Association between polymorphisms of the renin-angiotensin system genes and breast cancer risk: A meta-analysis

Breast Cancer Research and Treatment

Volumn 130, Issue 2, 2011, Pages 561-568

  Xi, Bo ^a   Zeng, Tao ^a   Liu, Liu ^b   Liang, Yajun ^c   Liu, Weina ^a   Hu, Yuehua ^c   Li, Jun ^a  

^a SHANDONG UNIVERSITY   (China)

^b Second Affiliated Hospital of Nan Chang University   (China)

^c GRADUATE SCHOOL OF PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

ACE gene; AGT gene; AGTR1 gene; Breast cancer; Polymorphism; Renin angiotensin system

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANGIOTENSINOGEN; DIPEPTIDYL CARBOXYPEPTIDASE; DNA;

AFRICAN; ARTICLE; ASIAN; BREAST CANCER; CANCER RISK; CAUCASIAN; DNA POLYMORPHISM; ETHNIC GROUP; ETHNICITY; GENETIC MODEL; GENOTYPE; HUMAN; META ANALYSIS; PATHOGENESIS; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ANGIOTENSINOGEN; BREAST NEOPLASMS; CASE-CONTROL STUDIES; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INDEL MUTATION; MODELS, GENETIC; ODDS RATIO; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; RECEPTOR, ANGIOTENSIN, TYPE 1; RENIN-ANGIOTENSIN SYSTEM; RISK FACTORS;

EID: 82955237292     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-011-1602-3     Document Type: Article

References (42)

