
-
24
-
-
0026686336
-
A prospective study of pressure sore risk among institutionalized elderly
-
Bergstrom N, Braden B. A prospective study of pressure sore risk among institutionalized elderly. J Am Geriatr Soc. 1992; 40:747-58.
-
(1992)
J Am Geriatr Soc
, vol.40
, pp. 747-758
-
-
Bergstrom, N.1
Braden, B.2
-
25
-
-
0024430025
-
Risk factors for pressure sores. A comparison of cross-sectional and cohort-derived data
-
Berlowitz DR, Wilking SV. Risk factors for pressure sores. A comparison of cross-sectional and cohort-derived data. J Am Geriatr Soc. 1989; 37:1043-50.
-
(1989)
J Am Geriatr Soc
, vol.37
, pp. 1043-1050
-
-
Berlowitz, D.R.1
Wilking, S.V.2
-
26
-
-
0026771084
-
Prolonged tube feeding in long-term care: Nutritional status and clinical outcomes
-
Henderson CT, Trumbore LS, Mobarhan S et al. Prolonged tube feeding in long-term care: nutritional status and clinical outcomes. J Am Coll Nutr. 1992; 11:309-25.
-
(1992)
J Am Coll Nutr
, vol.11
, pp. 309-325
-
-
Henderson, C.T.1
Trumbore, L.S.2
Mobarhan, S.3
-
27
-
-
0029620317
-
Randomized clinical trial of ascorbic acid in the treatment of pressure ulcers
-
Ter Riet G, Kessels AH, Knipschild PG. Randomized clinical trial of ascorbic acid in the treatment of pressure ulcers. J Clin Epidemiol. 1995; 48:1453-60.
-
(1995)
J Clin Epidemiol
, vol.48
, pp. 1453-1460
-
-
Ter Riet, G.1
Kessels, A.H.2
Knipschild, P.G.3
-
28
-
-
0020422303
-
Zinc nutriture in the elderly in relation to taste acuity, immune response, and wound healing
-
Sandstead HH, Henriksen LK, Greger JL et al. Zinc nutriture in the elderly in relation to taste acuity, immune response, and wound healing. Am J Clin Nut. 1982; 36:1046-59.
-
(1982)
Am J Clin Nut
, vol.36
, pp. 1046-1059
-
-
Sandstead, H.H.1
Henriksen, L.K.2
Greger, J.L.3
-
29
-
-
8344289996
-
How to choose the right treatment and dressing for the wound
-
Calianno C. How to choose the right treatment and dressing for the wound. Nurs Manag. 2003; 34(1):6-14.
-
(2003)
Nurs Manag
, vol.34
, Issue.1
, pp. 6-14
-
-
Calianno, C.1
-
30
-
-
0022480579
-
A wound model for ischemic ulcers in the guinea pig
-
Constantine BE, Bolton LL. A wound model for ischemic ulcers in the guinea pig. Arch Dermatol Res. 1986; 278:429-31.
-
(1986)
Arch Dermatol Res
, vol.278
, pp. 429-431
-
-
Constantine, B.E.1
Bolton, L.L.2
-
31
-
-
0034885972
-
Prevention and treatment of pressure ulcers: What works? What doesn't
-
Thomas DR. Prevention and treatment of pressure ulcers: what works? What doesn't. Cleve Clin J Med. 2001; 68:704-22.
-
(2001)
Cleve Clin J Med
, vol.68
, pp. 704-722
-
-
Thomas, D.R.1
-
35
-
-
0030237996
-
Back to basics: Choosing the correct wound dressing
-
Walker D. Back to basics: choosing the correct wound dressing. Am J Nurs. 1996; 96(9):35-9.
-
(1996)
Am J Nurs
, vol.96
, Issue.9
, pp. 35-39
-
-
Walker, D.1
-
37
-
-
0142024064
-
Topical treatment of pressure ulcers with nerve growth factor: A randomized clinical trial
-
Landi F, Aloe L, Russo A et al. Topical treatment of pressure ulcers with nerve growth factor: a randomized clinical trial. Ann Intern Med. 2003; 139:635-41.
-
(2003)
Ann Intern Med
, vol.139
, pp. 635-641
-
-
Landi, F.1
Aloe, L.2
Russo, A.3
-
38
-
-
0022459815
-
Multiple biological activities of human recombinant interleukin 1
-
Dinarello CA, Cannon JG, Mier JW et al. Multiple biological activities of human recombinant interleukin 1. J Clin Invest. 1986; 77:1734-9.
