-
2
-
-
47649125502
-
RAS blockade with ARB and ACE inhibitors: Current perspective on rationale and patient selection
-
Werner C, Baumhakel M, Teo KK, et al. RAS blockade with ARB and ACE inhibitors: current perspective on rationale and patient selection. Clin Res Cardiol. 2008;97:418-431.
-
(2008)
Clin Res Cardiol
, vol.97
, pp. 418-431
-
-
Werner, C.1
Baumhakel, M.2
Teo, K.K.3
-
3
-
-
52649099445
-
Cardiovascular protection for all individuals at high risk: Evidence-based best practice
-
Bakris G, Böhm M, Dagenais G, et al. Cardiovascular protection for all individuals at high risk: evidence-based best practice. Clin Res Cardiol. 2008;97:713-725.
-
(2008)
Clin Res Cardiol
, vol.97
, pp. 713-725
-
-
Bakris, G.1
Böhm, M.2
Dagenais, G.3
-
4
-
-
33144462795
-
ACE inhibition in secondary prevention: Are the results controversial?
-
Friedrich EB, Teo KK, Böhm M. ACE inhibition in secondary prevention: are the results controversial? Clin Res Cardiol. 2006;95: 61-67.
-
(2006)
Clin Res Cardiol
, vol.95
, pp. 61-67
-
-
Friedrich, E.B.1
Teo, K.K.2
Böhm, M.3
-
5
-
-
71449119982
-
Telmisartan prevents cardiovascular events in a broad group of at-risk patients
-
Baumhakel M, Böhm M. Telmisartan prevents cardiovascular events in a broad group of at-risk patients. Expert Opin Pharmacother. 2009; 10:3113-3117.
-
(2009)
Expert Opin Pharmacother
, vol.10
, pp. 3113-3117
-
-
Baumhakel, M.1
Böhm, M.2
-
6
-
-
0037154324
-
The AT(1)-type angiotensin receptor in oxidative stress and atherogenesis: Part I. Oxidative stress and atherogenesis
-
Nickenig G, Harrison DG. The AT(1)-type angiotensin receptor in oxidative stress and atherogenesis: part I. Oxidative stress and atherogenesis. Circulation. 2002;105:393-396.
-
(2002)
Circulation
, vol.105
, pp. 393-396
-
-
Nickenig, G.1
Harrison, D.G.2
-
7
-
-
33845902544
-
The cardiovascular disease continuum validated: Clinical evidence of improved patient outcomes. Part I. Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease)
-
Dzau VJ, Antman EM, Black HR, et al. The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes. Part I. Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease). Circulation. 2006;114:2850-2870.
-
(2006)
Circulation
, vol.114
, pp. 2850-2870
-
-
Dzau, V.J.1
Antman, E.M.2
Black, H.R.3
-
8
-
-
0037160968
-
LIFE Study Group. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
-
Dahlöf B, Devereux RB, Kjeldsen SE, et al. LIFE Study Group. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet. 2002;359:995-1003.
-
(2002)
Lancet
, vol.359
, pp. 995-1003
-
-
Dahlöf, B.1
Devereux, R.B.2
Kjeldsen, S.E.3
-
9
-
-
34250350040
-
2007 guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
-
Mancia G, De Backer G, Dominiczak A, et al. 2007 guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens. 2007;25:1105-1187.
-
(2007)
J Hypertens
, vol.25
, pp. 1105-1187
-
-
Mancia, G.1
de Backer, G.2
Dominiczak, A.3
-
10
-
-
2942635317
-
Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: The VALUE randomised trial
-
Julius S, Kjeldsen SE, Weber M, et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet. 2004; 363:2022-2031.
-
(2004)
Lancet
, vol.363
, pp. 2022-2031
-
-
Julius, S.1
Kjeldsen, S.E.2
Weber, M.3
-
11
-
-
73849084830
-
Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO Heart Study
-
Sawada T, Yamada H, Dahlof B, et al. Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO Heart Study. Eur Heart J. 2009;30: 2461-2469.
