Ewe breed differences in fertility after cervical AI with frozen-thawed semen and associated differences in sperm penetration and physicochemical properties of cervical mucus

Animal Reproduction Science

Volumn 129, Issue 1-2, 2011, Pages 37-43

  Richardson, Lorraine ^a,b   Hanrahan, J P ^b   O'Hara, Lydia ^a,b   Donovan, Anne ^b   Fair, Sean ^c   O'Sullivan, Michael ^a   Carrington, Stephen D ^a   Lonergan, Pat ^a   Evans, A C O ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b TEAGASC   (Ireland)

^c UNIVERSITY OF LIMERICK   (Ireland)

Author keywords

AI; Cervix; Mucus; Rheology; Sperm

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; ARTIFICIAL INSEMINATION; CHEMISTRY; FEMALE; FERTILITY; FLUORESCENCE MICROSCOPY; MALE; PH; PHYSIOLOGY; PREGNANCY; SHEEP; STANDARD; UTERINE CERVIX MUCUS; VISCOSITY;

ANIMALS; CERVIX MUCUS; FEMALE; HYDROGEN-ION CONCENTRATION; INSEMINATION, ARTIFICIAL; MALE; MICROSCOPY, FLUORESCENCE; PREGNANCY; SHEEP; SPERM-OVUM INTERACTIONS; VISCOSITY;

EID: 82955249167     PISSN: 03784320     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anireprosci.2011.10.012     Document Type: Article

References (58)

