Chronic psychosocial stress induces reversible mitochondrial damage and corticotropin-releasing factor receptor type-1 upregulation in the rat intestine and IBS-like gut dysfunction

Psychoneuroendocrinology

Volumn 37, Issue 1, 2012, Pages 65-77

  Vicario, María ^a   Alonso, Carmen ^a   Guilarte, Mar ^a   Serra, Jordi ^a   Martínez, Cristina ^a   González Castro, Ana M ^a   Lobo, Beatriz ^a   Antolín, María ^a   Andreu, Antoni L ^b   García Arumí, Elena ^b   Casellas, Montserrat ^a   Saperas, Esteban ^a   Malagelada, Juan Ramón ^a   Azpiroz, Fernando ^a   Santos, Javier ^a  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

Author keywords

Intestinal dysfunction; Irritable bowel syndrome; Mitochondrial function; Psychosocial stress

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC PSYCHOSOCIAL STRESS; CHRONIC STRESS; CONTROLLED STUDY; CORRELATION ANALYSIS; CROWDING; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EPITHELIAL ION TRANSPORT; HORMONE RESPONSE; HYPERALGESIA; HYPERSENSITIVITY; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INTESTINE; INTESTINE MUCOSA PERMEABILITY; ION TRANSPORT; IRRITABLE COLON; MUCOSA INFLAMMATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION; VISCERAL HYPERSENSITIVITY; WEIGHT GAIN;

ANIMALS; BODY WEIGHT; COLON; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; CROWDING; DEFECATION; DISEASE MODELS, ANIMAL; HUMANS; HYPERALGESIA; INFLAMMATION; INTESTINAL MUCOSA; IRRITABLE BOWEL SYNDROME; MALE; MITOCHONDRIA; RATS; RATS, INBRED WKY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; STRESS, PSYCHOLOGICAL; UP-REGULATION;

EID: 83055188385     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2011.05.005     Document Type: Article

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