메뉴 건너뛰기




Volumn 21, Issue 4, 2011, Pages 301-304

Dependence of the anti-CD66 antibody biodistribution on the dissociation constant: A simulation study

Author keywords

Anti CD66 antibody; Dissociation constant; Model simulations; Radioimmunotherapy; Therapeutic index

Indexed keywords

ANTIBODY; CD66 ANTIBODY; UNCLASSIFIED DRUG;

EID: 83255186692     PISSN: 09393889     EISSN: 18764436     Source Type: Journal    
DOI: 10.1016/j.zemedi.2011.03.003     Document Type: Article
Times cited : (5)

References (13)
  • 1
    • 24944479163 scopus 로고    scopus 로고
    • 90Y-labelled anti-CD66 antibody as part of a dose-reduced conditioning regimen for patients with acute leukaemia or myelodysplastic syndrome over the age of 55: results of a phase I-II study
    • 90Y-labelled anti-CD66 antibody as part of a dose-reduced conditioning regimen for patients with acute leukaemia or myelodysplastic syndrome over the age of 55: results of a phase I-II study. Br J Haematol. 2005, 130:604-613.
    • (2005) Br J Haematol. , vol.130 , pp. 604-613
    • Ringhoffer, M.1    Blumstein, N.2    Neumaier, B.3    Glatting, G.4    von Harsdorf, S.5    Buchmann, I.6
  • 2
    • 60649094346 scopus 로고    scopus 로고
    • Targeted radiotherapy in haematopoietic stem cell transplantation: results of a phase I trial using an Yttrium-90-labelled anti-CD66 murine monoclonal antibody demonstrating consistent BM targeting
    • Orchard K.H., Cooper M., Lewington V., Tristam M., Zivanovic M., Thom J. Targeted radiotherapy in haematopoietic stem cell transplantation: results of a phase I trial using an Yttrium-90-labelled anti-CD66 murine monoclonal antibody demonstrating consistent BM targeting. Bone Marrow Transplantation. 2006, 37:S45-S46.
    • (2006) Bone Marrow Transplantation. , vol.37
    • Orchard, K.H.1    Cooper, M.2    Lewington, V.3    Tristam, M.4    Zivanovic, M.5    Thom, J.6
  • 3
    • 0035437130 scopus 로고    scopus 로고
    • Rhenium 188-labeled anti-CD66 (a, b, c, e) monoclonal antibody to intensify the conditioning regimen prior to stem cell transplantation for patients with high-risk acute myeloid leukemia or myelodysplastic syndrome: results of a phase I-II study
    • Bunjes D., Buchmann I., Duncker C., Seitz U., Kotzerke J., Wiesneth M. Rhenium 188-labeled anti-CD66 (a, b, c, e) monoclonal antibody to intensify the conditioning regimen prior to stem cell transplantation for patients with high-risk acute myeloid leukemia or myelodysplastic syndrome: results of a phase I-II study. Blood. 2001, 98:565-572.
    • (2001) Blood. , vol.98 , pp. 565-572
    • Bunjes, D.1    Buchmann, I.2    Duncker, C.3    Seitz, U.4    Kotzerke, J.5    Wiesneth, M.6
  • 4
    • 77950348118 scopus 로고    scopus 로고
    • Radioimmunotherapy with anti-CD66 antibody: Improving the biodistribution using a physiologically based pharmacokinetic model
    • Kletting P., Kull T., Bunjes D., Mahren B., Luster M., Reske S.N. Radioimmunotherapy with anti-CD66 antibody: Improving the biodistribution using a physiologically based pharmacokinetic model. J Nucl Med. 2010, 51:484-491.
    • (2010) J Nucl Med. , vol.51 , pp. 484-491
    • Kletting, P.1    Kull, T.2    Bunjes, D.3    Mahren, B.4    Luster, M.5    Reske, S.N.6
  • 5
    • 0024413549 scopus 로고
    • Effect of dose, molecular size, affinity, and protein binding on tumor uptake of antibody or ligand: a biomathematical model
    • Thomas G.D., Chappell M.J., Dykes P.W., Ramsden D.B., Godfrey K.R., Ellis J.R. Effect of dose, molecular size, affinity, and protein binding on tumor uptake of antibody or ligand: a biomathematical model. Cancer Res. 1989, 49:3290-3296.
    • (1989) Cancer Res. , vol.49 , pp. 3290-3296
    • Thomas, G.D.1    Chappell, M.J.2    Dykes, P.W.3    Ramsden, D.B.4    Godfrey, K.R.5    Ellis, J.R.6
