Fatigue and physical activity levels in patients with liver cirrhosis

Journal of Clinical Nursing

Volumn 21, Issue 1-2, 2012, Pages 129-138

  Wu, Li Jan ^a   Wu, Ming Shun ^a   Lien, Gi Shih ^a   Chen, Feng Chia ^a   Tsai, Jen Chen ^b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Chronic liver disease; Exercise; Fatigue; Liver cirrhosis; Nurses; Nursing; Physical activity; Symptom

Indexed keywords

AGED; ARTICLE; EXERCISE; FATIGUE; HUMAN; LIVER CIRRHOSIS; MIDDLE AGED; PATHOPHYSIOLOGY; TAIWAN;

AGED; EXERCISE; FATIGUE; HUMANS; LIVER CIRRHOSIS; MIDDLE AGED; TAIWAN;

EID: 83355173937     PISSN: 09621067     EISSN: 13652702     Source Type: Journal    
DOI: 10.1111/j.1365-2702.2011.03900.x     Document Type: Article

References (45)

1. Barkhuizen A, Rosen HR, Wolf S, Flora K, Benner K & Bennett RM (1999) Musculoskeletal pain and fatigue are associated with chronic hepatitis C: a report of 239 hepatology clinic patients. American Journal of Gastroenterology 94, 1355-1360.
2. Barofsky I & Legro MW (1991) Definition and measurement of fatigue: approaches to data collection. Reviews of Infectious Diseases 13, S94-S97.
3. Biagini MR, Tozzi A, Milani S, Grippo A, Amantini A, Capanni M, Galli A & Surrenti C (2008) Fatigue in primary biliary cirrhosis: a possible role of comorbidities. European Journal of Gastroenterology and Hepatology 20, 122-126.
4. Björnsson E, Simren M, Olsson R & Chapman RW (2005) Fatigue is not a specific symptom in patients with primary biliary cirrhosis. European Journal of Gastroenterology and Hepatology 17, 351-357.
5. Björnsson E, Kalaitzakis E, Neuhauser M, Enders F, Maetzel H, Chapman RW, Talwalkar J, Lindor K & Jorgensen R (2009) Fatigue measurements in patients with primary biliary cirrhosis and the risk of mortality during follow-up. Liver International 30, 251-258.
6. Blair SN, Haskell WL, Ho P, Paffenbarger RS, Vranizan KM, Farquhar JW & Wood PD (1985) Assessment of habitual physical activity by a Seven-Day Recall in community-survey and controlled experiments. American Journal of Epidemiology 122, 794-804.
7. Cauch-Dudek K, Abbey S, Stewart DE & Heathcote EJ (1998) Fatigue in primary biliary cirrhosis. Gut 43, 705-710.
8. Chen PH, Chen JD & Lin YC (2009) A better parameter in prediction insulin resistance: obesity plus elevated alanine aminotransferase. World Journal of Gastroenterology 15, 5598-5603.
9. Department of Health (2008) Result of Cause of Death. Department of Health (DOH), Taiwan. Available at: (accessed 30 December 2009).
10. Elbers R, Wegen EV, Rochester L, Hetherington V, Nieuwboer A, Willems AM, Jones D & Kwakkel G (2009) Is impact of fatigue an independent factor associated with physical activity in patients with idiopathic Parkinson's disease?. Movement Disorders 24, 1512-1518.
11. Foster GR, Goldin RD & Thomas HC (1998) Chronic hepatitis C virus infection causes a significant reduction in quality of life in the absence of cirrhosis. Hepatology 27, 209-212.
12. Frith J, Day CP, Robinson L, Elliott C, Jones DEJ & Newton JL (2010) Potential strategies to improve uptake of exercise interventions in non-alcoholic fatty liver disease. Journal of Hepatology 52, 112-116.
13. Goldblatt J, Taylor PJ, Lipman T, Prince MI, Baragiotta A & Bassendine MF (2002) The true impact of fatigue in primary cirrhosis: a population study. Gastroenterology 122, 1235-1241.
