Behavioral effects of sub-acute inhalation of toluene in adult rats

Neurotoxicology and Teratology

Volumn 34, Issue 1, 2012, Pages 83-89

  Beasley, Tracey E ^a   Evansky, Paul A ^a   Bushnell, Philip J ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Behavior; Sub acute toluene; Sustained attention

Indexed keywords

TOLUENE;

ACCURACY; ACUTE TOXICITY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; ATTENTION DISTURBANCE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; MALE; MAZE TEST; MOTOR ACTIVITY; MOTOR DYSFUNCTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL DETECTION; TASK PERFORMANCE; TOXIC INHALATION; VISUAL DISCRIMINATION; VISUAL DISORDER;

ADMINISTRATION, INHALATION; AGING; ANIMALS; BEHAVIOR, ANIMAL; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; INHALATION EXPOSURE; MALE; MENTAL DISORDERS; RATS; RATS, LONG-EVANS; SOLVENTS; TOLUENE;

RATTUS;

EID: 83255189446     PISSN: 08920362     EISSN: 18729738     Source Type: Journal    
DOI: 10.1016/j.ntt.2011.11.001     Document Type: Article

References (38)

1. Ali J.S., Olszyk V.B., Dunn D.D., Lee K.A., Kendall S.M., Rhoderick R.R., et al. A Lotus 1-2-3-based system for recording and maintaing body weight of laboratory animals. Behav Res Methods Instrum Comput 1992, 24:82-87.
2. Beasley T.E., Evansky P.A., Gilbert M.E., Bushnell P.J. Behavioral effects of subchronic inhalation of toluene in adult rats. Neurotoxicol Teratol 2010, 32:611-619.
3. Benevenga N.J., Kaiser M., Clagett-Dame M. Development of the rat loft. Tech Talk 2005, 10:3.
4. Berenguer P., Soulage C., Fautrel A., Pequignot J.M., Abraini J.H. Behavioral and neurochemical effects induced by subchronic combined exposure to toluene at 40ppm and noise at 80dB-A in rats. Physiol Behav 2004, 81:527-534.
5. Berenguer P., Soulage C., Perrin D., Pequignot J.M., Abraini J.H. Behavioral and neurochemical effects induced by subchronic exposure to 40ppm toluene in rats. Pharmacol Biochem Behav 2003, 74:997-1003.
6. Bowen S.E., Batis J.C., Paez-Martinez N., Cruz S.L. The last decade of solvent research in animal models of abuse: mechanistic and behavioral studies. Neurotoxicol Teratol 2006, 28:636-647.
7. Bushnell P.J. Detection of visual signals by rats: effects of signal intensity, event rate and task type. Behav Processes 1999, 46:141-150.
8. Bushnell P.J., Oshiro W.M., Padnos B.K. Detection of visual signals by rats: effects of chlordiazepoxide and cholinergic and adrenergic drugs on sustained attention. Psychopharmacology (Berl) 1997, 134:230-241.
9. Bushnell P.J., Oshiro W.M., Samsam T.E., Benignus V.A., Krantz Q.T., Kenyon E.M. A dosimetric analysis of the acute behavioral effects of inhaled toluene in rats. Toxicol Sci 2007, 99:181-189.
10. Bushnell P.J., Rice D.C. Behavioral assessments of learning and attention in rats exposed perinatally to 3,3',4,4',5-pentachlorobiphenyl (PCB 126). Neurotoxicol Teratol 1999, 21:381-392.
11. Carli M., Robbins T.W., Evenden J.L., Everitt B.J. Effects of lesions to ascending noradrenergic neurones on performance of a 5-choice serial reaction task in rats; implications for theories of dorsal noradrenergic bundle function based on selective attention and arousal. Behav Brain Res 1983, 9:361-380.
12. Conover W.J. The Kruskal-Wallis test. Practical nonparametric statistics 1971, 256-264. John Wiley and Sons Inc., New York.
13. Davenport J. Combined autoshaping-operant (AO) training: CS-UCS interval effects in rats. Bull Psychon Soc 1974, 3:383-385.
14. Eller N., Netterstrom B., Laursen P. Risk of chronic effects on the central nervous system at low toluene exposure. Occup Med (Lond) 1999, 49:389-395.
15. Fuente A., McPherson B. Organic solvents and hearing loss: the challenge for audiology. Int J Audiol 2006, 45:367-381.
16. Gericke C., Hanke B., Beckmann G., Baltes M.M., Kuhl K.P., Neubert D. Multicenter field trial on possible health effects of toluene. III. Evaluation of effects after long-term exposure. Toxicology 2001, 168:185-209.
17. Gobba F., Cavalleri A. Color vision impairment in workers exposed to neurotoxic chemicals. Neurotoxicology 2003, 24:693-702.