-
(2009)
Eur Heart J
, vol.30
, pp. 2461-2469
-
-
Sawada, T.1
Yamada, H.2
Dahlof, B.3
-
12
-
-
0242284429
-
-
International Diabetes Federation, 3rd ed, Available at, Accessed June 2, 2010
-
International Diabetes Federation. The Diabetes Atlas. 3rd ed, 2006. Available at: http://www.eatlas.idf.org. Accessed June 2, 2010.
-
(2006)
The Diabetes Atlas
-
-
-
13
-
-
42049107348
-
Telmisartan, ramipril, or both in patients at high risk for vascular events
-
Yusuf S, Teo KK, Pogue J, et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med. 2008;358:1547-1559.
-
(2008)
N Engl J Med
, vol.358
, pp. 1547-1559
-
-
Yusuf, S.1
Teo, K.K.2
Pogue, J.3
-
14
-
-
0034688194
-
Effects of an angiotensinconverting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
-
Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensinconverting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342:145-153.
-
(2000)
N Engl J Med
, vol.342
, pp. 145-153
-
-
Yusuf, S.1
Sleight, P.2
Pogue, J.3
-
15
-
-
53049109468
-
Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: A randomised controlled trial
-
Yusuf S, Teo K, Anderson C, et al. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. Lancet. 2008;372:1174-1183.
-
(2008)
Lancet
, vol.372
, pp. 1174-1183
-
-
Yusuf, S.1
Teo, K.2
Anderson, C.3
-
16
-
-
3142740224
-
Rationale, design, and baseline characteristics of 2 large, simple, randomized trials evaluating telmisartan, ramipril, and their combination in high-risk patients: The Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial/Telmisartan Randomized Assessment Study in ACE Intolerant Subjects with Cardiovascular Disease. (ONTARGET®/ TRANSCEND®) trials
-
Teo K, Yusuf S, Anderson C, et al. Rationale, design, and baseline characteristics of 2 large, simple, randomized trials evaluating telmisartan, ramipril, and their combination in high-risk patients: the Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial/Telmisartan Randomized Assessment Study in ACE Intolerant Subjects with Cardiovascular Disease. (ONTARGET®/ TRANSCEND®) trials. Am Heart J. 2004;148:52-61.
-
(2004)
Am Heart J
, vol.148
, pp. 52-61
-
-
Teo, K.1
Yusuf, S.2
Anderson, C.3
-
17
-
-
79952373965
-
Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes
-
Haller H, Ito S, Izzo JL, et al. Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes. N Engl J Med. 2011;364: 907-917.
-
(2011)
N Engl J Med
, vol.364
, pp. 907-917
-
-
Haller, H.1
Ito, S.2
Izzo, J.L.3
-
18
-
-
84862556665
-
-
Food and Drug Administration, June 11, Available at, Accessed April 5, 2011
-
Food and Drug Administration. FDA drug safety communication: ongoing safety review of Benicar and cardiovascular events. June 11, 2010. Available at: http://www.fda.gov/Drugs/DrugSafety/Post marketDrugSafetyInformationforPatientsandProviders/ucm215222. htm. Accessed April 5, 2011.
-
(2010)
FDA drug safety communication: Ongoing safety review of Benicar and cardiovascular events
-
-
-
19
-
-
33746088001
-
Trends in prevalence and outcome of heart failure with preserved ejection fraction
-
Owan TE, Hodge DO, Herges RM, et al. Trends in prevalence and outcome of heart failure with preserved ejection fraction. N Engl J Med. 2006;355:251-259.
-
(2006)
N Engl J Med
, vol.355
, pp. 251-259
-
-
Owan, T.E.1
Hodge, D.O.2
Herges, R.M.3
-
20
-
-
0242490542
-
Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
-
Pfeffer MA, McMurray JJ, Velazquez EJ, et al. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med. 2003;349:1893-1906.
-
(2003)
N Engl J Med
, vol.349
, pp. 1893-1906
-
-
Pfeffer, M.A.1
McMurray, J.J.2
Velazquez, E.J.3
-
21
-
-
0037036971
-
Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: The OPTIMAAL randomised trial
-
OPTIMAAL steering committee
-
Dickstein K, Kjekshus J; OPTIMAAL steering committee. Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial. Lancet. 2002;360:752-760.