1. Cone R.A. Barrier properties of mucus. Adv. Drug Deliv. Rev. 2009, 61:75-85.
2. Donovan A., Hanrahan J., Duffy P., Boland M. AI in sheep: breed differences in timing of ovulation. Ir. J. Agric. Food Res. 2000, 39:3.
3. Donovan A., Hanrahan J., Duffy P., Byrne G., Boland M. Cervical AI with fresh or frozen-thawed semen: effect of ewe breed. Ir. J. Agric. Food Res. 1999, 38:267.
4. Donovan A., Hanrahan J.P., Kummen E., Duffy P., Boland M.P. Fertility in the ewe following cervical insemination with fresh or frozen-thawed semen at a natural or synchronised oestrus. Anim. Reprod. Sci. 2004, 84:359-368.
5. Donovan, A., Hanrahan, J.P., Lally, T., Boland, M.P., Byrne, G.P., Duffy, P., et al. AI for sheep using frozen-thawed semen. Teagasc, Sheep Research Centre, Athenry, Sheep Series 11; 2001. ISBN 1 84170 152 1.
6. Druart X., Cognie J., Baril G., Clement F., Dacheux J.-L., Gatti J.-L. In vivo imaging of in situ motility of fresh and liquid stored ram spermatozoa in the ewe genital tract. Reproduction 2009, 138:45-53.
7. Eggert-Kruse W., Kohler A., Rohr G.B.R. The pH as an important determinant of sperm-mucus interaction. Fertil. Steril. 1993, 59:617-628.
8. Elstein M. Functions and physical properties of mucus in the female genital tract. Br. Med. Bull. 1978, 34:83-88.
9. Evans G., Maxwell W. Salamon's Artificial Insemination of Sheep and Goats 1987, Butterworths Ply Limited, Sydney.
10. Fair S., Hanrahan J.P., Donovan A., Duffy P., O'Meara C.M., Lonergan P., Evans A.C.O. Hormonal relationships during the periovulatory period among ewe breeds known to differ in fertility after cervical artificial insemination with frozen thawed semen. Anim. Reprod. Sci. 2007, 97:284-294.
11. Fair S., Hanrahan J.P., O'Meara C.M., Duffy P., Rizos D., Wade M., Donovan A., Boland M.P., Lonergan P., Evans A.C.O. Differences between Belclare and Suffolk ewes in fertilization rate, embryo quality and accessory sperm number after cervical or laparoscopic artificial insemination. Theriogenology 2005, 63:1995-2005.
12. Gatti J.-L., Chevrier C., Paquignon M., Dacheux J.-L. External ionic conditions, internal pH and motility of ram and boar spermatozoa. J. Reprod. Fertil. 1993, 98:439-449.
13. Gordon I. Controlled Reproduction in Sheep and Goats 1997, CAB International, Cambridge.
14. Hawk H.W. Sperm survival and transport in the female reproductive tract. J. Dairy Sci. 1983, 66:2645-2660.
15. Hawk H.W., Conley H.H. Involvement of the cervix in sperm transport failures in the reproductive tract of the ewe. Biol. Reprod. 1975, 13:322-328.
16. Heydon R.A., Adams N.R. Comparative morphology and mucus histochemistry of the ruminant cervix: differences between crypt and surface epithelium. Biol. Reprod. 1979, 21:557-562.
17. Honmode J., Pachlag S.V. Time of ovulation and chloride content of vaginal mucus during oestrus in sheep. Indian J. Anim. Sci. 1973, 43:136-140.
18. Innes A.L., Carrington S.D., Thornton D.J., Kirkham S., Rousseau K., Dougherty R.H., Raymond W.W., Caughey G.H., Muller S.J., Fahy J.V. Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma. Am. J. Respir. Crit. Care Med. 2009, 180:203-210.
19. Jordan J., Singer A. The Cervix 1976, The Whitefriars Press Ltd.
20. Kaabi M., Alvarez M., Anel E., Chamorro C.A., Boixo J.C., de Paz P., Anel L. Influence of breed and age on morphometry and depth of inseminating catheter penetration in the ewe cervix: a postmortem study. Theriogenology 2006, 66:1876-1883.
21. Katz D.F., Mills R.N., Pritchett T.R. The movement of human spermatozoa in cervical mucus. J. Reprod. Fertil. 1978, 53:259-265.
22. Katz D.F., Slade D.A., Nakajima S.T. Analysis of pre-ovulatory changes in cervical mucus hydration and sperm penetrability. Adv. Contracept. 1997, 13:143-151.
23. Kopito L.E., Kosasky H.J., Sturgis S.H., Lieberman B.L., Shwachman H. Water and electrolytes in human cervical mucus. Fertil. Steril. 1973, 24:499-506.
24. Kummerfeld H.L., Lorton S.P., Foote R.H. Relationship of spermatozoal migration in cervical mucus to bovine fertility. J. Androl. 1981, 2:103-107.
25. Lai S.K., Wang Y.-Y., Cone R., Wirtz D., Hanes J. Altering mucus rheology to solidify human mucus at the nanoscale. PLoS ONE 2009, 4:e4294.
26. Lai S.K., Wang Y.-Y., Hanes J. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Adv. Drug Deliv. Rev. 2009, 61:158-171.
27. Lai S.K., Wang Y.-Y., Wirtz D., Hanes J. Micro- and macrorheology of mucus. Adv. Drug Deliv. Rev. 2009, 61:86-100.
28. Leethongdee S., Khalid M., Bhatti A., Ponglowhapan S., Kershaw C.M., Scaramuzzi R.J. The effects of the prostaglandin E analogue Misoprostol and follicle-stimulating hormone on cervical penetrability in ewes during the peri-ovulatory period. Theriogenology 2007, 67:767-777.
29. Mattner P.E. Formation and retention of the spermatozoan reservoir in the cervix of the ruminant. Nature 1966, 212:1479-1480.
30. Mattner P.E. The distribution of spermatozoa and leucocytes in the female genital tract in goats and cattle. J. Reprod. Fertil. 1968, 17:253-261.