1. Parkin DM, Bray F, Ferlay J, Pisani P (2005) Global cancer statistics, 2002. CA Cancer J Clin 55(2):74-108 (Pubitemid 40372904)
2. Travis RC, Reeves GK, Green J, Bull D, Tipper SJ, Baker K, Beral V, Peto R, Bell J, Zelenika D, Lathrop M, Million Women Study Collaborators (2010) Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study. Lancet 375(9732):2143-2151
3. Narod SA (2010) Genes, the environment, and breast cancer. Lancet 375(9732):2123-2124
4. Mavaddat N, Antoniou AC, Easton DF, Garcia-Closas M (2010) Genetic susceptibility to breast cancer. Mol Oncol 4(3):174-191
5. Eccles D, Tapper W (2010) The influence of common polymor-phisms on breast cancer. Cancer Treat Res 155:15-32
6. Timmermans PB, Chiu AT, Herblin WF, Wong PC, Smith RD (1992) Angiotensin II receptor subtypes. Am J Hypertens 5(6 Pt 1):406-410
7. Deshayes F, Nahmias C (2005) Angiotensin receptors: a new role in cancer? Trends Endocrinol Metab 16(7):293-299 (Pubitemid 41206635)
8. Villard E, Tiret L, Visvikis S, Rakotovao R, Cambien F, Soubrier F (1996) Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis. Am J Hum Genet 58(6):1268-1278 (Pubitemid 26153839)
9. Sadoshima J, Aoki H, Izumo S (1997) Angiotensin II and serum differentially regulate expression of cyclins, activity of cyclin-dependent kinases, and phosphorylation of retinoblastoma gene product in neonatal cardiac myocytes. Circ Res 80(2):228-241 (Pubitemid 27056986)
10. Lever AF, Hole DJ, Gillis CR, Mc Callum IR, Mc Innes GT, Mac Kinnon PL, Meredith PA, Murray LS, Reid JL, Robertson JW (1998) Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer? Lancet 352(9123):179-184 (Pubitemid 28327802)
11. Célérier J, Cruz A, Lamandé N, Gasc JM, Corvol P (2002) Angiotensinogen and its cleaved derivatives inhibit angiogenesis. Hypertension 39(2):224-228 (Pubitemid 34165219)
12. Gould AB, Green D (1971) Kinetics of the human renin and human substrate reaction. Cardiovasc Res 5(1):86-89
13. Niu W, Qi Y (2010) Association of the angiotensin II type I receptor gene +1166 A>C polymorphism with hypertension risk: evidence from a meta-analysis of 16474 subjects. Hypertens Res 33(11):1137-1143
14. Koh WP, Yuan JM, Van Den Berg D, Lee HP, Yu MC (2005) Polymorphisms in angiotensin II type 1 receptor and angiotensin I-converting enzyme genes and breast cancer risk among Chinese women in Singapore. Carcinogenesis 26(2):459-464 (Pubitemid 40246568)
15. Koh WP, Yuan JM, Sun CL, van den Berg D, Seow A, Lee HP, Yu MC (2003) Angiotensin I-converting enzyme (ACE) gene polymorphism and breast cancer risk among Chinese women in Singapore. Cancer Res 63(3):573-578 (Pubitemid 36158133)
16. Haiman CA, Henderson SO, Bretsky P, Kolonel LN, Henderson BE (2003) Genetic variation in angiotensin I-converting enzyme (ACE) and breast cancer risk: the multiethnic cohort. Cancer Res 63(20):6984-6987 (Pubitemid 37322985)
17. Yuan JM, Koh WP, Sun CL, Lee HP, Yu MC (2005) Green tea intake, ACE gene polymorphism and breast cancer risk among Chinese women in Singapore. Carcinogenesis 26(8):1389-1394 (Pubitemid 41430093)
18. González-Zuloeta Ladd AM, Arias Vásquez A, Sayed-Tabatabaei FA, Coebergh JW, Hofman A, Njajou O, Stricker B, van Duijn C (2005) Angiotensin-converting enzyme gene insertion/deletion polymorphism and breast cancer risk. Cancer Epidemiol Bio-markers Prev 14(9):2143-2146 (Pubitemid 41603259)
19. Yaren A, Turgut S, Kursunluoglu R, Oztop I, Turgut G, Kelten C, Erdem E (2006) Association between the polymorphism of the angiotensin-converting enzyme gene and tumor size of breast cancer in premenopausal patients. Tohoku J Exp Med 210(2):109-116 (Pubitemid 44575585)
20. Yaren A, Turgut S, Kursunluoglu R, Oztop I, Turgut G, Degir-mencioglu S, Kelten C, Erdem E (2007) Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene in patients with breast cancer and effects on prognostic factors. J Investig Med 55(5):255-261 (Pubitemid 47555944)
21. van der Knaap R, Siemes C, Coebergh JW, van Duijn CM, Hofman A, Stricker BH (2008) Renin-angiotensin system inhibitors, angiotensin I-converting enzyme gene insertion/dele-tion polymorphism, and cancer: the Rotterdam Study. Cancer 112(4):748-757 (Pubitemid 351240568)
22. Alves Corrêa SA, Ribeiro de Noronha SM, Nogueira-de-Souza NC, Valleta de Carvalho C, Massad Costa AM, Juvenal Linhares J, Vieira Gomes MT, Guerreiro da Silva ID (2009) Association between the angiotensin-converting enzyme (insertion/deletion) and angiotensin II type 1 receptor (A1166C) polymorphisms and breast cancer among Brazilian women. J Renin Angiotensin Aldosterone Syst 10(1):51-58