-
(1986)
J Clin Invest
, vol.77
, pp. 1734-1739
-
-
Dinarello, C.A.1
Cannon, J.G.2
Mier, J.W.3
-
39
-
-
0021318477
-
Interleukin-1
-
Dinarello CA. Interleukin-1. Rev Infect Dis. 1984; 6(1):51-95.
-
(1984)
Rev Infect Dis
, vol.6
, Issue.1
, pp. 51-95
-
-
Dinarello, C.A.1
-
40
-
-
0023878440
-
Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors
-
Kaushansky K, Lin N, Adamson JW. Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. J Clin Invest. 1988; 81:92-7.
-
(1988)
J Clin Invest
, vol.81
, pp. 92-97
-
-
Kaushansky, K.1
Lin, N.2
Adamson, J.W.3
-
41
-
-
84989104603
-
Safety and effect of topical recombinant human interleukin-1β in the management of pressure sores
-
Robson MC, Abdullah A, Burns BF et al. Safety and effect of topical recombinant human interleukin-1β in the management of pressure sores. Wound Rep Regen. 1994; 2:177-81.
-
(1994)
Wound Rep Regen
, vol.2
, pp. 177-181
-
-
Robson, M.C.1
Abdullah, A.2
Burns, B.F.3
-
42
-
-
0023335817
-
Structural characterization and biological functions of fibroblast growth factor
-
Gospodarowicz D, Ferrara N, Schweigerer et al. Structural characterization and biological functions of fibroblast growth factor. Endocr Rev. 1987; 8(2):95-114.
-
(1987)
Endocr Rev
, vol.8
, Issue.2
, pp. 95-114
-
-
Gospodarowicz, D.1
Ferrara, N.2
Schweigerer3
-
43
-
-
0024370274
-
Recent developments in the cell biology of basic fibroblast growth factor
-
Rifkin DB, Moscatelli D. Recent developments in the cell biology of basic fibroblast growth factor. J Cell Biol. 1989; 109:1-6.
-
(1989)
J Cell Biol
, vol.109
, pp. 1-6
-
-
Rifkin, D.B.1
Moscatelli, D.2
-
44
-
-
0025690370
-
Basic fibroblast growth factor stimulation of epidermal wound healing in pigs
-
Hebda PA, Klingbeil CK, Abraham JA et al. Basic fibroblast growth factor stimulation of epidermal wound healing in pigs. J Invest Dermatol. 1990; 95:626-31.
-
(1990)
J Invest Dermatol
, vol.95
, pp. 626-631
-
-
Hebda, P.A.1
Klingbeil, C.K.2
Abraham, J.A.3
-
45
-
-
0026409682
-
Pre-clinical wound-healing studies with recombinant human basic fibroblast growth factor
-
Fiddes JC, Hebda PA, Hayward P. Pre-clinical wound-healing studies with recombinant human basic fibroblast growth factor. Ann N Y Acad Sci. 1991; 638:316-28.
-
(1991)
Ann N Y Acad Sci
, vol.638
, pp. 316-328
-
-
Fiddes, J.C.1
Hebda, P.A.2
Hayward, P.3
-
46
-
-
0026786815
-
The safety and effect of topically applied recombinant basic fibroblast growth factor on the healing of chronic pressure sores
-
Robson M, Phillips LG, Lawrence WT. The safety and effect of topically applied recombinant basic fibroblast growth factor on the healing of chronic pressure sores. Ann Surg. 1992; 216:401-6.
-
(1992)
Ann Surg
, vol.216
, pp. 401-406
-
-
Robson, M.1
Phillips, L.G.2
Lawrence, W.T.3
-
47
-
-
0034031419
-
Sequential cytokine therapy for pressure ulcers: Clinical and mechanistic response
-
Robson MC, Hill DP, Smith PD. Sequential cytokine therapy for pressure ulcers: clinical and mechanistic response. Ann Surg. 2000; 231:600-11.
-
(2000)
Ann Surg
, vol.231
, pp. 600-611
-
-
Robson, M.C.1
Hill, D.P.2
Smith, P.D.3
-
48
-
-
0142087837
-
The promise of topical growth factors in healing pressure ulcers
-
Editorial
-
Thomas DR. The promise of topical growth factors in healing pressure ulcers. Ann Intern Med. 2003; 139:694-5. Editorial.
