Ring chromosome 22 and neurofibromatosis type II: Proof of two-hit model for the loss of the NF2 gene in the development of meningioma

Clinical Genetics

Volumn 81, Issue 1, 2012, Pages 82-87

  Zirn, B ^a   Arning, L ^b   Bartels, I ^a   Shoukier, M ^a   Hoffjan, S ^b   Neubauer, B ^c   Hahn, A ^c  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Meningioma; Neurofibromatosis type II; NF2 gene; Ring chromosome 22; Tumourigenesis; Two hit model

Indexed keywords

PROTEIN; PROTEIN NF2; UNCLASSIFIED DRUG;

ADOLESCENT; ARTICLE; CASE REPORT; CHROMOSOME 22Q; CHROMOSOME DELETION; COMPARATIVE GENOMIC HYBRIDIZATION; HUMAN; MALE; MENINGIOMA; MENTAL DEFICIENCY; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; NEUROFIBROMATOSIS; PARAPLEGIA; POINT MUTATION; PRIORITY JOURNAL; RING CHROMOSOME; RING CHROMOSOME 22; SPINE TUMOR;

ADOLESCENT; ALLELES; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 22; COMPARATIVE GENOMIC HYBRIDIZATION; GENES, NEUROFIBROMATOSIS 2; GENETIC TESTING; GENOMIC INSTABILITY; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MENINGIOMA; MODELS, GENETIC; NEUROFIBROMATOSIS 2; POINT MUTATION; RING CHROMOSOMES;

EID: 83355163610     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2010.01598.x     Document Type: Article

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