Structure activity relationship studies of substituted Mannich bases of 2-oxo-4, 6-diphenyl-2, 6-dihydropyrazolo [1,5-a] [1,3,5] triazine-7-carbonyl ring system with variable electronegetive atoms (urea/thiourea/guanidine) for antimicrobial and antifungal activity

International Journal of Drug Development and Research

Volumn 3, Issue 2, 2011, Pages 334-343

  Modi, Kaumil Navnitbhai ^a   Panchal, Sanjay D ^a   Sen, Dhrubo Jyoti ^a  

^a GUJARAT TECHNOLOGICAL UNIVERSITY   (India)

Author keywords

Antibacterial; Antifungal; Benzoylation; Pyrazolo triazine

Indexed keywords

2 OXO 4,6 DIPHENYL 2,6 DIHYDROPYRAZOLO[1,5 A][1,3,5]TRIAZINE 7 CARBONYL RING; 7 METHYL 4,6 DIPHENYLPYRAZOLO[1,5 A][1,3,5]TRIAZIN 2 (6H)ONE; ACETYLPHENYLHYDRAZINE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; BENZALDEHYDE; BENZYL DERIVATIVE; CARBONYL DERIVATIVE; GUANIDINE; MANNICH BASE; NITROGEN; OXYGEN; PYRAZOLONE; SULFUR; THIOUREA; UNCLASSIFIED DRUG; UREA;

ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; CANDIDA ALBICANS; DRUG SYNTHESIS; ESCHERICHIA COLI; NONHUMAN; OXIDATION; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

EID: 83055174073     PISSN: None     EISSN: 09759344     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Dhrubo Jyoti Sen; Investigation on newer antiinflammatory, sedative-hypnotic & antimicrobial agents: Indian Journal of Pharmaceutical Education: 35 (4), 178, 2001.
2. Latha, S., Selvamani, P., Sen, D.J., Gupta, J.K., Pal, T.K. and Ghosh, L.K.; Antibacterial activity of Commiphora caudata and Commiphora berryi leaves: Indian Drugs: 42(10), 696-698, 2005.
3. Karad, R., Vyas, R., Sen D.J. and Patel, C.N.; Antimicrobial screening of Caesalpinia crista seeds: Journal of Advances in Biological Sciences: 4, 87-89, 2005.
4. Dhaval M. Patel and Dr. Dhrubo Jyoti Sen; Synthesis and antimicrobial screening by SAR studies of synthesized chalcone derivatives having heterocyclic rings: International Journal of Pharmaceutical Sciences; 1(1), 35-41, 2009.
5. Maulik K. Prajapati and Dr. Dhrubo Jyoti Sen; Synthesis and SAR study of some new 2-Imino-3- [carboxamido p-hydroxyphenyl]-5-arylidene-4- thiazolidinone as antimicrobial agents: International Journal of Pharmaceutical Sciences; 1(1), 83-90, 2009.
6. Parimal M. Prajapati and Prof. Dr. Dhrubo Jyoti Sen; Synthesis and antimicrobial screening of piperidone derivative with pyrazolone substituents: The Manufacturing Pharmacist; 02(07), 37-44, 2010.
7. Hiren R. Patel, Parth K. Patel, Dhrubo Jyoti Sen and Amit H. Patel; Growth inhibition of microorganism by bioisosterism: International Journal of Drug Development and Research; 2(1), 190-196, 2010.
8. Avani Sheth, Naman Doshi, D. J. Sen, R. Badmanaban, C. N. Patel; Synthesis of picric acid & para amino phenol derivatives for anti-microbial activity: Journal of Chemical and Pharmaceutical Research; 2(2), 1-12, 2010.
9. Vijay K Patel, Dhrubo Jyoti Sen and C. N. Patel; Antimicrobial and antifungal screening of indanone acetic acid derivatives: Journal of Chemical and Pharmaceutical Research; 2(2), 50-56, 2010.
10. Parimal M. Prajapati, Dhrubo Jyoti Sen and C N Patel; Synthesis and antifungal screening of piperidone derivative with pyrazolone substituents: Journal of Chemical and Pharmaceutical Research; 2(2), 279-285, 2010.
11. Yatri R. Shah, Dhrubo Jyoti Sen and C.N. Patel; Schiff's bases of piperidone derivative as microbial growth inhibitors: Journal of Chemical and Pharmaceutical Research; 2(2), 581-589, 2010.
12. Yatri R. Shah and Prof. Dr. Dhrubo Jyoti Sen; Schiff's bases of piperidone derivatives as fungal growth inhibitors: The Manufacturing Pharmacist; 02(09), 37-44, 2010.
13. Dhrubo Jyoti Sen, Palakben K. Parikh, Julee P. Soni, Kaumil N. Modi, Hiren M. Marvaniya, Priya R. Modiya, Apexa D. Patel, Dilip R. Chavda, Deepa R. Parmar, Sanjay D. Panchal and Vidhi R. Patel; Lead identification by structure activity relationship study of schiff bases of 3-amino-2-methyl quinazolin 4-(3H)-one for antimicrobial and antifungal activity: International Journal of Pharmacology and Technology; 2(1), 37-43, 2010.
14. Dhrubo Jyoti Sen, Palakben K. Parikh, Julee P. Soni, Kaumil N. Modi, Hiren M. Marvaniya, Priya R. Modiya, Apexa D. Patel, Dilip R. Chavda, Deepa R. Parmar, Sanjay D. Panchal and Vidhi R. Patel; Antibacterial screening of synthesised 5-methyl-N΄-[(1E)-phenylmethylene]-pyrazine-2-carbohydrazide derivatives by zone of inhibition study and MIC: International Journal of Drug Targets; 1(1), 47-56, 2010.
15. Ravi Natvarlal Patel, Urviben Yashodharbhai Patel, Ripal R. Chaudhari and Prof. Dr. Dhrubo Jyoti Sen; Synthesis and antibacterial study of some new schiff's bases of 2-hydrazinyl-1-(1H-imidazole-1-yl)-ethanone: Asian Journal of Research in Chemistry; 4(1), 55-57, 2011.
16. Vikramkumar Vishnubhai Patel and Prof Dr Dhrubo Jyoti Sen; Synthesis of substituted triazolo-pyrrole fused ring adduct with benzylidene piperidyl urea/thiourea bridge and screening for CNS depression: International Journal of Drug Development and Research: 2(1), 203-210, 2010.