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Volumn 301, Issue 6, 2011, Pages 2220-2226

The α-linolenic acid content of flaxseed can prevent the atherogenic effects of dietary trans fat

Author keywords

Atherosclerosis; Linseed; Omega 3 fatty acids; Plaque; Trans fatty acids

Indexed keywords

LINOLENIC ACID; LOW DENSITY LIPOPROTEIN RECEPTOR; TRANS FATTY ACID;

EID: 82955225039     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00958.2010     Document Type: Article
Times cited : (57)

References (48)
  • 1
    • 0028904759 scopus 로고
    • Supplementation with flaxseed oil versus sunflower seed oil in healthy young men consuming a low fat diet: Effects on platelet composition and function
    • Allman MA, Pena MM, Pang D. Supplementation with flaxseed oil versus sunflower seed oil in healthy young men consuming a low fat diet: effects on platelet composition and function. Eur J Clin Nutr 49: 169-178, 1995.
    • (1995) Eur J Clin Nutr , vol.49 , pp. 169-178
    • Allman, M.A.1    Pena, M.M.2    Pang, D.3
  • 3
  • 4
    • 0037812024 scopus 로고    scopus 로고
    • Food labeling: Trans fatty acids in nutrition labeling, nutrient content claims, and health claims. Final rule
    • Anon
    • Anon. Food labeling: trans fatty acids in nutrition labeling, nutrient content claims, and health claims. Final rule. Fed Regist 68: 41433-41506, 2003.
    • (2003) Fed Regist , vol.68 , pp. 41433-41506
  • 8
    • 0030024169 scopus 로고    scopus 로고
    • Mouse models of atherosclerosis
    • Breslow JL. Mouse models of atherosclerosis. Science 272: 685-688, 1996.
    • (1996) Science , vol.272 , pp. 685-688
    • Breslow, J.L.1
  • 9
    • 26044455427 scopus 로고    scopus 로고
    • Low amounts of trans 18:1 fatty acids elevate plasma triacylglycerols but not cholesterol and alter the cellular defence to oxidative stress in mice
    • Cassagno N, Palos-Pinto A, Costet P, Breilh D, Darmon M, Berard AM. Low amounts of trans 18:1 fatty acids elevate plasma triacylglycerols but not cholesterol and alter the cellular defence to oxidative stress in mice. Br J Nutr 94: 346-352, 2005.
    • (2005) Br J Nutr , vol.94 , pp. 346-352
    • Cassagno, N.1    Palos-Pinto, A.2    Costet, P.3    Breilh, D.4    Darmon, M.5    Berard, A.M.6
  • 10
    • 0030038986 scopus 로고    scopus 로고
    • The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil
    • Caughey GE, Mantzioris E, Gibson RA, Cleland LG, James MJ. The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil. Am J Clin Nutr 63: 116-122, 1996.
    • (1996) Am J Clin Nutr , vol.63 , pp. 116-122
    • Caughey, G.E.1    Mantzioris, E.2    Gibson, R.A.3    Cleland, L.G.4    James, M.J.5
  • 11
    • 1842478318 scopus 로고    scopus 로고
    • Trans fatty acids in adipose tissue and the food supply are associated with myocardial infarction
    • Clifton PM, Keogh JB, Noakes M. Trans fatty acids in adipose tissue and the food supply are associated with myocardial infarction. J Nutr 134: 874-879, 2004.
    • (2004) J Nutr , vol.134 , pp. 874-879
    • Clifton, P.M.1    Keogh, J.B.2    Noakes, M.3
  • 12
    • 20444496148 scopus 로고    scopus 로고
    • Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: The National Heart, Lung, and Blood Institute Family Heart Study
    • Djousse L, Arnett DK, Carr JJ, Eckfeldt JH, Hopkins PN, Province MA, Ellison RC. Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart Study. Circulation 111: 2921-2926, 2005.
    • (2005) Circulation , vol.111 , pp. 2921-2926
    • Djousse, L.1    Arnett, D.K.2    Carr, J.J.3    Eckfeldt, J.H.4    Hopkins, P.N.5    Province, M.A.6    Ellison, R.C.7
  • 13
    • 14644396188 scopus 로고    scopus 로고
    • Dietary linolenic acid is associated with a lower prevalence of hypertension in the NHLBI Family Heart Study
    • Djousse L, Arnett DK, Pankow JS, Hopkins PN, Province MA, Ellison RC. Dietary linolenic acid is associated with a lower prevalence of hypertension in the NHLBI Family Heart Study. Hypertension 45: 368-373, 2005.
    • (2005) Hypertension , vol.45 , pp. 368-373
    • Djousse, L.1    Arnett, D.K.2    Pankow, J.S.3    Hopkins, P.N.4    Province, M.A.5    Ellison, R.C.6
  • 17
    • 0037831001 scopus 로고    scopus 로고
    • n-3 Fatty acids and 5-y risks of death and cardiovascular disease events in patients with coronary artery disease
