A case of pure red cell aplasia and immune thrombocytopenia complicating systemic lupus erythematosus: Responseto rituximab and cyclophosphamide

Lupus

Volumn 20, Issue 14, 2011, Pages 1547-1550

  Gupta, R K ^a   Ezeonyeji, A N ^a   Thomas, A S ^a   Scully, M A ^a   Ehrenstein, M R ^a   Isenberg, D A ^a  

^a UNIVERSITY COLLEGE HOSPITAL   (United Kingdom)

Author keywords

B cell depletion; immune thrombocytopenic purpura; pure red cell aplasia; systemic lupus erythematosus

Indexed keywords

AZATHIOPRINE; CYCLOPHOSPHAMIDE; IMMUNOGLOBULIN; METHYLPREDNISOLONE; PREDNISOLONE; RITUXIMAB;

ADULT; ARTICLE; AUTOIMMUNE HEPATITIS; CASE REPORT; CORTICOSTEROID THERAPY; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG WITHDRAWAL; FEMALE; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNOSUPPRESSIVE TREATMENT; PRIORITY JOURNAL; PURE RED CELL ANEMIA; RARE DISEASE; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT FAILURE; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANTIBODIES, MONOCLONAL, MURINE-DERIVED; ANTIRHEUMATIC AGENTS; CYCLOPHOSPHAMIDE; FEMALE; GLUCOCORTICOIDS; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; RED-CELL APLASIA, PURE; THROMBOCYTOPENIA; YOUNG ADULT;

EID: 82955207703     PISSN: 09612033     EISSN: 14770962     Source Type: Journal    
DOI: 10.1177/0961203311411349     Document Type: Article

References (12)

1. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1997 ; 409: 1725-1725
2. Walton T, Karim Y, Wright D, Khamashta M, Hughes G. The association of pure red cell aplasia with the antiphospholipid syndrome. Lupus. 2001 ; 1012: 899-901 (Pubitemid 34016874)
3. Elimelakh M, Dayton V, Park KS, et al. Red cell aplasia and autoimmune hemolytic anemia following immunosuppression with alemtuzumab, mycophenolate, and daclizumab in pancreas transplant recipients. Haematologica. 2007 ; 928: 1029-1036 (Pubitemid 350144208)
4. Casadevall N, Dupuy E, Molho-Sabatier P, Tobelem G, Varet B, Mayeux P. Autoantibodies against erythropoietin in a patient with pure red-cell aplasia. N Engl J Med. 1996 ; 33410: 630-633 (Pubitemid 26072120)
5. Sawada K, Fujishima N, Hirokawa M. Acquired pure red cell aplasia: Updated review of treatment. Br J Haematol. 2008 ; 1424: 505-514 (Pubitemid 352020200)
6. Giannouli S, Voulgarelis M, Ziakas PD, Tzioufas AG. Anaemia in systemic lupus erythematosus: From pathophysiology to clinical assessment. Ann Rheum Dis. 2006 ; 652: 144-148 (Pubitemid 43131985)
7. Liu H, Ozaki K, Matsuzaki Y, Abe M, Kosaka M, Saito S. Suppression of haematopoiesis by IgG autoantibodies from patients with systemic lupus erythematosus SLE. Clin Exp Immunol. 1995 ; 1003: 480-485
8. Narra K, Borghaei H, Al-Saleem T, Hoglund M, Smith MR. Pure red cell aplasia in B-cell lymphoproliferative disorder treated with rituximab: Report of two cases and review of the literature. Leuk Res. 2006 ; 301: 109-114 (Pubitemid 41654714)
9. Ghazal H. Successful treatment of pure red cell aplasia with rituximab in patients with chronic lymphocytic leukemia. Blood. 2002 ; 993: 1092-1094 (Pubitemid 34525578)
10. Dungarwalla M, Marsh JC, Tooze JA, et al. Lack of clinical efficacy of rituximab in the treatment of autoimmune neutropenia and pure red cell aplasia: Implications for their pathophysiology. Ann Hematol. 2007 ; 863: 191-197 (Pubitemid 46195991)
11. Cournoyer D, Toffelmire EB, Wells GA, et al. Anti-erythropoietin antibody-mediated pure red cell aplasia after treatment with recombinant erythropoietin products: Recommendations for minimization of risk. J Am Soc Nephrol. 2004 ; 1510: 2728-2734 (Pubitemid 41103380)
12. Schett G, Firbas U, Fureder W, et al. Decreased serum erythropoietin and its relation to anti-erythropoietin antibodies in anaemia of systemic lupus erythematosus. Rheumatology (Oxford). 2001 ; 404: 424-431