Nitrous oxide/oxygen compared with fentanyl in reducing pain among adults with isolated extremity trauma: A randomized trial

EMA - Emergency Medicine Australasia

Volumn 23, Issue 6, 2011, Pages 761-768

  Kariman, Hamid ^a   Majidi, Alireza ^a   Amini, Afshin ^a   Arhami Dolatabadi, Ali ^a   Derakhshanfar, Hojjat ^a   Hatamabadi, Hamidreza ^a   Shahrami, Ali ^a   Yaseri, Mahdi ^b   Sheibani, Kourosh ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Emergency medical services; Fentanyl; Nitrous oxide oxygen; Pain

Indexed keywords

FENTANYL; NITROUS OXIDE; OXYGEN;

ADOLESCENT; ADULT; AGED; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; FEMALE; HUMAN; INJURY; JOINT DISLOCATION; LIMB FRACTURE; LIMB PAIN; LONG BONE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE DRUG DOSE; VISUAL ANALOG SCALE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; ANESTHETICS, INHALATION; DISLOCATIONS; EXTREMITIES; FEMALE; FENTANYL; FRACTURES, BONE; HUMANS; MALE; MIDDLE AGED; NITROUS OXIDE; OXYGEN; PAIN; PAIN MEASUREMENT; YOUNG ADULT;

EID: 83355166845     PISSN: 17426731     EISSN: 17426723     Source Type: Journal    
DOI: 10.1111/j.1742-6723.2011.01447.x     Document Type: Article

References (19)

1. Perkins FM, Kehlet H. Chronic pain as an outcome of surgery: a review of predictive factors. Anesthesiology 2000; 93 (4): 1123-33.
2. Sweetman SC. Martindale, the Complete Drug Reference, 34th edn. London: Pharmaceutical, 2005; 71-5.
3. Baskett PJF, Bennett JA. Pain relief in hospital: the more widespread use of nitrous oxide. BMJ 1971; 2: 509-11.
4. Latto IP, Molloy MJ, Rosen M. Arterial concentrations of nitrous oxide during intermittent patient-controlled inhalation of 50% nitrous oxide in oxygen (Entonox) during the first stages of labour. Br. J. Anaesth. 1973; 45: 1029-34.
5. Maslekar S, Balaji P, Gardiner A, Culbert B, Monson JR, Duthie GS. Randomised controlled trial of patient controlled sedation for colonoscopy: entonox versus modified patient maintained target controlled Propofol. Colorectal Dis. 2011; 13( 1): 48-57.
6. Maslekar S, Gardiner A, Hughes M, Culbert B, Duthie GS. Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy. Br. J. Surg. 2009; 96: 361-8.
7. Dell PF, O'Neil JA. Preface. In: Dell PF, O'Neil JA, eds. Dissociation and the Dissociative Disorders: DSM-V and Beyond. New York: Routledge, 2009; xix-xxi.
8. Peate I, Lancaster J. Safe use of medical gases in the clinical setting: practical tips. Br. J. Nurs. 2000; 9: 231-6.
9. Evans A. Use of Entonox in the community for control of procedural pain. Br. J. Community Nurs. 2003; 8: 488-94.
10. Report to the Medical Research Council of the committee on nitrous oxide and oxygen analgesia in midwifery Clinical trials of diVerent concentrations of oxygen and nitrous oxide for obstetric analgesia. BMJ 1970; 1: 709-13.
11. Baskett PJF, Withnell A. Use of Entonox in the ambulance service. BMJ 1970; 2: 41-3.
12. Marsden AK. Entonox in the emergency department. Injury 1979; 10: 311-12.
13. O'Sullivan I, Benger J. Nitrous oxide in emergency medicine. Emerg. Med. J. 2003; 20: 214-17.
14. Amess JA, Burman JF, Rees GM, Nancekievill DG, Mollin DL. Megaloblastic haemopoiesis in patients receiving nitrous oxide. Lancet 1978; 2 (8085): 339-42.
15. Gillman MA. Analgesic (sub anaesthetic) nitrous oxide interacts with the endogenous opioid system. Life Sci. 1986; 39: 1209-11.
16. Haugen FP, Melzack R. The effects of nitrous oxide on responses evoked in the brain stem by tooth stimulation. Anaesthesiology 1957; 18: 183-95.
17. Payne CG, Edbrooke DL, Davies GK. Minor procedures in the accident and emergency department: can Entonox help? Arch. Emerg. Med. 1991; 8: 24-32.
18. Descamps MJ, Gwilym S, Weldon D, Holloway V. Prospective audit of emergency department transit times associated with entonox analgesia for reduction of the acute, traumatic dislocated shoulder. Accid. Emerg. Nurs. 2007; 15: 223-27.
19. Wattenmaker I, Kasser JR, McGravey A. Self-administered nitrous oxide for fracture reduction in children in an emergency room setting. J. Orthop. Trauma 1990; 4: 35-8.