LC-MS/MS analysis of neonicotinoid insecticides in honey: Methodology and residue findings in Austrian honeys

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 23, 2011, Pages 12271-12277

  Tanner, Gina ^a,b   Czerwenka, Christoph ^a  

^a AUSTRIAN AGENCY FOR HEALTH AND FOOD SAFETY   (Austria)

^b Research Station Agroscope Liebefeld Posieux ALP   (Switzerland)

Author keywords

honey; LC MS MS; Neonicotinoid insecticides; pesticide residues; QuEChERS

Indexed keywords

HONEY; LC-MS/MS; NEONICOTINOID INSECTICIDES; PESTICIDE RESIDUES; QUECHERS;

ACETONITRILE; INSECT CONTROL; INSECTICIDES;

FOOD PRODUCTS;

ACETAMIPRID; ANABASINE; INSECTICIDE; NITRO DERIVATIVE; OXAZINE DERIVATIVE; PESTICIDE RESIDUE; PYRIDINE DERIVATIVE; THIACLOPRID; THIAMETHOXAM; THIAZINE DERIVATIVE; THIAZOLE DERIVATIVE;

ARTICLE; AUSTRIA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HONEY; METHODOLOGY; TANDEM MASS SPECTROMETRY;

ANABASINE; AUSTRIA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HONEY; INSECTICIDES; NITRO COMPOUNDS; OXAZINES; PESTICIDE RESIDUES; PYRIDINES; TANDEM MASS SPECTROMETRY; THIAZINES; THIAZOLES;

EID: 83055165753     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf202775m     Document Type: Article

References (21)

1. Schäfer, B. Nicotin und die Neonicotinoide-Teil 2 Die Neonicotinoide Chem. Unserer Zeit 2008, 42, 408-424
2. Sun, C.; Yang, D.; Xing, J.; Wang, H.; Jin, J.; Zhu, J. Nitromethylene neonicotinoids analogues with tetrahydropyrimidine fixed cis-configuration: synthesis, insecticidal activities, and molecular docking studies J. Agric. Food Chem. 2010, 58, 3415-3421
3. Elbert, A.; Haas, M.; Springer, B.; Thielert, W.; Nauen, R. Applied aspects of neonicotinoid uses in crop protection Pest Manag. Sci. 2008, 64, 1099-1105
4. Fishel, F. M. Pesticide toxicity profile: neonicotinoid pesticides, University of Florida; http://edis.ifas.ufl.edu/pi117 (Feb 9, 2011).
5. Jeschke, P.; Nauen, R. Neonicotinoids - from zero to hero in insecticide chemistry Pest Manag. Sci. 2008, 64, 1084-1098
6. Rial-Otero, R.; Gaspar, E. M.; Moura, I.; Capelo, J. L. Chromatographic-based methods for pesticide determination in honey: an overview Talanta 2007, 71, 503-514
7. Obana, H.; Okihashi, M.; Akutsu, K.; Kitagawa, Y.; Hori, S. Determination of neonicotinoid pesticide residues in vegetables and fruits with solid phase extraction and liquid chromatography mass spectrometry J. Agric. Food Chem. 2003, 51, 2501-2505
8. Di Muccio, A.; Fidente, P.; Barbini, D. A.; Dommarco, R.; Seccia, S.; Morrica, P. Application of solid-phase extraction and liquid chromatography-mass spectrometry to the determination of neonicotinoid pesticide residues in fruit and vegetables J. Chromatogr., A 2006, 1108, 1-6
9. Liu, S.; Zheng, Z.; Wei, F.; Ren, Y.; Gui, W.; Wu, H.; Zhu, G. Simultaneous determination of seven neonicotinoid pesticide residues in food by ultraperformance liquid chromatography tandem mass spectrometry J. Agric. Food Chem. 2010, 58, 3271-3278
10. Xie, W.; Han, C.; Qian, Y.; Ding, H.; Chen, X.; Xi, J. Determination of neonicotinoid pesticides residues in agricultural samples by solid-phase extraction combined with liquid chromatography-tandem mass spectrometry J. Chromatogr., A 2011, 1218, 4426-4433
11. Schöning, R.; Schmuck, R. Analytical determination of imidacloprid and relevant metabolite residues by LC-MS/MS Bull. Insectol. 2003, 56, 41-50
12. Fidente, P.; Seccia, S.; Vanni, F.; Morrica, P. Analysis of nicotinoid insecticides residues in honey by solid matrix partition clean-up and liquid chromatography-electrospray mass spectrometry J. Chromatogr., A 2005, 1094, 175-178
13. Kamel, A. Refined methodology for the determination of neonicotinoid pesticides and their metabolites in honey bees and bee products by liquid chromatography-tandem mass spectrometry (LC-MS/MS) J. Agric. Food Chem. 2010, 58, 5926-5931
14. Anastassiades, M.; Lehotay, S. J.; Štajnbaher, D.; Schenck, F. J. Fast and easy multiresidue method employing acetonitrile extraction/partitioning and dispersive solid-phase extraction for the determination of pesticide residues in produce J. AOAC Int. 2003, 86, 412-431
15. Alder, L.; Klein, J. Applicability of gradient liquid chromatography with tandem mass spectrometry to the simultaneous screening for about 100 pesticides in crops J. AOAC Int. 2003, 86, 1015-1037
16. Footprint Pesticide Properties Database; http://sitem.herts.ac.uk/aeru/ footprint/index2.htm (Feb 9, 2011).
17. Method validation and quality control procedures for pesticide residues analysis in food and feed (Document SANCO/10684/2009); http://ec.europa.eu/food/ plant/protection/resources/qualcontrol-en.pdf (Feb 9, 2011).
18. Regulation (EC) No 396/2005 of the European Parliament and of the Council of 23 February 2005 on maximum residue levels of pesticides in or on food and feed of plant and animal origin and amending Council Directive 91/414/EEC, as amended.
19. CVUA Stuttgart: Keine Clothianidinrückstände in untersuchten Honigen; http://www.untersuchungsämter-bw.de/pub/beitrag.asp?subid= 1&ThemaID=5&ID=796%20&Pdf=No (Feb 9, 2011).
20. EU Pesticides database; http://ec.europa.eu/sanco-pesticides/public/ index.cfm (Feb 9, 2011).
21. Register of Plant Protection Products Authorized in Austria; http://www.psm.ages.at/ (Feb 9, 2011).