    • Erkkila AT, Lehto S, Pyorala K, Uusitupa MI. n-3 Fatty acids and 5-y risks of death and cardiovascular disease events in patients with coronary artery disease. Am J Clin Nutr 78: 65-71, 2003.
    • (2003) Am J Clin Nutr , vol.78 , pp. 65-71
    • Erkkila, A.T.1    Lehto, S.2    Pyorala, K.3    Uusitupa, M.I.4
  • 20
    • 0033105576 scopus 로고    scopus 로고
    • The atherogenic effects of chlamydia are dependent upon serum cholesterol and specific to the chlamydia pneumoniae species
    • Hu H, Pierce GN, Zhong G. The atherogenic effects of chlamydia are dependent upon serum cholesterol and specific to the chlamydia pneumoniae species. J Clin Invest 103: 747-753, 1999.
    • (1999) J Clin Invest , vol.103 , pp. 747-753
    • Hu, H.1    Pierce, G.N.2    Zhong, G.3
  • 22
    • 34447248546 scopus 로고    scopus 로고
    • A multi-country health-economic evaluation of highly concentrated n-3 polyunsaturated fatty acids in the secondary prevention after myocardial infarction
    • Lamotte M, Annemans L, Kawalec P, Zoellners Y. A multi-country health-economic evaluation of highly concentrated n-3 polyunsaturated fatty acids in the secondary prevention after myocardial infarction. Herz 31, Suppl 3: 74-82, 2006.
    • (2006) Herz , vol.31 , Issue.SUPPL. 3 , pp. 74-82
    • Lamotte, M.1    Annemans, L.2    Kawalec, P.3    Zoellners, Y.4
  • 23
    • 33744802684 scopus 로고    scopus 로고
    • The effect of the regulation on trans fatty acid content in Danish food
    • Leth T, Jensen HG, Mikkelsen AA, Bysted A. The effect of the regulation on trans fatty acid content in Danish food. Atherosclerosis 7, Suppl: 53-56, 2006.
    • (2006) Atherosclerosis , vol.7 , Issue.SUPPL. , pp. 53-56
    • Leth, T.1    Jensen, H.G.2    Mikkelsen, A.A.3    Bysted, A.4
  • 27
    • 62149099518 scopus 로고    scopus 로고
    • Fish oil and the management of hypertriglyceridemia
    • Mattar M, Obeid O. Fish oil and the management of hypertriglyceridemia. Nutr Health 20: 41-49, 2009.
    • (2009) Nutr Health , vol.20 , pp. 41-49
    • Mattar, M.1    Obeid, O.2
  • 28
    • 0035818574 scopus 로고    scopus 로고
    • Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice
    • Merkel M, Velez-Carrasco W, Hudgins LC, Breslow JL. Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice. Proc Natl Acad Sci USA 98: 13294-13299, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13294-13299
    • Merkel, M.1    Velez-Carrasco, W.2    Hudgins, L.C.3    Breslow, J.L.4
  • 31
    • 34948818691 scopus 로고    scopus 로고
    • Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients
    • Paschos GK, Magkos F, Panagiotakos DB, Votteas V, Zampelas A. Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients. Eur J Clin Nutr 61: 1201-1206, 2007.
    • (2007) Eur J Clin Nutr , vol.61 , pp. 1201-1206
    • Paschos, G.K.1    Magkos, F.2    Panagiotakos, D.B.3    Votteas, V.4    Zampelas, A.5
  • 32
  • 33
    • 0030742649 scopus 로고    scopus 로고
    • Dietary flax seed in prevention of hypercholesterolemic atherosclerosis
    • Prasad K. Dietary flax seed in prevention of hypercholesterolemic atherosclerosis. Atherosclerosis 132: 69-76, 1997.
    • (1997) Atherosclerosis , vol.132 , pp. 69-76
    • Prasad, K.1
  • 34
    • 14944371679 scopus 로고    scopus 로고
    • Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseed
    • Prasad K. Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseed. Atherosclerosis 179: 269-275, 2005.
    • (2005) Atherosclerosis , vol.179 , pp. 269-275
    • Prasad, K.1
  • 35
    • 0033574164 scopus 로고    scopus 로고
    • Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed
    • Prasad K. Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. Circulation 99: 1355-1362, 1999.
    • (1999) Circulation , vol.99 , pp. 1355-1362
    • Prasad, K.1
  • 36
    • 0032006237 scopus 로고    scopus 로고
    • Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alphalinolenic acid
    • Prasad K, Mantha SV, Muir AD, Westcott ND. Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alphalinolenic acid. Atherosclerosis 136: 367-375, 1998.
    • (1998) Atherosclerosis , vol.136 , pp. 367-375
    • Prasad, K.1    Mantha, S.V.2    Muir, A.D.3    Westcott, N.D.4
  • 37
    • 0027520675 scopus 로고
    • Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Modulation of macrophage secretory activities
    • Renier G, Skamene E, DeSanctis J, Radzioch D. Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Modulation of macrophage secretory activities. Arterioscler Thromb 13: 1515-1524, 1993.
