Application of thermal analysis and pyrolysis coupled to GC/MS in the qualification of simvastatin pharmaceutical raw material

Journal of Thermal Analysis and Calorimetry

Volumn 106, Issue 3, 2011, Pages 665-670

  Procópio, José Valdilânio Virgulino ^a,b   De Souza, Valmir Gomes ^a   Da Costa, Rodrigo Albuquerque ^b   Correia, Lidiane Pinto ^b   De Souza, Fábio Santos ^a,b   MacÊdo, Rui Oliveira ^a,b  

^a Department of Pharmaceutical Sciences   (Brazil)

^b FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

Pyrolysis; Simvastatin; Thermal analysis; Thermal kinetics

Indexed keywords

DEGRADATION PRODUCTS; GAS CHROMATOGRAPHY/MASS SPECTROMETRY; HYPERCHOLESTEROLEMIA; LOVASTATIN; MELTING PROCESS; PYROLYSIS TEMPERATURE; SIMVASTATIN; STATINS; THERMAL BEHAVIORS; THERMAL CHARACTERIZATION; THERMAL KINETICS;

ACTIVATION ENERGY; BEHAVIORAL RESEARCH; DEGRADATION; THERMOANALYSIS; THERMODYNAMIC STABILITY;

PYROLYSIS;

EID: 82955208230     PISSN: 13886150     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10973-010-1274-y     Document Type: Article

References (11)

1. British Pharmacopoeia. London: United Kingdon, 2009.
2. CD Metcalfe XS Miao 2003 Determination of cholesterol-lowering statin drugs in aqueous samples using liquid chromatography-electrospray ionisation tandem mass spectrometry J Chromatogr A 998 133 141 10.1016/S0021-9673(03)00645- 9
3. SZD Cheng CY Li BH Calhoun L Zhu WW Zhou 2000 Thermal analysis: the next two decades Thermochim Acta 355 59 68 10.1016/S0040-6031(00)00437-8 1:CAS:528:DC%2BD3cXjvF2qu7g%3D
4. EA Moura LP Correia MF Pinto JVV Procópio FS de Souza RO Macêdo 2010 Thermal characterization of the solid state and raw material fluconazole by thermal analysis and pyrolysis coupled to GC/EM J Therm Anal Calorim 100 289 293 10.1007/s10973-009-0473-x 1:CAS:528:DC%2BC3cXkslKmt7o%3D
5. RMF da Silva FPM de Medeiros TG Nascimento RO Macêdo PJR Neto 2009 Thermal characterization of indinavir sulfate using TG, DSC, and DSC-photovisual J Therm Anal Calorim 95 3 1 4
6. O Shulga J Dunn 2004 A simultaneous TG-DTA study of the thermal decomposition of 2-hydroxybenzoic acid, 2-carboxyphenyl ester (salsalate) Thermochim Acta 410 15 21 10.1016/S0040-6031(03)00370-8 1:CAS:528: DC%2BD3sXpvFGhtrg%3D
7. G Chawla P Gupta R Thilagavathi AK Chakraborti AK Bansal 2003 Characterization of solid-state forms of celecoxib Euro J Pharm Sci 20 305 317 10.1016/S0928-0987(03)00201-X 1:CAS:528:DC%2BD3sXosVyltrc%3D
8. AFD Medeiros AFO Santos FS de Souza IDB Júnior J Valdilanio JVV Procópio DP de Santana RO Macêdo 2007 Thermal studies of pre-formulates of metronidazole obtained by spray drying technique J Therm Anal Calorim 89 3 775 781 10.1007/s10973-007-7874-5 1:CAS:528:DC%2BD2sXpvVCisbc%3D
9. AFD Medeiros AFO Santos FS de Souza JVV Procópio MF Pinto RO Macêdo 2007 Thermal stability of paracetamol and its pre-formulates obtained by spray drying J Therm Anal Calorim 88 2 377 382 10.1007/s10973-006- 8006-3 1:CAS:528:DC%2BD2sXlt1Knu7c%3D
10. RO Macêdo TG Nascimento 2002 Quality control of thiabendazole pre-formulation and tablets by TG and DSC coupled to the photovisual system Thermochim Acta 393 85 92 10.1016/S0040-6031(02)00088-6
11. APB Gomes LP Correia MOS Simoes RO Macêdo 2007 Development of thermogravimetric method to quantitative determination of mebendazole J Therm Anal Calorim 87 3 919 925 10.1007/s10973-006-7741-9 1:CAS:528: DC%2BD2sXis1Kntbk%3D