-
(2003)
Ann Intern Med
, vol.139
, pp. 694-695
-
-
Thomas, D.R.1
-
49
-
-
0032472835
-
Role of nerve growth factor in cutaneous wound healing: Accelerating effects in normal and healing-impaired diabetic mice
-
Matsuda H, Koyama H, Sato H et al. Role of nerve growth factor in cutaneous wound healing: accelerating effects in normal and healing-impaired diabetic mice. J Exp Med. 1998; 187:297-306.
-
(1998)
J Exp Med
, vol.187
, pp. 297-306
-
-
Matsuda, H.1
Koyama, H.2
Sato, H.3
-
50
-
-
0019205937
-
Nerve growth factor: Acceleration of the rate of wound healing in mice
-
Li AK, Koroly AJ, Schattenkerk ME. Nerve growth factor: acceleration of the rate of wound healing in mice. Proc Natl Acad Sci USA. 1980; 77:4379-81.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 4379-4381
-
-
Li, A.K.1
Koroly, A.J.2
Schattenkerk, M.E.3
-
51
-
-
0026595966
-
Platelet-derived growth factor BB for the treatment of chronic pressure ulcers
-
Robson MC, Phillips LG. Platelet-derived growth factor BB for the treatment of chronic pressure ulcers. Lancet. 1992; 339:23-5.
-
(1992)
Lancet
, vol.339
, pp. 23-25
-
-
Robson, M.C.1
Phillips, L.G.2
-
52
-
-
0025894052
-
Role of platelet-derived growth factor in wound healing
-
Pierce GF, Mustoe TA, Altrock BW et al. Role of platelet-derived growth factor in wound healing. J Cell Biol. 1991; 45:319-26.
-
(1991)
J Cell Biol
, vol.45
, pp. 319-326
-
-
Pierce, G.F.1
Mustoe, T.A.2
Altrock, B.W.3
-
53
-
-
0020046560
-
Chemotaxis of monocytes and neutrophils to platelet-derived growth factor
-
Deuel TF, Senior RM, Huang JS et al. Chemotaxis of monocytes and neutrophils to platelet-derived growth factor. J Clin Invest. 1982; 69:1046-9.
-
(1982)
J Clin Invest
, vol.69
, pp. 1046-1049
-
-
Deuel, T.F.1
Senior, R.M.2
Huang, J.S.3
-
54
-
-
0021830028
-
Platelet-derived growth factor promotes human peripheral monocyte activation
-
Tzeng DY, Deuel TF, Huang JS et al. Platelet-derived growth factor promotes human peripheral monocyte activation. Blood. 1985; 66:179-83.
-
(1985)
Blood
, vol.66
, pp. 179-183
-
-
Tzeng, D.Y.1
Deuel, T.F.2
Huang, J.S.3
-
55
-
-
0028069703
-
A Phase II study to evaluate recombinant platelet-derived growth factor-BB in the treatment of stage 3 and 4 pressure ulcers
-
Mustoe TA, Cutler NR, Allman RM et al. A Phase II study to evaluate recombinant platelet-derived growth factor-BB in the treatment of stage 3 and 4 pressure ulcers. Arch Surg. 1994; 129:213-9.
-
(1994)
Arch Surg
, vol.129
, pp. 213-219
-
-
Mustoe, T.A.1
Cutler, N.R.2
Allman, R.M.3
-
56
-
-
0032790021
-
Becaplermin gel in the treatment of pressure ulcers: A Phase II randomized, double-blind, placebo-controlled study
-
Rees RS, Robson MC, Smiell JM et al. Becaplermin gel in the treatment of pressure ulcers: a Phase II randomized, double-blind, placebo-controlled study. Wound Rep Regen. 1999; 7:141-7.
-
(1999)
Wound Rep Regen
, vol.7
, pp. 141-147
-
-
Rees, R.S.1
Robson, M.C.2
Smiell, J.M.3
-
57
-
-
0034089949
-
Healing of diabetic foot ulcers and pressure ulcers with human skin equivalent: A new paradigm in wound healing
-
Brem H, Balledux J, Bloom T et al. Healing of diabetic foot ulcers and pressure ulcers with human skin equivalent: a new paradigm in wound healing. Arch Surg. 2000; 135:627-34.
