메뉴 건너뛰기




Volumn 29, Issue 34, 2011, Pages 4589-4590

CYP2D6 and tamoxifen: Awaiting the denouement

Author keywords

[No Author keywords available]

Indexed keywords

ANASTROZOLE; BIOLOGICAL MARKER; CYTOCHROME P450 2D6; ENDOXIFEN; TAMOXIFEN;

EID: 83355169746     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2011.38.8611     Document Type: Letter
Times cited : (13)

References (10)
  • 1
    • 80052020634 scopus 로고    scopus 로고
    • Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: A multicenter study
    • Irvin WJ Jr, Walko CM, Weck KE, et al: Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: A multicenter study. J Clin Oncol 29:3232-3239, 2011
    • (2011) J Clin Oncol , vol.29 , pp. 3232-3239
    • Irvin Jr., W.J.1    Walko, C.M.2    Weck, K.E.3
  • 2
    • 80051995856 scopus 로고    scopus 로고
    • Personalized tamoxifen: What is the best way forward?
    • Rae JM: Personalized tamoxifen: What is the best way forward? J Clin Oncol 29:3206-3208, 2011
    • (2011) J Clin Oncol , vol.29 , pp. 3206-3208
    • Rae, J.M.1
  • 3
    • 79959353859 scopus 로고    scopus 로고
    • Lack of correlation between gene variants in tamoxifen metabolizing enzymes with primary endpoints in the ATAC trial
    • suppl; abstr S1-7
    • Rae JM, Drury S, Hayes DF, et al: Lack of correlation between gene variants in tamoxifen metabolizing enzymes with primary endpoints in the ATAC trial. Cancer Res 70, 2010 (suppl; abstr S1-7)
    • (2010) Cancer Res , vol.70
    • Rae, J.M.1    Drury, S.2    Hayes, D.F.3
  • 4
    • 79959367176 scopus 로고    scopus 로고
    • Outcome according to CYP2D6 genotype among postmenopausal women with endocrine-responsive early invasive breast cancer randomized in the BIG 1-98 trial
    • suppl; abstr S1-8
    • Leyland-Jones B, Regan MM, Bouzyk M, et al: Outcome according to CYP2D6 genotype among postmenopausal women with endocrine-responsive early invasive breast cancer randomized in the BIG 1-98 trial. Cancer Res 70, 2010 (suppl; abstr S1-8)
    • (2010) Cancer Res , vol.70
    • Leyland-Jones, B.1    Regan, M.M.2    Bouzyk, M.3
  • 5
    • 33644639136 scopus 로고    scopus 로고
    • Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes
    • Goetz MP, Rae JM, Suman VJ, et al: Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes. J Clin Oncol 23:9312-9318, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 9312-9318
    • Goetz, M.P.1    Rae, J.M.2    Suman, V.J.3
  • 6
    • 70349929431 scopus 로고    scopus 로고
    • Association between CYP2D6 polymorphisms and outcomes among women with early breast cancer treated with tamoxifen
    • Schroth W, Goetz MP, Hamann U, et al: Association between CYP2D6 polymorphisms and outcomes among women with early breast cancer treated with tamoxifen. JAMA 302:1429-1436, 2009
    • (2009) JAMA , vol.302 , pp. 1429-1436
    • Schroth, W.1    Goetz, M.P.2    Hamann, U.3
  • 7
    • 79955480679 scopus 로고    scopus 로고
    • Activity levels of tamoxifen metabolites at the estrogen receptor and the impact of genetic polymorphisms of phase I and II enzymes on their concentration levels in plasma
    • Mürdter TE, Schroth W, Bacchus-Gerybadze L, et al: Activity levels of tamoxifen metabolites at the estrogen receptor and the impact of genetic polymorphisms of phase I and II enzymes on their concentration levels in plasma. Clin Pharmacol Ther 89:708-717, 2011
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 708-717
    • Mürdter, T.E.1    Schroth, W.2    Bacchus-Gerybadze, L.3
  • 8
    • 79955485361 scopus 로고    scopus 로고
    • Tamoxifen metabolite concentrations, CYP2D6 genotype, and breast cancer outcomes
    • Madlensky L, Natarajan L, Tchu S, et al: Tamoxifen metabolite concentrations, CYP2D6 genotype, and breast cancer outcomes. Clin Pharmacol Ther 89:718-725, 2011
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 718-725
    • Madlensky, L.1    Natarajan, L.2    Tchu, S.3
  • 9
    • 41949104971 scopus 로고    scopus 로고
    • Relationship between quantitative estrogen and progesterone receptor expression and human epidermal growth factor receptor 2 (HER-2) status with recurrence in the Arimidex, Tamoxifen, Alone or in Combination trial
    • Dowsett M, Allred C, Knox J, et al: Relationship between quantitative estrogen and progesterone receptor expression and human epidermal growth factor receptor 2 (HER-2) status with recurrence in the Arimidex, Tamoxifen, Alone or in Combination trial. J Clin Oncol 26:1059-1065, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 1059-1065
    • Dowsett, M.1    Allred, C.2    Knox, J.3
  • 10
    • 73549113692 scopus 로고    scopus 로고
    • Pharmacogenetic (CYP2D6) and gene expression profiles (HOXB13/IL17BR and molecular grade index) for prediction of adjuvant endocrine therapy benefit in the ABCSG 8 trial
    • suppl; abstr 57
    • Goetz MP, Ames MM, Gnant M, et al: Pharmacogenetic (CYP2D6) and gene expression profiles (HOXB13/IL17BR and molecular grade index) for prediction of adjuvant endocrine therapy benefit in the ABCSG 8 trial. Cancer Res 69, 2008 (suppl; abstr 57)
    • (2008) Cancer Res , vol.69
    • Goetz, M.P.1    Ames, M.M.2    Gnant, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.