Identification of P-Rex1 as a novel Rac1-guanine nucleotide exchange factor (GEF) that promotes actin remodeling and GLUT4 protein trafficking in adipocytes

Journal of Biological Chemistry

Volumn 286, Issue 50, 2011, Pages 43229-43240

  Balamatsias, Demis ^a   Kong, Anne M ^a   Waters, Joanne E ^a   Sriratana, Absorn ^a   Gurung, Rajendra ^a   Bailey, Charles G ^b   Rasko, John E J ^b,c   Tiganis, Tony ^a   Macaulay, S Lance ^d   Mitchell, Christina A ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^d CSIRO   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

3T3-L1 ADIPOCYTES; ACTIN CYTOSKELETON; ADIPOCYTES; DOMINANT-NEGATIVE MUTANTS; EXCHANGE FACTORS; GLUCOSE TRANSPORTERS; GLUCOSE UPTAKE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INSULIN CONCENTRATIONS; MEMBRANE RUFFLES; MEMBRANE RUFFLING; PHOSPHOINOSITIDE 3-KINASE; PROTEIN TRAFFICKING; RHO GTPASES;

CELL MEMBRANES; GLUCOSE; INSULIN; MEMBRANES; PLASMAS; TISSUE;

PROTEINS;

ACTIN; GLUCOSE; GLUCOSE TRANSPORTER 4; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN CDC42; PROTEIN P REX1; RAC1 PROTEIN; RHO FACTOR; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADIPOCYTE; AMINO TERMINAL SEQUENCE; ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE; CELL STRAIN 3T3; CONTROLLED STUDY; GENETIC TRANSFECTION; GLUCOSE TRANSPORT; MUTANT; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRAFFICKING;

3T3-L1 CELLS; ACTINS; ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; CELL MEMBRANE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GLUCOSE TRANSPORTER TYPE 4; GUANINE NUCLEOTIDE EXCHANGE FACTORS; IMMUNOBLOTTING; INSULIN; MICE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RAC1 GTP-BINDING PROTEIN; RNA, SMALL INTERFERING;

EID: 83355166914     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.306621     Document Type: Article

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