Effect of oligonucleotide mediated immobilization of bone morphogenic proteins on titanium surfaces

Biomaterials

Volumn 33, Issue 5, 2012, Pages 1315-1322

  Schliephake, Henning ^a   Bötel, Christian ^a   Förster, Anne ^b   Schwenzer, Bernd ^b   Reichert, Judith ^b   Scharnweber, Dieter ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Biofunctionalization; Bone morphogenic proteins; Controlled release; Oligonucleotides; Recombinant proteins; Titanium

Indexed keywords

ALKALINE PHOSPHATASE; BINDING CAPACITIES; BINDING STUDIES; BIOFUNCTIONALIZATION; BONE MORPHOGENIC PROTEIN; BONE MORPHOGENIC PROTEINS; COMPLEMENTARY STRAND; CONTROLLED RELEASE; DNA OLIGONUCLEOTIDES; FOCAL ADHESIONS; GROWTH FACTOR; HUMAN BONE MARROW; NON-CODING DNA; OSTEOGENIC; OSTEOGENIC ACTIVITY; OSTEOPONTIN; RECOMBINANT PROTEIN; RELEASE EXPERIMENTS; RHBMP-2; SLOW GROWTH; SLOW RELEASE; STROMA CELLS; TITANIUM IMPLANT SURFACE; TITANIUM SURFACES;

ADHESION; BIOACTIVITY; BIOMATERIALS; BONE; PEPTIDES; PHOSPHATASES; TITANIUM;

OLIGONUCLEOTIDES;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; DNA; OLIGONUCLEOTIDE; OSTEOPONTIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; TITANIUM;

ARTICLE; BONE MARROW CELL; BONE MARROW STROMA CELL; CELL PROLIFERATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PRIORITY JOURNAL; STROMA CELL;

ALKALINE PHOSPHATASE; BONE AND BONES; BONE MARROW CELLS; BONE MORPHOGENETIC PROTEIN 2; CELL PROLIFERATION; CORE BINDING FACTOR ALPHA 1 SUBUNIT; FOCAL ADHESIONS; HUMANS; IMMOBILIZED PROTEINS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; OLIGONUCLEOTIDES; ORGAN SPECIFICITY; RECOMBINANT PROTEINS; STROMAL CELLS; SURFACE PROPERTIES; TITANIUM; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 83355173911     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.10.027     Document Type: Article

References (32)