-
(2000)
Arch Surg
, vol.135
, pp. 627-634
-
-
Brem, H.1
Balledux, J.2
Bloom, T.3
-
58
-
-
0033971707
-
Recent advances in wound healing
-
Bello Y, Phillips TJ. Recent advances in wound healing. JAMA. 2000; 283:716-8.
-
(2000)
JAMA
, vol.283
, pp. 716-718
-
-
Bello, Y.1
Phillips, T.J.2
-
59
-
-
8344275529
-
-
East Hanover, NJ: Novartis Pharmaceutical Corporation; Feb.
-
Apligraf product information. East Hanover, NJ: Novartis Pharmaceutical Corporation; 2002 Feb.
-
(2002)
Apligraf Product Information
-
-
-
60
-
-
8344275530
-
-
Dermagraft product information. http:// wound.smith-nephew.com/US/ Product.asp?NodeId=2550 (accessed 2004 Feb 19).
-
Dermagraft Product Information
-
-
-
62
-
-
0026065423
-
Wound infection under occlusive dressings
-
Hutchinson JJ, Lawrence JC. Wound infection under occlusive dressings. J Hosp Infect. 1991; 17:83-94.
-
(1991)
J Hosp Infect
, vol.17
, pp. 83-94
-
-
Hutchinson, J.J.1
Lawrence, J.C.2
-
63
-
-
0019487435
-
Investigation into the microbial flora of healing and non-healing decubitis ulcers
-
Daltrey DC, Rhodes B, Chattwood JG. Investigation into the microbial flora of healing and non-healing decubitis ulcers. J Clin Pathol. 1981; 34:701-5.
-
(1981)
J Clin Pathol
, vol.34
, pp. 701-705
-
-
Daltrey, D.C.1
Rhodes, B.2
Chattwood, J.G.3
-
65
-
-
0026705885
-
Infected pressure sores: Comparison of methods for bacterial identification
-
Rudensky B, Lipschits M, Isaacsohn M et al. Infected pressure sores: comparison of methods for bacterial identification. South Med J. 1992; 85:901-3.
-
(1992)
South Med J
, vol.85
, pp. 901-903
-
-
Rudensky, B.1
Lipschits, M.2
Isaacsohn, M.3
-
69
-
-
0017132678
-
Sepsis associated with decubitus ulcers
-
Galpin JE, Chow AW, Bayer AS et al. Sepsis associated with decubitus ulcers. Am J Med. 1976; 61:346-50.
-
(1976)
Am J Med
, vol.61
, pp. 346-350
-
-
Galpin, J.E.1
Chow, A.W.2
Bayer, A.S.3
-
71
-
-
76549166141
-
Relationship of quantitative wound bacterial counts to healing of decubiti: Effect of topical gentamicin
-
Bendy RH, Nuccio PA, Wolfe E et al. Relationship of quantitative wound bacterial counts to healing of decubiti: effect of topical gentamicin. Antimicrob Agents Chemother. 1964; 4:147-55.
-
(1964)
Antimicrob Agents Chemother
, vol.4
, pp. 147-155
-
-
Bendy, R.H.1
Nuccio, P.A.2
Wolfe, E.3
-
72
-
-
0019465258
-
Comparison of silver sulfadiazine, povidone-iodine and physiologic saline in the treatment of chronic pressure ulcers
-
Kucan JO, Robson MC, Heggers JP et al. Comparison of silver sulfadiazine, povidone-iodine and physiologic saline in the treatment of chronic pressure ulcers. J Am Geriatr Soc. 1981; 29:232-5.
-
(1981)
J Am Geriatr Soc
, vol.29
, pp. 232-235
-
-
Kucan, J.O.1
Robson, M.C.2
Heggers, J.P.3
-
73
-
-
0021081262
-
Topical metronidazole therapy for pressure sores of geriatric patients
-
Gomolin IH, Brandt JL. Topical metronidazole therapy for pressure sores of geriatric patients. J Am Geriatr Soc. 1983; 31:710-2.
-
(1983)
J Am Geriatr Soc
, vol.31
, pp. 710-712
-
-
Gomolin, I.H.1
Brandt, J.L.2
-
74
-
-
0025994340
-
Topical metronidazole gel. the bacteriology of decubitus ulcers
-
Witkowski JA, Parish LC. Topical metronidazole gel. The bacteriology of decubitus ulcers. Int J Dermatol. 1991; 30: 660-1.
-
(1991)
Int J Dermatol
, vol.30
, pp. 660-661
-
-
Witkowski, J.A.1
Parish, L.C.2
|