14. Hann DM, Jacobsen PB, Azzarello LM, Martin SC, Curran SL & Fields KK (1998) Measurement of fatigue in cancer patients: development and validation of the Fatigue Symptom Inventory. Quality of Life Research 7, 301-310.
15. Hann DM, Denniston MM & Baker F (2000) Measurement of fatigue in cancer patients: further validation of the Fatigue Symptom Inventory. Quality of Life Research 9, 847-854.
16. Hauser W, Almouhtassb R, Muthny FA & Grandt D (2003) Validation of a German version of the Fatigue Impact Scale FIS-D. Gastroenterology 41, 973-982.
17. Huet PM, Deslauriers J, Tran A, Faucher C & Charbonneau J (2000) Impact of fatigue on the quality of life of patients with primary biliary cirrhosis. American Journal of Gastroenterology 95, 760-767.
18. Irvine D, Vincent L, Graydon JE, Bubela N & Thompson L (1994) The prevalence and correlates of fatigue in patients receiving treatment with chemotherapy and radiotherapy; a comparison with the fatigue experienced by healthy individuals. Cancer Nursing 17, 367-378.
19. Ishida A, Sumiya N & Ueno F (1996) The effects of physical activity on rehabilitation for acute hepatitis. Tokai Journal of Experimental and Clinical Medicine 21, 1-6.
20. Kim SH, Oh EG & Lee WH (2006) Symptom experience, psychological distress and quality of life in Korean patients with liver cirrhosis: a cross-sectional survey. International Journal of Nursing Studies 43, 1047-1056.
21. Kop WJ, Lyden A, Berlin AA, Ambrose K, Olsen C, Gracely RH, Williams DA & Clanw DJ (2005) Ambulatory monitoring of physical activity and symptoms in fibromyalgia and chronic fatigue syndrome. Arthritis and Rheumatism 52, 296-303.
22. Lai YH, Shun SC, Hsiao YL, Chiou JF, Wei LL, Tsai JT & Kao CY (2007) Fatigue experiences in hepatocellular carcinoma patients during six weeks of stereotactic radiotherapy. The Oncologist 12, 221-230.
23. Lin CL, Chen M, Chung M & Lin MH (2004) The effect of sub-maximal exercise upon students suffering chronic hepatitis B infection. Journal of Internal Medicine of Taiwan 15, 208-213.
24. Mayo MJ (2003) Primary biliary cirrhosis: the future. Clinics in Liver Disease 7, 957-969.
25. Merican I, Sherlock S, McIntyre N & Dusheiko GM (1993) Clinical, biochemical and histological features in 102 patients with chronic hepatitis C virus infection. Quarterly Journal of Medicine 86, 119-125.
26. Miller DJ, Freedson PS & Kline GM (1994) Comparison of activity levels using the Caltrac accelerometer and five questionnaires. Medicine and Science in Sports and Exercise 26, 376-382.
27. Munch TN, Zhang T, Willey J, Palmer JL & Bruera E (2005) The association between anemia and fatigue in patients with advanced cancer receiving palliative care. Journal of Palliative Medicine 8, 1144-1149.
28. Nambu M & Iijima T (1990) Indocuanine green (ICG) test before and after exercise in patients with chronic liver disease. Gastroenterologia Japonica 25, 212-217.
29. Newton JL, Jones DEJ, Henderson E, Kane L, Wilton K, Burt AD & Day CP (2008) Fatigue in non-alcoholic fatty liver disease (NAFLD) is significant and associates with inactivity and excessive daytime sleepiness but not with liver disease severity or insulin resistance. Gut 57, 807-813.
30. Newton JL, Pairman J, Wilton K, Jones DEJ & Day C (2009) Fatigue and autonomic dysfunction in non-alcoholic fatty liver disease. Clinical Autonomic Research 19, 319-326.