23. Mendizábal-Ruiz AP, Morales JA, Castro Marti Nez X, Gutierrez Rubio SA, Valdez L, Vásquez-Camacho JG, Sanchez Corona J, Moran Moguel MC (2010) RAS polymorphisms in cancerous and benign breast tissue. J Renin Angiotensin Aldosterone Syst. doi: 10.1177/1470320310383735
24. Namazi S, Monabati A, Ardeshir-Rouhani-Fard S, Azarpira N (2010) Association of angiotensin I converting enzyme (insertion/deletion) and angiotensin II type 1 receptor (A1166C) polymor-phisms with breast cancer prognostic factors in Iranian popula-tion. Mol Carcinog 49(12):1022-1030
25. González-Zuloeta Ladd AM, Arias Vásquez A, Siemes C, Ya-zdanpanah M, Coebergh JW, Hofman A, Stricker BH, van Duijn CM (2007) Differential roles of Angiotensinogen and Angioten-sin Receptor type 1 polymorphisms in breast cancer risk. Breast Cancer Res Treat 101(3):299-304 (Pubitemid 46169884)
26. Der Simonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7(3):177-188 (Pubitemid 17189972)
27. Mantel N, Haenszel W (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 22(4):719-748
28. Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315(7109): 629-634 (Pubitemid 27387172)
29. Ager EI, Neo J, Christophi C (2008) The renin-angiotensin system and malignancy. Carcinogenesis 29(9):1675-1684
30. Ruiter R, Visser LE, Van Duijn CM, Ch Stricker BH (2011) The ACE insertion/deletion polymorphism and risk of cancer, a review and meta-analysis of the literature. Curr Cancer Drug Targets 11(4):421-430
31. Röcken C, Lendeckel U, Dierkes J, Westphal S, Carl-Mc Grath S, Peters B, Krüger S, Malfertheiner P, Roessner A, Ebert MP (2005) The number of lymph node metastases in gastric cancer correlates with the angiotensin I-converting enzyme gene inser-tion/deletion polymorphism. Clin Cancer Res 11(7):2526-2530 (Pubitemid 40569449)
32. Ebert MP, Lendeckel U, Westphal S, Dierkes J, Glas J, Fol-waczny C, Roessner A, Stolte M, Malfertheiner P, Röcken C (2005) The angiotensin I-converting enzyme gene insertion/deletion polymorphism is linked to early gastric cancer. Cancer Epidemiol Biomarkers Prev 14(12):2987-2989 (Pubitemid 43068835)
33. Goto Y, Ando T, Nishio K, Ishida Y, Kawai S, Goto H, Ha-majima N (2005) The ACE gene polymorphism is associated with the incidence of gastric cancer among H. pylori seropositive subjects with atrophic gastritis. Asian Pac J Cancer Prev 6(4):464-467
34. Sugimoto M, Furuta T, Shirai N, Ikuma M, Sugimura H, Hishida A (2006) Influences of chymase and angiotensin I-converting enzyme gene polymorphisms on gastric cancer risks in Japan. Cancer Epidemiol Biomarkers Prev 15(10):1929-1934 (Pubitemid 44664270)
35. Röcken C, Neumann K, Carl-Mc Grath S, Lage H, Ebert MP, Dierkes J, Jacobi CA, Kalmuk S, Neuhaus P, Neumann U (2007) The gene polymorphism of the angiotensin I-converting enzyme correlates with tumor size and patient survival in colorectal cancer patients. Neoplasia 9(9):716-722 (Pubitemid 47523233)
36. Nikiteas N, Tsigris C, Chatzitheofylaktou A, Yannopoulos A (2007) No association with risk for colorectal cancer of the insertion/deletion polymorphism which affects levels of angio-tensin-converting enzyme. In Vivo 21(6):1065-1068 (Pubitemid 350286337)
37. Toma M, Cimponeriu D, Apostol P, Stavarachi M, Cojocaru M, Belusicǎ L, Crǎciun AM, Radu I, Gavrilǎ L (2009) Lack of association between ACE ID polymorphism and colorectal cancer in Romanian patients. Chirurgia (Bucur) 104(5):553-556
38. Cheon KT, Choi KH, Lee HB, Park SK, Rhee YK, Lee YC (2000) Gene polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme in patients with lung cancer. Lung 178(6):351-360 (Pubitemid 32368237)
39. Nacak M, Nacak I, Sanli M, Ozkur M, Pektaş M, Aynacioǧlu AS (2010) Association of angiotensin converting enzyme gene insertion/deletion polymorphism with lung cancer in Turkey. Cancer Genet Cytogenet 198(1):22-26
40. Medeiros R, Vasconcelos A, Costa S, Pinto D, Lobo F, Morais A, Oliveira J, Lopes C (2004) Linkage of angiotensin I-converting enzyme gene insertion/deletion polymorphism to the progression of human prostate cancer. J Pathol 202(3):330-335 (Pubitemid 38325242)
41. Yigit B, Bozkurt N, Narter F, Yilmaz H, Yucebas E, Isbir T (2007) Effects of ACE I/D polymorphism on prostate cancer risk, tumor grade and metastatis. Anticancer Res 27(2):933-936 (Pubitemid 46587002)
42. Sierra Díaz E, Sánchez Corona J, Rosales Gómez RC, Gutierrez Rubio SA, Vázquez Camacho JG, Solano Moreno H, Morán Moguel MC (2009) Angiotensin-converting enzyme insertion/deletion and angiotensin type 1 receptor A1166C polymorphisms as genetic risk factors in benign prostatic hyperplasia and prostate cancer. J Renin Angiotensin Aldosterone Syst 10(4):241-246