-
(2002)
Lancet
, vol.360
, pp. 752-760
-
-
Dickstein, K.1
Kjekshus, J.2
-
22
-
-
0034612118
-
Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: Randomised trial-the Losartan Heart Failure Survival Study ELITE II
-
Pitt B, Poole-Wilson P, Segal R, et al. Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial-the Losartan Heart Failure Survival Study ELITE II. Lancet. 2000;355:1582-1587.
-
(2000)
Lancet
, vol.355
, pp. 1582-1587
-
-
Pitt, B.1
Poole-Wilson, P.2
Segal, R.3
-
23
-
-
71549127400
-
Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): A randomised, double-blind trial
-
Konstam MA, Neaton JD, Dickstein K, et al. Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial. Lancet. 2009;374:1840-1848.
-
(2009)
Lancet
, vol.374
, pp. 1840-1848
-
-
Konstam, M.A.1
Neaton, J.D.2
Dickstein, K.3
-
24
-
-
0041408234
-
Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: The CHARM-Preserved Trial
-
Yusuf S, Pfeffer MA, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet. 2003;362:777-781.
-
(2003)
Lancet
, vol.362
, pp. 777-781
-
-
Yusuf, S.1
Pfeffer, M.A.2
Swedberg, K.3
-
25
-
-
57349142933
-
Irbesartan in patients with heart failure and preserved ejection fraction
-
Massie BM, Carson PE, McMurray JJ, et al. Irbesartan in patients with heart failure and preserved ejection fraction. N Engl J Med. 2008; 359:2456-2467.
-
(2008)
N Engl J Med
, vol.359
, pp. 2456-2467
-
-
Massie, B.M.1
Carson, P.E.2
McMurray, J.J.3
-
26
-
-
78349252300
-
Effects of telmisartan added to angiotensin-converting enzyme inhibitors on mortality and morbidity in hemodialysis patients with chronic heart failure: A double-blind, placebo-controlled trial
-
Cice G, Di Benedetto A, D'Isa S, et al. Effects of telmisartan added to angiotensin-converting enzyme inhibitors on mortality and morbidity in hemodialysis patients with chronic heart failure: a double-blind, placebo-controlled trial. J Am Coll Cardiol. 2010;56:1701-1708.
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 1701-1708
-
-
Cice, G.1
Di Benedetto, A.2
D'Isa, S.3
-
27
-
-
77954030665
-
Angiotensin-receptor blockade and risk of cancer: Meta-analysis of randomized controlled trials
-
Sipahi I, Debanne SM, Rowland DY, et al. Angiotensin-receptor blockade and risk of cancer: meta-analysis of randomized controlled trials. Lancet Oncol. 2010;11:627-636.
-
(2010)
Lancet Oncol
, vol.11
, pp. 627-636
-
-
Sipahi, I.1
Debanne, S.M.2
Rowland, D.Y.3
-
28
-
-
77956139243
-
Angiotensin-receptor blockade and the risk of cancer. Omission of VALUE trial data invalidates conclusions
-
Julius S, Kjeldsen S, Weber M. Angiotensin-receptor blockade and the risk of cancer. Omission of VALUE trial data invalidates conclusions. Lancet Oncol. 2010;11:820-821.
-
(2010)
Lancet Oncol
, vol.11
, pp. 820-821
-
-
Julius, S.1
Kjeldsen, S.2
Weber, M.3
-
29
-
-
79952774764
-
Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138 769 individuals
-
The ARB Trialists Collaboration
-
The ARB Trialists Collaboration. Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138 769 individuals. J Hypertens. 2011;29:623-635.
-
(2011)
J Hypertens
, vol.29
, pp. 623-635
-
-
-
30
-
-
0035818884
-
A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
-
Valsartan Heart Failure Trial Investigators
-
Cohn JN, Tognoni G; Valsartan Heart Failure Trial Investigators. A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med. 2001;345:1667-1675.
-
(2001)
N Engl J Med
, vol.345
, pp. 1667-1675
-
-
Cohn, J.N.1
Tognoni, G.2
-
31
-
-
0041408235
-
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-Added trial
-
McMurray JJ, Ostergren J, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet. 2003;362:767-771.
-
(2003)
Lancet
, vol.362
, pp. 767-771
-
-
McMurray, J.J.1
Ostergren, J.2
Swedberg, K.3
|