Enhancing ventilation in homes of children with asthma: Pragmatic randomised controlled trial

British Journal of General Practice

Volumn 61, Issue 592, 2011, Pages

  Woodfine, Louise ^a   Neal, Richard D ^b   Bruce, Nigel ^c   Edwards, Rhiannon T ^d   Linck, Pat ^d   Mullock, Linda ^a   Nelhans, Nick ^f   Pasterfield, Diana ^b   Russell, Daphne ^e   Russell, Ian ^g  

^a PUBLIC HEALTH WALES   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d BANGOR UNIVERSITY   (United Kingdom)

^e BANGOR UNIVERSITY   (United Kingdom)

^f WREXHAM MAELOR HOSPITAL   (United Kingdom)

^g SWANSEA UNIVERSITY   (United Kingdom)

Author keywords

Asthma; Children; Clinical trials, randomised; General practice health; Housing; Quality of life

Indexed keywords

ABSENTEEISM; ADOLESCENT; AIR CONDITIONING; ARTICLE; ASTHMA; CHILD; DISEASE SEVERITY; HOME CARE; HUMAN; MAJOR CLINICAL STUDY; PRESCHOOL CHILD; QUALITY OF LIFE; SCHOOL CHILD; TEMPERATURE;

ABSENTEEISM; ADOLESCENT; ASTHMA; CHILD; CHILD, PRESCHOOL; FEMALE; HEALTH STATUS; HEATING; HOUSING; HUMANS; MALE; PROGNOSIS; QUALITY OF LIFE; QUESTIONNAIRES; VENTILATION; WALES;

EID: 83355167008     PISSN: 09601643     EISSN: None     Source Type: Journal    
DOI: 10.3399/bjgp11X606636     Document Type: Article

References (26)

1. Thomson H, Petticrew M, Morrison D. Health effects of housing improvements: systematic review of intervention studies. BMJ 2001; 323(7306): 187-190. (Pubitemid 32682087)
2. Thomson H, Thomas S, Sellstrom E, et al. The health impacts of housing improvement: a systematic review of intervention studies from1887 to 2007. Am J Public Health 2009; 99(Suppl 3): S681-S692.
3. Thomson H, Petticrew M. Housing and health. BMJ 2007; 334(7591): 434-435. (Pubitemid 46586588)
4. Asthma UK. What is asthma? London: Asthma UK, 2007. www.asthma.org.uk/ news-media/media-resources/for-journalists.html#what-is-asthma (accessed 22 Jul 2011).
5. Bush RK, Portnoy JM, Saxon A, et al. The medical effects of mould exposure. J Allergy Clin Immunol 2006; 117(2): 326-333.
6. Zock JP, Jarvis D, Luczynska C, et al. Housing characteristics, reported mold exposure, and asthma in the European Community Respiratory Health Survey. J Allergy Clin Immunol 2002; 110(2): 285-292.
7. Sharma HP, Hansel NN, Matsui E, et al. Indoor environmental influences on children's asthma. Pediatr Clin N Am 2007; 54(1): 103-120. (Pubitemid 46240080)
8. Gotzsche PC, Johansen HK. House dust mite control measures for asthma. Cochrane Database Syst Rev 2008; (2):CD001187.
9. Custovic A, Simpson BM, Simpson A, et al. Manchester asthma and allergy study: low-allergen environment can be achieved and maintained during pregnancy and in early life. J Allergy Clin Immunol 2000; 105(2Pt 1): 252-258. (Pubitemid 30109037)
10. Warner JA, Frederick JM, Bryant TN, et al. Mechanical ventilation and high-efficiency vacuum cleaning: a combined strategy of mite and mite allergen reduction in the control of mite-sensitive asthma. J Allergy Clin Immunol 2000; 105(1Pt 1): 75-82. (Pubitemid 30059106)
11. Wright GR, Howieson S, McSharry C, et al. Effect of improved home ventilation on asthma control and house dust mite allergen levels. Allergy 2009; 64(11): 1671-1680.
12. Krieger JW, Takaro TK, Song L, et al. The Seattle-King County Healthy Homes Project: a randomized, controlled trial of a community health worker intervention to decrease exposure to indoor asthma triggers. Am J Public Health 2005; 95(4): 652-659. (Pubitemid 40416789)
13. Somerville M, Basham M, Foy C, et al. From local concern to randomized trial: the Watcombe Housing Project. Health Expect 2002; 5(2): 127-135. (Pubitemid 34591873)
14. Barton A, Basham M, Foy C, et al. The Watcombe Housing Study: the short term effect of improving housing conditions on the health of residents. J Epidemiol Community Health 2007; 61(9): 771-777. (Pubitemid 47311715)
15. Burr ML, Matthews IP, Arthur RA, et al. Effects on patients with asthma of eradicating visible indoor mould - randomised controlled trial. Thorax 2007; 62(9): 767-772.
16. Howden-Chapman P, Matheson A, Crane J, et al. Effect of insulating existing homes on health inequality: cluster randomised study in the community. BMJ 2007; 334(7591): 460-464. (Pubitemid 46586603)
17. Howden-Chapman P, Pierse N, Nicholls S, et al. Effects of improved home heating on asthma in community dwelling children: randomised controlled trial. BMJ 2008; 337: a1411.
18. Edwards RT, Neal RD, Linck P, et al., on behalf of the CHARISMA study group. Enhancing ventilation in homes of children with asthma: cost-effectiveness study alongside randomised controlled trial. Br J Gen Pract 2011; 61: 10.3399/bjgp11X606645.
19. Schwartz D, Lellouch J. Explanatory and pragmatic attitudes in therapeutic trials. J Chronic Dis 1967; 20(8): 637-648.
20. Zwarenstein M, Treweek S, Gagnier JJ, et al. Improving the reporting of pragmatic trials: an extension of the ConSORT statement. BMJ 2009; 337: a2390.
21. ISRCTN Register. Children's health in asthma: research to improve status through modifying accommodation. London: Current Controlled Trials Ltd, 2007. http://controlled-trials.com/ISRCTN13912429/13912429 (accessed 22 Jul 2011).
22. Cook TD, Campbell DT. Quasi-experimentation: design and analysis for field settings. Chicago, Illinois: Rand McNally, 1979.
23. Varni JW, Seid M, Kurtin PS. PedsQL 4.0: reliability and validity of the pediatric quality of life inventory version 4.0 generic core scales in healthy and patient populations. Med Care 2001; 39(8): 800-812. (Pubitemid 33686263)
24. Varni JW, Burwinkle TM, Rapoff MA, et al. The PedsQL in pediatric asthma: reliability and validity of the Pediatric Quality of Life Inventory generic core scales and asthma module. J Behav Med 2004; 27(3): 297-318. (Pubitemid 39024007)
25. Upton P, Eiser C, Cheung WY, et al. Measurement properties of the UK-English version of the Pediatric Quality of Life Inventory 4.0 (PedsQL) generic core scales. Health Qual Life Outcomes 2005; 3: 22.
26. Russell D, Hoare ZSJ, Whitaker RH, et al. Generalised method for adaptive randomisation in clinical trials. Stat Med 2011; 30(9): 922-934.