31. Nielsen HB, Secher NH, Clemmesen O & Ott P (2005) Maintained cerebral and skeletal muscle oxygenation during maximal exercise in patients with liver cirrhosis. Journal of Hepatology 43, 266-271.
32. Patt CH, Fairbanks KD & Thuluvath PJ (2004) Renal insufficiency may partly explain chronic anemia in patients awaiting liver transplantation. Digestive Diseases and Sciences 49, 629-632.
33. Pereira MA, FitzerGerald SJ, Gregg EW, Joswiak ML, Ryan WJ, Suminski RR, Utter AC & Zmuda JM (1997) A collection of physical activity questionnaires for health-related research. Medicine and Science in Sports and Exercise 29, S1-S205.
34. Piche T, Gelsi E, Schneider SM, Hebuterne X, Giudicelli J, Ferrua B, Laffont C, Benzaken S, Hastier P, Montoya ML, Longo F, Rampal P & Tran A (2003) Fatigue is associated with high circulating leptin levels in chronic hepatitis C. Gut 51, 915.
35. Plow MA, Mathiowetz V & Lowe DA (2009) Comparing individualized rehabilitation to a group wellness intervention for persons with multiple sclerosis. American Journal of Health Promotion 24, 23-26.
36. Prince MI, James OF, Holland NP & Jones DE (2000) Validation of a fatigue impact score in primary biliary cirrhosis: towards a standard for clinical and trial use. Journal of Hepatology 32, 3668-3673.
37. Riley MD & Bhatti MD (2001) Preventive strategies in chronic liver disease: part II cirrhosis. American Academy of Family Physicians 64, 1735-1740.
38. Roussel M, Benard C, Ly-Sunnaram B & Fest T (2010) Refining the white blood cell differential: the first flow cytometry routine application. Cytometry Part A 77A, 552-563.
39. Sarna L & Conde F (2001) Physical activity and fatigue during radiation therapy: a pilot study using actigraph monitors. Oncology Nursing Forum 28, 1043-1046.
40. Sato Y, Sato H, Funasako M & Ohata M (1997) Effects of exercise load on hepatic blood flow in patients with chronic liver diseases. Journal of Medical Ultrasonics 24, 11-12.
41. Snow KK, Bonkovsky HL, Fontana RJ, Kim HY, Sterling RK, Bisceglie AMD, Morgan TR, Dienstag JL, Ghany MG & The Halt-C Trial Group (2010) Changes in quality of life and sexual health are associated with low-dose peginterferon therapy and disease progression in patients with chronic hepatitis C. Alimentary Pharmacology & Therapeutics 31, 719-734.
42. Stanca CM, Bach N, Krause C, Tandon N, Freni MA, Gutierrez JA, Bodian C, Lopez J, Berk PJ, Bodenheimer HC, Branch AD & Odin JA (2005) Evaluation of fatigue in U.S. patients with primary biliary cirrhosis. American Journal of Gastroenterology 100, 1104-1109.
43. Vercoulen JH, Bazelmans E, Swanink CM, Fennis JF, Galama JM, Jongen PJ, Hommes O, VanDerMeer JW & Bleijenberg G (1997) Physical activity in chronic fatigue syndrome: assessment and its role in fatigue. Journal of Psychiatric Research 31, 661-673.
44. Wang XS, Giralt SA, Mendoza TR, Engstrom MC, Johnson BA, Peterson N, Broemeling LD & Cleeland CS (2002) Clinical factors associated with cancer-related fatigue in patients being treated for leukemia and non-Hodgkin's lymphoma. Journal of Clinical Oncology 20, 1319-1328.
45. Welk GJ, Blair SN, Wood K, Jones S & Thompson RW (2000) A comparative evaluation of three accelerometry based activity monitors. Medicine Science in Sports and Exercise 32, S489-S497.