Rapid identification of cyclic tetrapyrrolic photosensitisers for photodynamic therapy using on-line hyphenated LC-PDA-MS coupled with photo-cytotoxicity assay

Phytochemical Analysis

Volumn 23, Issue 1, 2012, Pages 52-59

  Tan, P J ^a   Appleton, D R ^b,c   Mustafa, M R ^b   Lee, H B ^a  

^a CANCER RESEARCH INITIATIVES FOUNDATION   (Malaysia)

^b UNIVERSITY OF MALAYA   (Malaysia)

^c UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

cyclic tetrapyrrole; dereplication; LC PDA MS; photodynamic therapy; photosensitiser

Indexed keywords

CYTOTOXICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLANT EXTRACTS;

CYCLIC TETRAPYRROLE; CYTOTOXIC; CYTOTOXICITY ASSAYS; DEREPLICATION; LIQUID CHROMATOGRAPHY-PHOTODIODE ARRAY-MASS SPECTROMETRY; PHOTODIODE ARRAYS; PHOTOSENSITISER; RAPID IDENTIFICATION; TETRAPYRROLES; TREATMENT MODALITY;

PHOTODYNAMIC THERAPY;

ALPINIA GALANGA EXTRACT; ANAXAGOREA JAVANICA EXTRACT; COSCINIUM FENESTRATUM EXTRACT; GARCINIA ATROVIRIDIS EXTRACT; GARCINIA MANGOSTANA EXTRACT; HIBISCUS CANNABINUS EXTRACT; HIBISCUS SABDARIFFA EXTRACT; IXORA GRANDIFOLIA EXTRACT; LITCHI CHINEN EXTRACT; PHEOPHORBIDE; PHEOPHORBIDE ALPHA METHYL ESTER; PHEOPHORBIDE BETA METHYL ESTER; PHOTOSENSITIZING AGENT; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; TETRAPYRROLE DERIVATIVE; UNCLASSIFIED DRUG; VANILLA FRAGRANS EXTRACT;

ACCURACY; ALPINIA GALANGA; ANAXAGOREA JAVANICA; ARTICLE; BIOASSAY; BIOLOGICAL ACTIVITY; CELL VIABILITY; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; COSCINIUM FENESTRATUM; DIODE; ELECTROSPRAY; FLOW RATE; GARCINIA ATROVIRIDIS; GARCINIA MANGOSTANA; HIBISCUS CANNABINUS; HIBISCUS SABDARIFFA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION PROCEDURE; IXORA GRANDIFOLIA; LIQUID CHROMATOGRAPHY; LITCHI CHINEN; MASS SPECTROMETRY; MEDICINAL PLANT; MOLECULAR WEIGHT; PARTICLE SIZE; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; STRUCTURE ANALYSIS; ULTRAVIOLET SPECTROSCOPY; VANILLA FRAGRANS;

EID: 82955233095     PISSN: 09580344     EISSN: 10991565     Source Type: Journal    
DOI: 10.1002/pca.1324     Document Type: Article

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