Long-term effects of chlorthalidone versus hydrochlorothiazide on electrocardiographic left ventricular hypertrophy in the Multiple Risk Factor Intervention Trial

Hypertension

Volumn 58, Issue 6, 2011, Pages 1001-1007

  Ernst, Michael E ^a,b   Neaton, James D ^c   Grimm, Richard H ^d   Collins, Gary ^c   Thomas, William ^c   Soliman, Elsayed Z ^e   Prineas, Ronald J ^e  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^e WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Blood pressure; Chlorthalidone; Electrocardiography; Hydrochlorothiazide; HYPERTENSION; Left ventricular hypertrophy

Indexed keywords

ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHLORTALIDONE; GUANETHIDINE; HYDROCHLOROTHIAZIDE;

ADULT; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DRUG EFFECT; ELECTROCARDIOGRAPHY; FOLLOW UP; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; SODIUM RESTRICTION; WEIGHT REDUCTION;

ADULT; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CHLORTHALIDONE; COMBINED MODALITY THERAPY; DIURETICS; ELECTROCARDIOGRAPHY; FOLLOW-UP STUDIES; HUMANS; HYDROCHLOROTHIAZIDE; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; INTERVENTION STUDIES; MALE; MIDDLE AGED; MULTICENTER STUDIES AS TOPIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS; TREATMENT OUTCOME;

EID: 83155180324     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.181248     Document Type: Article

References (21)

1. Ernst ME, Moser M. Use of diuretics in patients with hypertension. N Engl J Med. 2009;361:2153-2164.
2. Ernst ME, Lund BC. Renewed interest in chlorthalidone: evidence from the Veterans Health Administration. J Clin Hypertens (Greenwich). 2010;12:927-934.
3. Multiple Risk Factor Intervention Trial Research Group. Multiple Risk Factor Intervention Trial: risk factor changes and mortality results. JAMA. 1982;248:1465-1477.
4. Multiple Risk Factor Intervention Trial Research Group. Mortality after 10 1/2 years for hypertensive participants in the Multiple Risk Factor Intervention Trial. Circulation. 1990;82:1616-1628.
5. Bartsch G, Broste S, Grandits G, Grimm RH, Neaton JD, Svendsen KH. Hydrochlorothiazide, chlorthalidone and mortality in the Multiple Risk Factor Intervention Trial [abstract]. Circulation. 1984;70(suppl II): 1438.
6. Ernst ME, Carter BL, Goerdt CJ, Steffensmeier JJ, Phillips BB, Zimmerman MB, Bergus GR. Comparative antihypertensive effects of hydrochlorothiazide and chlorthalidone on ambulatory and office blood pressure. Hypertension. 2006;47:352-358.
7. Bacharova L, Estes H, Bang L, Rowlandson I, Schillaci G, Verdecchia P, Macfarlane PW. The first statement of the Working Group on Electrocardiographic Diagnosis of Left Ventricular Hypertrophy. J Electrocardiol. 2010;43:197-199.
8. Hsieh BP, Pham MX, Froelicher VF. Prognostic value of electrocardiographic criteria for left ventricular hypertrophy. Am Heart J. 2005;150:161-167.
9. Jain A, Tandri H, Dalal D, Chahal H, Soliman EZ, Prineas RJ, Folsom AR, Lima JA, Bluemke DA. Diagnostic and prognostic utility of electrocardiography for left ventricular hypertrophy defined by magnetic resonance imaging in relationship to ethnicity: the Multi-Ethnic Study of Atherosclerosis (MESA). Am Heart J. 2010;159:652-658.
10. Cohen JD, Grimm RH, Smith WM. Multiple Risk Factor Intervention Trial: VI-intervention on blood pressure. Prev Med. 1981;10:501-518.
11. Wolf H, MacInnis PJ, Stock S, Helppi RK, Rautaharju PM. The Dalhousie Program: a comprehensive analysis program for rest and exercise electrocardiograms. In: Zwietz C, Schneider B, eds. Computer Application on ECG and VCG Analysis. Amsterdam, the Netherlands: North-Holland Publishing; 1973:231-288.
12. Multiple Risk Factor Intervention Trial Research Group. Baseline rest electrocardiographic abnormalities, antihypertensive treatment and mortality in the Multiple Risk Factor Intervention Trial. Am J Cardiol. 1985;55:1-15.
13. MacMahon S, Collins G, Rautaharju P, Cutler J, Neaton J, Prineas R, Crow R, Stamler J, for the Multiple Risk Factor Intervention Trial Research Group. Electrocardiographic left ventricular hypertrophy and effects of antihypertensive drug therapy in hypertensive participants in the Multiple Risk Factor Intervention Trial. Am J Cardiol. 1989;63:202-210.
14. Crow RS, Prineas RJ, Hannan PJ, Grandits G, Blackburn H. Prognostic associations of Minnesota code serial electrocardiographic change classification with coronary heart disease mortality in the Multiple Risk Factor Intervention Trial. Am J Cardiol. 1997;80:138-144.
15. Prineas RJ, Rautaharju PM, Grandits G, Crow R, for the MRFIT Research Group. Independent risk for cardiovascular disease predicted by modified continuous score electrocardiographic criteria for 6-year incidence and regression of left ventricular hypertrophy among clinically disease free men: 16-year follow-up for the Multiple Risk Factor Intervention Trial. J Electrocardiol. 2001;34:91-101.
16. Sokolow M, Lyon T. Ventricular complex in left ventricular hypertrophy as obtained by unipolar precordial and limb leads. Am Heart J. 1949;37:161-186.
17. Molloy TJ, Okin PM, Devereux RB, Kligfield P. Electrocardiographic detection of left ventricular hypertrophy by the simple QRS voltageduration product. J Am Coll Cardiol. 1992;20:1180-1186.
18. Rautaharju PM, Park LP, Gottdiener JS. Race-and sex-specific ECG models for left ventricular mass in older populations: factors influencing overestimation of left ventricular hypertrophy prevalence by ECG criteria in African-Americans. J Electrocardiol. 2000;33:205-218.
19. Hancock EW, Deal BJ, Mirvis DM, Okin P, Kligfield P, Gettes LS. AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part V-electrocardiogram changes associated with cardiac chamber hypertrophy: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee; Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society-endorsed by the International Society for Computerized Electrocardiology. J Am Coll Cardiol. 2009;53:992-1002.
20. Morgenstern H. Uses of ecologic analysis in epidemiologic research. Am J Public Health. 1982;72:1336-1344.
21. Dorsch MP, Gillespie BW, Erickson SR, Bleske BE, Weder AB. Chlorthalidone reduces cardiovascular events compared with hydrochlorothiazide: a retrospective cohort analysis. Hypertension. 2011;57:689-694.