  • 6
    • 59249089861 scopus 로고    scopus 로고
    • Improving anti-CD45 antibody radioimmunotherapy using a physiologically based pharmacokinetic model
    • Kletting P., Bunjes D., Reske S.N., Glatting G. Improving anti-CD45 antibody radioimmunotherapy using a physiologically based pharmacokinetic model. J Nucl Med. 2009, 50:296-302.
    • (2009) J Nucl Med. , vol.50 , pp. 296-302
    • Kletting, P.1    Bunjes, D.2    Reske, S.N.3    Glatting, G.4
  • 7
    • 34447330544 scopus 로고    scopus 로고
    • Whole-body physiologically based pharmacokinetic models
    • Nestorov I. Whole-body physiologically based pharmacokinetic models. Expert Opin Drug Metab Toxicol. 2007, 3:235-249.
    • (2007) Expert Opin Drug Metab Toxicol. , vol.3 , pp. 235-249
    • Nestorov, I.1
  • 8
    • 0026705890 scopus 로고
    • Effect of Bivalent Interaction upon Apparent Antibody Affinity: Experimental Confirmation of Theory Using Fluorescence Photobleaching and Implications for Antibody Binding Assays
    • Kaufman E.N., Jain R.K. Effect of Bivalent Interaction upon Apparent Antibody Affinity: Experimental Confirmation of Theory Using Fluorescence Photobleaching and Implications for Antibody Binding Assays. Cancer Res. 1992, 52:4157-4167.
    • (1992) Cancer Res. , vol.52 , pp. 4157-4167
    • Kaufman, E.N.1    Jain, R.K.2
  • 9
    • 0031940813 scopus 로고    scopus 로고
    • SAAM II: Simulation, Analysis, and Modeling Software for tracer and pharmacokinetic studies
    • Barrett P.H., Bell B.M., Cobelli C., Golde H., Schumitzky A., Vicini P. SAAM II: Simulation, Analysis, and Modeling Software for tracer and pharmacokinetic studies. Metabolism. 1998, 47:484-492.
    • (1998) Metabolism. , vol.47 , pp. 484-492
    • Barrett, P.H.1    Bell, B.M.2    Cobelli, C.3    Golde, H.4    Schumitzky, A.5    Vicini, P.6
  • 10
    • 0021984583 scopus 로고
    • Interaction of monoclonal antibodies with MHC class I antigens on mouse spleen cells. II. Levels of expression of H-2K, H-2D, and H-2L in different mouse strains
    • Dower S.K., Segal D.M. Interaction of monoclonal antibodies with MHC class I antigens on mouse spleen cells. II. Levels of expression of H-2K, H-2D, and H-2L in different mouse strains. J Immunol. 1985, 134:431-435.
    • (1985) J Immunol. , vol.134 , pp. 431-435
    • Dower, S.K.1    Segal, D.M.2
  • 11
    • 0027366723 scopus 로고
    • Re-evaluation of the concept of functional affinity as applied to bivalent antibody binding to cell surface antigens
    • Ong G.L., Mattes M.J. Re-evaluation of the concept of functional affinity as applied to bivalent antibody binding to cell surface antigens. Mol Immunol. 1993, 30:1455-1462.
    • (1993) Mol Immunol. , vol.30 , pp. 1455-1462
    • Ong, G.L.1    Mattes, M.J.2
  • 12
    • 0026609610 scopus 로고
    • Bindung des monoklonalen Antikörpers BW 250/183 an menschliche Granulozyten [Binding of Monoclonal Antibody BW 250/183 to Human Granulocytes]
    • Steinsträßer A., Berberich R., Kuhlmann L., Zabori S., Schwarz A. Bindung des monoklonalen Antikörpers BW 250/183 an menschliche Granulozyten [Binding of Monoclonal Antibody BW 250/183 to Human Granulocytes]. Nuklearmedizin. 1992, 31:57-63.
    • (1992) Nuklearmedizin. , vol.31 , pp. 57-63
    • Steinsträßer, A.1    Berberich, R.2    Kuhlmann, L.3    Zabori, S.4    Schwarz, A.5
  • 13
    • 65649104119 scopus 로고    scopus 로고
    • Antibodies for therapeutic uses and the evolution of biotechniques
    • Nieri P., Donadio E., Rossi S., Adinolfi B., Podesta A. Antibodies for therapeutic uses and the evolution of biotechniques. Curr Med Chem. 2009, 16:753-779.
    • (2009) Curr Med Chem. , vol.16 , pp. 753-779
    • Nieri, P.1    Donadio, E.2    Rossi, S.3    Adinolfi, B.4    Podesta, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.