Dexamethasone and long-term outcome of tuberculous meningitis in Vietnamese adults and adolescents

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Török, M Estée ^a   Bang, Nguyen Duc ^b   Chau, Tran Thi Hong ^c   Yen, Nguyen Thi Bich ^b   Thwaites, Guy E ^d   Quy, Hoang Thi ^b   Dung, Nguyen Huy ^b   Hien, Tran Tinh ^c   Chinh, Nguyen Tran ^c   Hoang, Hoang Thi Thanh ^e   Wolbers, Marcel ^e,f   Farrar, Jeremy J ^e,f  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Pham Ngoc Thach Hospital   (Viet Nam)

^c UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^d ST THOMAS HOSPITAL   (United Kingdom)

^e OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; ISONIAZID; PLACEBO; PYRAZINAMIDE; RIFAMPICIN; STREPTOMYCIN;

ADJUVANT THERAPY; ADOLESCENT; ADULT; ARTICLE; ASIA; CONTROLLED STUDY; DISABILITY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MORTALITY; MULTICENTER STUDY; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; SURVIVAL RATE; SURVIVAL TIME; TUBERCULOUS MENINGITIS; VIETNAMESE; AGED; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; FEMALE; KAPLAN MEIER METHOD; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODEL; TIME; TREATMENT OUTCOME; VIET NAM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DEXAMETHASONE; FEMALE; FOLLOW-UP STUDIES; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; TIME FACTORS; TREATMENT OUTCOME; TUBERCULOSIS, MENINGEAL; VIETNAM; YOUNG ADULT;

EID: 82955241404     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027821     Document Type: Article

References (16)

1. Thwaites GE, Nguyen DB, Nguyen HD, Hoang TQ, Do TT, et al. (2004) Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N Engl J Med 351: 1741-1751.
2. Shane SJ, Riley C, (1953) Tuberculous meningitis: combined therapy with cortisone and antimicrobial agents. N Engl J Med 249: 829-834.
3. Ashby M, Grant H, (1955) Tuberculous meningitis treated with cortisone. Lancet 268: 65-66.
4. Lepper MH, Spies HW, (1963) The present status of the treatment of tuberculosis of the central nervous system. Ann N Y Acad Sci 106: 106-123.
5. O'Toole RD, Thornton GF, Mukherjee MK, Nath RL, (1969) Dexamethasone in tuberculous meningitis. Relationship of cerebrospinal fluid effects to therapeutic efficacy. Ann Intern Med 70: 39-48.
6. Escobar JA, Belsey MA, Duenas A, Medina P, (1975) Mortality from tuberculous meningitis reduced by steroid therapy. Pediatrics 56: 1050-1055.
7. Girgis NI, Farid Z, Kilpatrick ME, Sultan Y, Mikhail IA, (1991) Dexamethasone adjunctive treatment for tuberculous meningitis. Pediatr Infect Dis J 10: 179-183.
8. Schoeman JF, Van Zyl LE, Laubscher JA, Donald PR, (1997) Effect of corticosteroids on intracranial pressure, computed tomographic findings, and clinical outcome in young children with tuberculous meningitis. Pediatrics 99: 226-231.
9. Prasad K, Volmink J, Menon GR, (2000) Steroids for treating tuberculous meningitis. Cochrane Database Syst Rev.
10. Prasad K, Singh MB, (2008) Corticosteroids for managing tuberculous meningitis. Cochrane Database Syst Rev.
11. Thwaites G, Fisher M, Hemingway C, Scott G, Solomon T, et al. (2009) British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children. J Infect 59: 167-187.
12. National Institute of Health and Clinical Excellence (2011) NICE clinical guideline 117 Tuberculosis: clinical diagnosis and management of tuberculosis, and measures for its prevention and control.
13. (1958) LONG-TERM outcome in tuberculous meningitis. Lancet 2: 837.
14. Schoeman J, Wait J, Burger M, van Zyl F, Fertig G, et al. (2002) Long-term follow up of childhood tuberculous meningitis. Dev Med Child Neurol 44: 522-526.
15. Simmons CP, Thwaites GE, Quyen NT, Chau TT, Mai PP, et al. (2005) The clinical benefit of adjunctive dexamethasone in tuberculous meningitis is not associated with measurable attenuation of peripheral or local immune responses. J Immunol 175: 579-590.
16. R Development Core Team (2009) A language and envirnonment for statistical computing.