18. Hannigan J.H., Bowen S.E. Reproductive toxicology and teratology of abused toluene. Syst Biol Reprod Med 2010, 56:184-200.
19. Hanninen H., Antti-Poika M., Savolainen P. Psychological performance, toluene exposure and alcohol consumption in rotogravure printers. Int Arch Occup Environ Health 1987, 59:475-483.
20. Hillefors-Berglund M., Liu Y., von Euler G. Persistent, specific and dose-dependent effects of toluene exposure on dopamine D2 agonist binding in the rat caudate-putamen. Toxicology 1995, 100:185-194.
21. Iregren A., Andersson M., Nylén P. Color vision and occupational chemical exposures: I. An overview of tests and effects. Neurotoxicology 2002, 23:719-733.
22. Larsen F., Leira H.L. Organic brain syndrome and long-term exposure to toluene: a clinical, psychiatric study of vocationally active printing workers. J Occup Med 1988, 30:875-878.
23. Lomax R.B., Ridgway P., Meldrum M. Does occupational exposure to organic solvents affect colour discrimination?. Toxicol Rev 2004, 23:91-121.
24. Meyer-Baron M. A met-analytical approach to neurobehavioural effects of occupational toluene exposure. Environ Toxicol Pharmacol 2005, 19:651-657.
25. Miyagawa M., Honma T., Sato M. Effects of subchronic exposure to toluene on working and reference memory in rats. Neurotoxicol Teratol 1995, 17:657-664.
26. Norton S., Culver B., Mullenix P. Measurement of the effects of drugs on activity of permanent groups of rats. Psychopharmacol Commun 1975, 1:131-138.
27. Paramei G.V., Meyer-Baron M., Seeber A. Impairments of colour vision Induced by organic solvents: a meta-analysis study. Neurotoxicology 2004, 25:803-816.
28. Reiter L.W., Anderson G.E., Laskey J.W., Cahill D.F. Developmental and behavioral changes in the rat during chronic exposure to lead. Environ Health Perspect 1975, 12:119-123.
29. Samsam T.E., Hunter D.L., Bushnell P.J. Effects of chronic dietary and repeated acute exposure to chlorpyrifos on learning and sustained attention in rats. Toxicol Sci 2005, 87:460-468.
30. Schmajuk N.A., Bushnell P.J. A computational model reveals classical conditioning mechanisms underlying visual signal detection in rats. Behav Process 2009, 82:340-351.
31. Seeber A., Schaper M., Zupanic M., Blaszkewicz M., Demes P., Kiesswetter E., et al. Toluene exposure below 50 ppm and cognitive function: a follow-up study with four repeated measurements in rotogravure printing plants. Int Arch Occup Environ Health 2004, 77:1-9.
32. von Euler G. Toluene and dopaminergic transmission. Toxins in air and water 1994, Vol. 3:301-321. Plenum Press, New York. R.L. Isaccson, K.F. Jensen (Eds.).
33. von Euler G., Fuxe K., Benfenati F., Hansson T., Agnati L.F., Gustafsson J.A. Neurotensin modulates the binding characteristics of dopamine D2 receptors in rat striatal membranes also following treatment with toluene. Acta Physiol Scand 1989, 135:443-448.
34. von Euler G., Fuxe K., Hansson T., Eneroth P., Agnati L.F., Harfstrand A., et al. Effects of acute haloperidol treatment on regional catecholamine levels and utilization in rats exposed to toluene. Acta Physiol Scand 1988, 132:199-208.
35. von Euler G., Ogren S.O., Bondy S.C., McKee M., Warner M., Gustafsson J.A., et al. Subacute exposure to low concentrations of toluene affects dopamine-mediated locomotor activity in the rat. Toxicology 1991, 67:333-349.
36. von Euler G., Ogren S.O., Eneroth P., Fuxe K., Gustafsson J.A. Persistent effects of 80ppm toluene on dopamine-regulated locomotor activity and prolactin secretion in the male rat. Neurotoxicology 1994, 15:621-624.
37. von Euler G., Ogren S.O., Li X.M., Fuxe K., Gustafsson J.A. Persistent effects of subchronic toluene exposure on spatial learning and memory, dopamine-mediated locomotor activity and dopamine D2 agonist binding in the rat. Toxicology 1993, 77:223-232.
38. von Euler M., Pham T.M., Hillefors M., Bjelke B., Henriksson B., von Euler G. Inhalation of low concentrations of toluene induces persistent effects on a learning retention task, beam-walk performance, and cerebrocortical size in the rat. Exp Neurol 2000, 163:1-8.