    • (1993) Arterioscler Thromb , vol.13 , pp. 1515-1524
    • Renier, G.1    Skamene, E.2    Desanctis, J.3    Radzioch, D.4
  • 38
    • 78649315164 scopus 로고    scopus 로고
    • The omega-3 fatty acid alpha linolenic acid within flaxseed provides beneficial cardiovascular effects
    • Rodriguez-Leyva D, Dupasquier CMC, McCullough R, Pierce GN. The omega-3 fatty acid alpha linolenic acid within flaxseed provides beneficial cardiovascular effects. Can J Cardiol 26: 489-496, 2010.
    • (2010) Can J Cardiol , vol.26 , pp. 489-496
    • Rodriguez-Leyva, D.1    Dupasquier, C.M.C.2    McCullough, R.3    Pierce, G.N.4
  • 39
    • 0031794431 scopus 로고    scopus 로고
    • Dietary monounsaturated fatty acids promote aortic atherosclerosis in LDL receptornull, human ApoB100-overexpressing transgenic mice
    • Rudel LL, Kelley K, Sawyer JK, Shah R, Wilson MD. Dietary monounsaturated fatty acids promote aortic atherosclerosis in LDL receptornull, human ApoB100-overexpressing transgenic mice. Arterioscler Thromb Vasc Biol 18: 1818-1827, 1998.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1818-1827
    • Rudel, L.L.1    Kelley, K.2    Sawyer, J.K.3    Shah, R.4    Wilson, M.D.5
  • 40
    • 21244432791 scopus 로고    scopus 로고
    • Antithrombic and anti-atherogenic effects of partially defatted flaxseed meal using a laser-induced thrombosis test in apolipoprotein E and low-density lipoprotein receptor deficient mice
    • Sano T, Oda E, Yamashita T, Shiramasa H, Ijiri Y, Yamamoto J. Antithrombic and anti-atherogenic effects of partially defatted flaxseed meal using a laser-induced thrombosis test in apolipoprotein E and low-density lipoprotein receptor deficient mice. Blood Coagul Fibrinolysis 14: 707-712, 2003.
    • (2003) Blood Coagul Fibrinolysis , vol.14 , pp. 707-712
    • Sano, T.1    Oda, E.2    Yamashita, T.3    Shiramasa, H.4    Ijiri, Y.5    Yamamoto, J.6
  • 42
    • 0041519318 scopus 로고    scopus 로고
    • Exchanging partially hydrogenated fat for palmitic acid in the diet increases LDL-cholesterol and endogenous cholesterol synthesis in normocholesterolemic women
    • Sundram K, French MA, Clandinin MT. Exchanging partially hydrogenated fat for palmitic acid in the diet increases LDL-cholesterol and endogenous cholesterol synthesis in normocholesterolemic women. Eur J Nutr 42: 188-194, 2003.
    • (2003) Eur J Nutr , vol.42 , pp. 188-194
    • Sundram, K.1    French, M.A.2    Clandinin, M.T.3
  • 44
    • 0035661498 scopus 로고    scopus 로고
    • Influence of dietary supplementation with longchain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults
    • Thies F, Miles EA, Nebe-von-Caron G, Powell JR, Hurst TL, Newsholme EA, Calder PC. Influence of dietary supplementation with longchain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. Lipids 36: 1183-1193, 2001.
    • (2001) Lipids , vol.36 , pp. 1183-1193
    • Thies, F.1    Miles, E.A.2    Nebe-von-Caron, G.3    Powell, J.R.4    Hurst, T.L.5    Newsholme, E.A.6    Calder, P.C.7
  • 45
    • 0033528646 scopus 로고    scopus 로고
    • The effect of dietary omega-3 fatty acids on coronary atherosclerosis. A randomized, double-blind, placebo-controlled trial
    • von Schacky C, Angerer P, Kothny W, Theisen K, Mudra H. The effect of dietary omega-3 fatty acids on coronary atherosclerosis. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 130: 554-562, 1999.
    • (1999) Ann Intern Med , vol.130 , pp. 554-562
    • von Schacky, C.1    Angerer, P.2    Kothny, W.3    Theisen, K.4    Mudra, H.5
  • 46
    • 31144455960 scopus 로고    scopus 로고
    • Effect of alpha linolenic acid on cardiovascular risk markers: A systematic review
    • Wendland E, Farmer A, Glasziou P, Neil A. Effect of alpha linolenic acid on cardiovascular risk markers: a systematic review. Heart 92: 166-169, 2006.
    • (2006) Heart , vol.92 , pp. 166-169
    • Wendland, E.1    Farmer, A.2    Glasziou, P.3    Neil, A.4
  • 47
    • 33744823509 scopus 로고    scopus 로고
    • Trans fatty acids and cardiovascular disease-epidemiological data
    • Willett WC. Trans fatty acids and cardiovascular disease-epidemiological data. Atheroscler 7, Suppl: 5-8, 2006.
    • (2006) Atheroscler , vol.7 , Issue.SUPPL. , pp. 5-8
    • Willett, W.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.