Compositional optimization and safety assessment of a hydrogel patch as a transcutaneous immunization device

Biological and Pharmaceutical Bulletin

Volumn 34, Issue 12, 2011, Pages 1835-1840

  Matsuo, Kazuhiko ^a   Ishii, Yumiko ^a   Quan, Ying Shu ^b   Kamiyama, Fumio ^b   Asada, Hideo ^c   Mukai, Yohei ^a   Okada, Naoki ^a   Nakagawa, Shinsaku ^a  

^a OSAKA UNIVERSITY   (Japan)

^b CosMED Pharmaceuticals Co Ltd ^*  (Japan)

^c NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Composition; Hydrogel patch; Safety; Skin hydration; Transcutaneous immunization

Indexed keywords

DIPHTHERIA TOXOID; OVALBUMIN; TETANUS TOXOID; WATER;

ADVERSE DRUG REACTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; DEVICE SAFETY; DEVICES; DRUG DELIVERY SYSTEM; FEMALE; HYDRATION; HYDROGEL; IMMUNE RESPONSE; MALE; MOISTURE; NONHUMAN; RAT; SKIN PENETRATION; STRATUM CORNEUM; SYSTEMIC DISEASE; TRANSCUTANEOUS IMMUNIZATION DEVICE; TRANSDERMAL PATCH; WATER CONTENT;

EID: 83255162005     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.34.1835     Document Type: Article

References (15)

1. Kersten G., Hirschberg H., Expert Opin. Drug Deliv., 4, 459-474 (2007).
2. Azad N., Rojanasakul Y., Curr. Drug Deliv., 3, 137-146 (2006).
3. Berger C. L., Vasquez J. G., Shofner J., Mariwalla K., Edelson R. L., Int. J. Biochem. Cell Biol., 38, 1632-1636 (2006).
4. Sugita K., Kabashima K., Atarashi K., Shimauchi T., Kobayashi M., Tokura Y., Clin. Exp. Immunol., 147, 176-183 (2007).
5. Mathers A. R., Larregina A. T., Immunol. Res., 36, 127-136 (2006).
6. Metz M., Siebenhaar F., Maurer M., Immunobiology, 213, 251-260 (2008).
7. Goodarzi H., Trowbridge J., Gallo R. L., Clin. Rev. Allergy Immunol., 33, 15-26 (2007).
8. Barry B. W., Nat. Biotechnol., 22, 165-167 (2004).
9. Ishii Y., Nakae T., Sakamoto F., Matsuo K., Matsuo K., Quan Y. S., Kamiyama F., Fujita T., Yamamoto A., Nakagawa S., Okada N., J. Controlled Release, 131, 113-120 (2008).
10. Matsuo K., Ishii Y., Quan Y. S., Kamiyama F., Mukai Y., Yoshioka Y., Okada N., Nakagawa S., J. Controlled Release, 149, 15-20 (2011).
11. Kinnen E., Med. Electron. Biol. Eng., 3, 67-70 (1965).
12. Draize J. H., Woodard G., Calvery H. O., J. Pharmacol. Exp. Ther., 82, 377-390 (1944).
13. Naito S., Maeyama J., Mizukami T., Takahashi M., Hamaguchi I., Yamaguchi K., Vaccine, 25, 8762-8770 (2007).
14. Edelberg R., J. Invest. Dermatol., 69, 324-327 (1977).
15. Alonso A., Meirelles N. C., Yushmanov V. E., Tabak M., J. Invest. Dermatol., 106, 1058-1063 (1996).