1. Junker R., Dimakis A., Thoneick M., Jansen J.A. Effects of implant surface coatings and composition on bone integration. Clin Oral Implants Res 2009, 20:185-206.
2. Schliephake H., Scharnweber D. Chemical and biological functionalization of titanium for dental implants. J Mater Chem 2008, 10.1039/b715355b.
3. Lutz R., Srour S., Nonhoff J., Weisel T., Damien C.J., Schlegel K.A. Biofunctionalization of titanium implants with a biomimetic active peptide (P-15) promotes early osseointegration. Clin Oral Implants Res 2010, 21:726-734.
4. Khatayevich D., Gungormus M., Yaziuci H., So C., Cetinel S., Ma H., et al. Biofunctionalization of materials for implants using engineered peptides. Acta Biomater 2010, 6:4634-4641.
5. Petzrie T.A., Reyes C.D., Burns K.L., Garcia A.J. Simple application of fibronectin-mimetic coating enhances osseointegration of titanium implants. J Cell Mol Med 2009, 13:2602-2612.
6. 2/perlite composite and its surface modification with fibronectin. Biomaterials 2005, 26:2812-2826.
7. Graf H.L., Stoeva S., Armbruster F.P., Neuhaus J., Hilbig H. Effect of bone sialoprotein and collagen coating on cell attachment to TICER and pure titanium surfaces. Int J Oral Maxillofac Surg 2008, 37:634-640.
8. Stadlinger B., Pilling E., Hulhe M., Mai R., Bierbaum S., Bernhard R., et al. Influence of extracellular matrix coatings on implant stability and osseointegration: an animal study. J Biomed Mater Res 2007, 83:222-231.
9. Park J.M., Koak J.Y., Jang J.H., Han C.H., Kim S.K., Heo S.J. Osseointegration of anodized titanium implants coated with fibroblast growth factor -fibronectin (FGF-FN) fusion protein. Int J Oral Maxillofac Implants 2006, 21:859-866.
10. Schliephake H., Scharnweber D., Dard M., Sewing A., Roessler S., Meyer J., et al. Effect of RGD peptide coating of titanium implants on periimplant bone formation in the alveolar crest. Clin Oral Impl Res 2002, 13:312-319.
11. Schliephake H., Scharnweber D., Dard M., Sewing A., Aref A., Roessler S. Functionalization of dental implant surfaces using adhesion molecules. J Biomed Mater Res B Appl Biomater 2005, 73B:88-96.
12. Schliephake H., Aref A., Scharnweber D., Bierbaum S., Roessler S., Sewing A. Effect of immobilized bone morphogenic protein 2 coating of titanium implants on periimplant bone formation. Clin Oral Impl Res 2005, 16:563-569.
13. Abarrategi A., Garcia- Cantalejo J., Moreno-Vicente C., Civantos A., Ramos V., Casado J.V., et al. Gene expression profile on chitosan/rhBMP-2 films: a novel osteoinductive coating for implantable materials. Acta Biomater 2009, 5:2633-2646.
14. Lamberg A., Berchtold J.E., Baas J., Soballe K., Elmengaard B. Effect of local TGF-beta1 and IGF-1 release on implant fixation: comparison with hydroxyapatite coating: a paired study in dogs. Acta Orthop 2009, 80:499-504.
15. Lee S.Y., Koak S.Y., Heo S.J., Kim S.K., Lee S.J., Nam S.Y. Osseointegration of anodized titanium implants coated with poly(lactide-co-glycolide) basic fibroblast growth factor by electrospray. Int J Oral Maxillofac Implants 2010, 25:315-320.
16. Hall J., Sorensen R.G., Wozney J.M., Wikesjö U.M. Bone formation at rhBMP-2-coated titanium implants in the rat ectopic model. J Clin Periodontol 2007, 34:444-451.
17. Wikesjö U.M., Qahash M., Polimeni G., Susin C., Shanaman R.H., Rohrer M.D., et al. Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: histologic observations. J Clin Periodontol 2008, 35:1001-1010.
18. Leknes K.N., Yang J., Qahash M., Polimeni G., Susin C., Wikesjö U.M. Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: radiographic observations. Clin Oral Implants Res 2008, 19:1027-1033.
19. Adden N., Gamble L.J., Castner D.G., Hoffmann A., Gross G., Menzel H. Phosphonic acid monolayers for binding of bioactive molecules to titanium surfaces. Langmuir 2006, 22:8197-8204.
20. Adden N., Gamble L.J., Castner D.G., Hoffmann A., Gross G., Menzel H. Synthesis and characterization of biocompatible polymer interlayers on titanium implant materials. Biomacromolecules 2006, 7:2552-2559.
21. Seol Y.J., Park Y.J., Lee S.C., Kim K.H., Lee J.Y., Kim T.I., et al. Enhanced osteogenic promotion around dental implants with synthetic binding motif mimicking bone morphogenetic protein (BMP)-2. J Biomed Mater Res A 2006, 77:599-607.
22. Bernhardt R., van den Dolder J., Bierbaum S., Beutner R., Scharnweber D., Jansen J., et al. Osteoconductive modifications of Ti-implants in a goat defect model: characterization of bone growth with SR muCT and histology. Biomaterials 2005, 26:3009-3019.
23. Michael J., Beutner R., Hempel U., Scharnweber D., Worch H., Schwenzer B. Surface modification of titanium-based alloys with bioactive molecules using electrochemically fixed nucleic acids. J Biomed Mater Res B Appl Biomater 2007, 80:146-155.
24. Beutner R., Michael J., Förster A., Schwenzer B., Scharnweber D. Immobilization of oligonucleotides on titanium based materials by partial incorporation in anodic oxide layers. Biomaterials 2009, 30:2774-2781.
25. Scharnweber D., Schlottig F., Oswald S., Becker K., Worch H. How is wettability of titanium surfaces influenced by their preparation and storage conditions?. J Mater Sci: Mater Med 2010, 21:525-532.
26. Michael J., Schonzart L., Israel I., Beutner R., Scharnweber D., Worch H., et al. Oligonucleotide-RGD peptide conjugates for surface modification of titanium implants and improvement of osteoblast adhesion. Bioconjug Chem 2009, 20:710-718.
27. Fromigué O., Marie P.J., Lomri A. Bone morphogenetic protein-2 and transforming growth factor-beta2 interact to modulate human bone marrow stromal cell proliferation and differentiation. J Cell Biochem 1998, 68:411-426.
28. Su J.L., Chiou J., Tang C.H., Zhao M., Tsai C.H., Chem P.S., et al. CYR61 regulates BMP-2-dependent osteoblast differentiation through the αvβ3 Integrin/Integrin-linked Kinase/ERK Pathway. J Biolog Chem 2010, 285:31325-31336.
29. Kloss F.R., Gassner R., Preiner J., Ebner A., Larsson K., Hächl O., et al. The role of oxygen termination ofnanocrystalline diamond on immobilisation of BMP-2 and subsequent bone formation. Biomaterials 2008, 29:2433-2442.
30. Kashiwagi K., Tsuji T., Shiba K. Directional BMP-2 for functionalization of titanium surfaces. Biomaterials 2009, 301166-301175.
31. Von Walter M., Herren C., Gensior T.J., Steffens G.C., Hermanns-Sachweh B., Jahnen-Dechent W., et al. Biomimetic modification of the TiO(2)/glass composite Ecopore with heparinized collagen and the osteoinductive factor BMP-2. Acta Biomater 2008, 4:997-1004.
32. Mitchel E.A., Chaffey B.T., McCaskie A.W., Lakey J.H., Birch M.A. Controlled spatial and conformational display of immobilized bone morphogenic protein-2 and osteopontin signaling motifs regulate osteoblast adhesion and differentiation in vitro. BMC Biol 2010, 8:57-58.