31. Maxwell W.M.C. Artificial insemination of ewes with frozen-thawed semen at a synchronized oestrus. 1. Effect of time of onset of oestrus, ovulation and insemination on fertility. Anim. Reprod. Sci. 1986, 10:301-308.
32. Menarguez M., Pastor L.M., Odeblad E. Morphological characterization of different human cervical mucus types using light and scanning electron microscopy. Hum. Reprod. 2003, 18:1782-1789.
33. Morales P., Roco M., Vigil P. Human cervical mucus: relationship between biochemical characteristics and ability to allow migration of spermatozoa. Hum. Reprod. 1993, 8:78-83.
34. Mullins J.K., Saacke R.G. Study of the functional anatomy of bovine cervical mucosa with special reference to mucus secretion and sperm transport. Anat. Rec. 1989, 225:106-117.
35. Murase T., Mukohjima K., Sakuguchi S., Ohtani T., Tsubota T., Kita I. Influence of the different batches of estrous cervical mucus mixed for homogenization on penetration by spermatozoa in cattle. J. Reprod. Dev. 2001, 47:109-112.
36. O'Hara L., Hanrahan J.P., Richardson L., Donovan A., Fair S., Evans A.C.O., Lonergan P. Effect of storage duration, storage temperature, and diluent on the viability and fertility of fresh ram sperm. Theriogenology 2010, 73:541-549.
37. Odeblad E. The functional structure of human cervical mucus. Acta Obstet. Gynecol. Scand. 1968, 47:57-79.
38. Olesen I. Effects of cervical insemination with frozen semen on fertility and litter size of Norwegian sheep. Livest. Prod. Sci. 1993, 37:169-184.
39. Paulenz H., Söderquist L., Ådnøy T., Nordstoga A., Gulbrandsen B., Berg K.A. Fertility results after different thawing procedures for ram semen frozen in minitubes and mini straws. Theriogenology 2004, 61:1719-1727.
40. Peek J.C., Matthews C.D. The pH of cervical mucus, quality of semen, and outcome of the post-coital test. Clin. Reprod. Fertil. 1986, 4:217-225.
41. Peris S.I., Bilodeau J.-F., Dufour M., Bailey J.L. Impact of cryopreservation and reactive oxygen species on DNA integrity, lipid peroxidation and functional parameters in ram sperm. Mol. Reprod. Dev. 2007, 74:878-892.
42. Rexroad C.E., Barb C.R. Cervical mucus in estrous ewes after treatment with estrogen, progestogens and intrauterine devices. J. Anim. Sci. 1977, 44:102-105.
43. Rutllant J., López-Béjar M., López-Gatius F. Ultrastructural and rheological properties of bovine vaginal fluid and its relation to sperm motility and fertilization: a review. Reprod. Domest. Anim. 2005, 40:79-86.
44. Rutllant J., López-Gatius F., Camon J., López-Béjar M., López-Plana C. A structural study of the bovine vaginal fluid at estrus. Scanning 1999, 21:204-211.
45. Salamon S., Maxwell W.M.C. Frozen storage of ram semen. I. Processing, freezing, thawing and fertility after cervical insemination. Anim. Reprod. Sci. 1995, 37:185-249.
46. Salamon S., Maxwell W.M.C. Frozen storage of ram semen. II. Causes of low fertility after cervical insemination and methods of improvement. Anim. Reprod. Sci. 1995, 38:1-36.
47. Saltzman W.M., Radomsky M.L., Whaley K.J., Cone R.A. Antibody diffusion in human cervical mucus. Biophys. J. 1994, 66:508-515.
48. Selaive-Villarroel A.B., Kennedy J.P. Fertility studies in young and mature merino ewes. 1. Cervical mucus production. Theriogenology 1983, 20:537-541.
49. Shah P.L., Scott S.F., Knight R.A., Marriott C., Ranasinha C., Hodson M.E. In vivo effects of recombinant human DNase I on sputum in patients with cystic fibrosis. Thorax 1996, 51:119-125.
50. Singh R., Rawal C., Kumar D. Use of oestrus cycle curve of pH values of vaginal mucus to judge a sheep in oestrus. Indian J. Anim. Sci. 1989, 59:1511-1515.
51. Taylor C., Draget K.I., Pearson J.P., Smidsrød O. Mucous systems show a novel mechanical response to applied deformation. Biomacromolecules 2005, 6:1524-1530.
52. Vigil P., Cortes M.E., Zuniga A., Riquelme J., Ceric F. Scanning electron and light microscopy study of the cervical mucus in women with polycystic ovary syndrome. J. Electron Microsc. 2009, 58:21-27.
53. Vigil P., Perez A., Neira J., Morales P. Post-partum cervical mucus: biological and rheological properties. Hum. Reprod. 1991, 6:475-479.
54. Wolf D.P., Blasco L., Khan M.A., Litt M. Human cervical mucus. II. Changes in viscoelasticity during the ovulatory menstrual cycle. Fertil. Steril. 1977, 28:47-52.
55. Wolf D.P., Blasco L., Khan M.A., Litt M. Human cervical mucus. IV. Viscoelasticity and sperm penetrability during the ovulatory menstrual cycle. Fertil. Steril. 1978, 30:163-169.
56. World Health Organisation WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction 1999.
57. Yurewicz E.C., Matsuura F., Moghissi K.S. Structural studies of sialylated oligosaccharides of human midcycle cervical mucin. J. Biol. Chem. 1987, 262:4733-4739.
58. Zibi L. Ewes oestrus prediction with cervico-vaginal mucus acidity and elasticity and with vaginal temperature measurement. Tropicultura 1990, 8:27-30. (in French with English abstract).